Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Alessio, Amatu"'
Autor:
Gianluca Mauri, Giorgio Patelli, Viviana Gori, Calogero Lauricella, Benedetta Mussolin, Alessio Amatu, Katia Bencardino, Federica Tosi, Erica Bonazzina, Emanuela Bonoldi, Alberto Bardelli, Salvatore Siena, Andrea Sartore-Bianchi
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/47b02fe9b6e54c8f96e333df60d08614
Autor:
Gianluca Mauri, Giorgio Patelli, Viviana Gori, Calogero Lauricella, Benedetta Mussolin, Alessio Amatu, Katia Bencardino, Federica Tosi, Erica Bonazzina, Emanuela Bonoldi, Alberto Bardelli, Salvatore Siena, Andrea Sartore-Bianchi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
BackgroundWe aim to identify the prevalence and the role of the MAP2K1 K57N mutation in predicting resistance to anti-EGFR agents in metastatic colorectal cancer (mCRC) patients.MethodsWe retrospectively reviewed tumor-based next generation sequencin
Externí odkaz:
https://doaj.org/article/9d3f7e85a4bd4497ab7bb8887a40c07d
Autor:
Sara Lonardi, Valter Torri, Fortunato Ciardiello, Andrea Sartore-Bianchi, Salvatore Siena, Silvia Marsoni, Alberto Bardelli, Francesca Bergamo, Cosimo Martino, Elisabetta Fenocchio, Federica Tosi, Silvia Ghezzi, Francesco Leone, Vittorina Zagonel, Andrea Ardizzoni, Alessio Amatu, Katia Bencardino, Emanuele Valtorta, Elena Grassi, Emanuela Bonoldi, Anna Sapino, Angelo Vanzulli, Daniele Regge, Giovanni Cappello, Livio Trusolino
Publikováno v:
ESMO Open, Vol 5, Iss 5 (2020)
Background HER2 is a therapeutic target for metastatic colorectal cancer (mCRC), as demonstrated in the pivotal HERACLES-A (HER2 Amplification for Colo-rectaL cancer Enhanced Stratification) trial with trastuzumab and lapatinib. The aim of HERACLES-B
Externí odkaz:
https://doaj.org/article/83670eb46b49449fab6522df0b311a31
Autor:
Alessio Amatu, Gianluca Mauri, Federica Tosi, Katia Bencardino, Erica Bonazzina, Viviana Gori, Lorenzo Ruggieri, Sabrina Arena, Alberto Bardelli, Silvia Marsoni, Salvatore Siena, Andrea Sartore-Bianchi
Publikováno v:
Cancers, Vol 14, Iss 5, p 1197 (2022)
Background: oxaliplatin with fluoropyrimidine is a “mainstay” regarding the upfront treatment of metastatic colorectal cancer (mCRC). In contrast, the efficacy and safety of oxaliplatin-based regimens in late-care settings have been poorly report
Externí odkaz:
https://doaj.org/article/6d3d65bb80c8442ca7ba5c32b9b31c90
Autor:
Andrea Sartore-Bianchi, Filippo Pietrantonio, Sara Lonardi, Benedetta Mussolin, Francesco Rua, Giovanni Crisafulli, Alice Bartolini, Elisabetta Fenocchio, Alessio Amatu, Paolo Manca, Francesca Bergamo, Federica Tosi, Gianluca Mauri, Margherita Ambrosini, Francesca Daniel, Valter Torri, Angelo Vanzulli, Daniele Regge, Giovanni Cappello, Caterina Marchiò, Enrico Berrino, Anna Sapino, Silvia Marsoni, Salvatore Siena, Alberto Bardelli
Publikováno v:
Nature Medicine
Anti-epidermal growth factor receptor (EGFR) monoclonal antibodies are approved for the treatment of RAS wild-type (WT) metastatic colorectal cancer (mCRC), but the emergence of resistance mutations restricts their efficacy. We previously showed that
Autor:
Salvatore Siena, Vasileios Askoxylakis, Glenn Dranoff, Marc R. Pelletier, Lang Ho Lee, Lori A. Iaconis, Sarah M. Choi, Heidi A. Schoenfeld, Kulandayan Subramanian, Ping C. Mahling, Susan E. Cellitti, Alex Cortez, Yasutoshi Kuboki, Jaffer A. Ajani, Alessio Amatu, Toshihiko Doi, Sae-Won Han, Filip Janku
Immune-stimulator antibody conjugates (ISAC) combining tumor-targeting monoclonal antibodies with immunostimulatory agents allow targeted delivery of immune activators into tumors. NJH395 is a novel, first-in-class ISAC comprising a Toll‐like recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7971b7d07116fc0c53b6de7673a36ee9
https://doi.org/10.1158/2326-6066.c.6551021.v1
https://doi.org/10.1158/2326-6066.c.6551021.v1
Autor:
Salvatore Siena, Vasileios Askoxylakis, Glenn Dranoff, Marc R. Pelletier, Lang Ho Lee, Lori A. Iaconis, Sarah M. Choi, Heidi A. Schoenfeld, Kulandayan Subramanian, Ping C. Mahling, Susan E. Cellitti, Alex Cortez, Yasutoshi Kuboki, Jaffer A. Ajani, Alessio Amatu, Toshihiko Doi, Sae-Won Han, Filip Janku
Supplementary Figure from Preclinical Characterization and Phase I Study of an Anti–HER2-TLR7 Immune-Stimulator Antibody Conjugate in Patients with HER2+ Malignancies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704176b41c46a7157ecea1d47d7de480
https://doi.org/10.1158/2326-6066.22545746.v1
https://doi.org/10.1158/2326-6066.22545746.v1
Autor:
Alberto Bardelli, Salvatore Siena, Silvia Marsoni, Federica Di Nicolantonio, Giovanni Germano, Emanuela Bonoldi, Emanuele Valtorta, Federica Morano, Laura Idotta, Federica Tosi, Pietro Paolo Vitiello, Valeria Pessei, Maria Giulia Zampino, Nicola Personeni, Paolo Battuello, Gianluca Mauri, Paolo Luraghi, Alice Bartolini, Andrea Cassingena, Ludovic Barault, Marco Macagno, Alessio Amatu, Filippo Pietrantonio, Luca Lazzari, Andrea Sartore-Bianchi, Giovanni Crisafulli
Supplementary Figure from Temozolomide Treatment Alters Mismatch Repair and Boosts Mutational Burden in Tumor and Blood of Colorectal Cancer Patients
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12c88c3aa4671914cfc6cc7801152c57
https://doi.org/10.1158/2159-8290.22541308
https://doi.org/10.1158/2159-8290.22541308
Autor:
Salvatore Siena, Vasileios Askoxylakis, Glenn Dranoff, Marc R. Pelletier, Lang Ho Lee, Lori A. Iaconis, Sarah M. Choi, Heidi A. Schoenfeld, Kulandayan Subramanian, Ping C. Mahling, Susan E. Cellitti, Alex Cortez, Yasutoshi Kuboki, Jaffer A. Ajani, Alessio Amatu, Toshihiko Doi, Sae-Won Han, Filip Janku
Supplementary Data from Preclinical Characterization and Phase I Study of an Anti–HER2-TLR7 Immune-Stimulator Antibody Conjugate in Patients with HER2+ Malignancies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5f94745c1462cb05163a0a0fdf5af8
https://doi.org/10.1158/2326-6066.22545749.v1
https://doi.org/10.1158/2326-6066.22545749.v1
Autor:
Filippo G. De Braud, Alice T. Shaw, Pratik S. Multani, Zachary Hornby, Edna Chow-Maneval, David Luo, Rupal Patel, Ann D. Johnson, Karey Kowalski, Jason Christiansen, Gang Li, Elena Ardini, Matteo Duca, Silvia Damian, Sara Cresta, Angelo Vanzulli, Andrea Sartore-Bianchi, Laura Palmeri, Katia Bencardino, Alessio Amatu, Michele Schirru, Giovanna Marrapese, Giulio Cerea, Laura Giannetta, Robert Doebele, Stephen V. Liu, Jennifer J. Wheler, Anna F. Farago, Todd M. Bauer, Jeeyun Lee, Myung Ju Ahn, Manish Patel, Sai-Hong Ignatius Ou, Salvatore Siena, Alexander Drilon
DOC- 25K, Supplementary Tables 1-6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd48e1f6275a397aaf95adba086a40ff
https://doi.org/10.1158/2159-8290.22531320.v1
https://doi.org/10.1158/2159-8290.22531320.v1