Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Alessio Butera"'
Autor:
Alessio Butera, Lena Smirnova, Elisa Ferrando‐May, Thomas Hartung, Thomas Brunner, Marcel Leist, Ivano Amelio
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 9, Pp 1-6 (2023)
Abstract Human health is determined both by genetics (G) and environment (E). This is clearly illustrated in groups of individuals who are exposed to the same environmental factor showing differential responses. A quantitative measure of the gene–e
Externí odkaz:
https://doaj.org/article/7fcae32543ce44f0b3f646c324ba17f9
Publikováno v:
Biology Direct, Vol 17, Iss 1, Pp 1-12 (2022)
Abstract Nuclear organisation and architecture are essential for the maintenance of genomic integrity as well as for the epigenetic regulations and gene expression. Disruption of lamin B1, major structural and functional member of the nuclear lamina,
Externí odkaz:
https://doaj.org/article/e408fbb74e29413196915602e510dfda
Publikováno v:
Discover Oncology, Vol 13, Iss 1, Pp 1-11 (2022)
Abstract Mutations in BAP1 have been identified in a hereditary cancer predisposition syndrome and in sporadic tumours. Individuals carrying familiar BAP1 monoallelic mutations display hypersusceptibility to exposure-associated cancers, such as asbes
Externí odkaz:
https://doaj.org/article/51b5855d8dc6496abc9759373c880700
Autor:
Alessio Butera, Micaela Roy, Carlotta Zampieri, Eleonora Mammarella, Emanuele Panatta, Gerry Melino, Angelo D’Alessandro, Ivano Amelio
Publikováno v:
Biology Direct, Vol 17, Iss 1, Pp 1-11 (2022)
Abstract Adaptation of the lipid metabolism participates in cancer pathogenesis, facilitating energy storage and influencing cell fate and control of molecular signalling. The tumour suppressor protein p53 is a molecular hub of cell metabolism, suppo
Externí odkaz:
https://doaj.org/article/7b593b1a27d3489d9d5f824eebb22219
Autor:
Alessio Butera, Ivano Amelio
Publikováno v:
Cell Cycle. 22:1353-1356
Autor:
Alessio Butera, Massimiliano Agostini, Matteo Cassandri, Francesca De Nicola, Maurizio Fanciulli, Lorenzo D’Ambrosio, Laura Falasca, Roberta Nardacci, Lu Wang, Mauro Piacentini, Richard A. Knight, Wei Jia, Qiang Sun, Yufang Shi, Ying Wang, Eleonora Candi, Gerry Melino
Publikováno v:
Science Advances. 9
An essential function of the epidermis is to provide a physical barrier that prevents the loss of water. Essential mediators of this barrier function include ceramides, cholesterol, and very long chain fatty acids, and their alteration causes human p
Mutations in BAP1 have been identified in a hereditary cancer predisposition syndrome and in sporadic tumours. Individuals carrying familiar BAP1 monoallelic mutations display hypersusceptibility to exposure-associated cancers, such as asbestos-drive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09bcd20828cb428b9cb2b1ca64635bfd
Autor:
Emanuele Panatta, Alessio Butera, Eleonora Mammarella, Consuelo Pitolli, Alessandro Mauriello, Marcel Leist, Richard A. Knight, Gerry Melino, Ivano Amelio
Publikováno v:
Cell Reports
Gene-environment interactions can perturb the epigenome, triggering network alterations that participate in cancer pathogenesis. Integrating epigenomics, transcriptomics, and metabolic analyses with functional perturbation, we show that the tumor sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ecc19bf96f34ccd16eaea134406ebaf
Autor:
Rosanna Pinto, Mariateresa Mancuso, Carmela Marino, Emanuela Pasquali, Claudia Consales, Caterina Merla, Maria Pierdomenico, Vanni Lopresto, Barbara Benassi, Alessio Butera
Publikováno v:
Molecular Neurobiology
We here characterize the response to the extremely low-frequency (ELF) magnetic field (MF, 50 Hz, 1 mT) of SH-SY5Y human neuroblastoma cells, cultured in a three-dimensional (3D) Alvetex® scaffold compared to conventional two-dimensional (2D) monola
Publikováno v:
Journal of molecular biology. 433(15)
Genetics is at the basis of cancer initiation and evolution, but emerging evidence indicates that mutations are not sufficient to produce cancer, indicating a role for epigenetic contributions to the different stages of tumorigenesis. While the genet