Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Alessia Stornetta"'
Autor:
Amanda Mandarino Alves, Chiara Lecchi, Sharon Lopez, Alessia Stornetta, Prince P. Mathai, Peter W. Villalta, Satoshi Ishii, Emily P. Balskus, Silvia Balbo, Alexander Khoruts
Publikováno v:
Gut Microbes, Vol 16, Iss 1 (2024)
Colibactin is a recently characterized pro-carcinogenic genotoxin produced by pks+ Escherichia coli. We hypothesized that cystic fibrosis (CF)-associated dysfunctional mucus structure increases the vulnerability of host mucosa to colibactin-induced D
Externí odkaz:
https://doaj.org/article/00a6fb06754e45578e5450129bcd8f37
Autor:
Kristine Walters, Alessia Stornetta, Foster Jacobs, Peter W. Villalta, Maria Razzoli, Marianne Grant, Beshay Zordoky, Alessandro Bartolomucci, Antonella Borgatti, Silvia Balbo
Publikováno v:
BMC Veterinary Research, Vol 17, Iss 1, Pp 1-16 (2021)
Abstract Background Both human and veterinary cancer chemotherapy are undergoing a paradigm shift from a “one size fits all” approach to more personalized, patient-oriented treatment strategies. Personalized chemotherapy is dependent on the ident
Externí odkaz:
https://doaj.org/article/245ee7d40f0946bb8f4189111ee4f492
Publikováno v:
Frontiers in Medical Technology, Vol 4 (2022)
Per ISO 10993-1:2018, a processing change to a medical device requires re-evaluation of biological risk. Here, we present the biological evaluation of a marketed cardiovascular implant following a detergent formulation change. This change was initial
Externí odkaz:
https://doaj.org/article/9f8a7f953a9f4029aebbc01b876a3f23
Publikováno v:
Cancers, Vol 10, Iss 3, p 74 (2018)
The authors would like to make a correction to their published paper[...]
Externí odkaz:
https://doaj.org/article/506992e1b0984c09b82e4ef02e05338b
Publikováno v:
Cancers, Vol 10, Iss 1, p 20 (2018)
Alcohol is classified by the International Agency for Research on Cancer (IARC) as a human carcinogen and its consumption has been associated to an increased risk of liver, breast, colorectum, and upper aerodigestive tract (UADT) cancers. Its mechani
Externí odkaz:
https://doaj.org/article/844bde66534f406e9f766245d205bf30
Autor:
Matthew R. Volpe, José A. Velilla, Martin Daniel-Ivad, Jenny J. Yao, Alessia Stornetta, Peter W. Villalta, Hsin-Che Huang, Daniel A. Bachovchin, Silvia Balbo, Rachelle Gaudet, Emily P. Balskus
Publikováno v:
Nature Chemical Biology. 19:159-167
The human gut bacterial genotoxin colibactin is a possible key driver of colorectal cancer (CRC) development. Understanding colibactin’s biological effects remains difficult owing to the instability of the proposed active species and the complexity
Autor:
Morwena J. Solivio, Alessia Stornetta, Julie Gilissen, Peter W. Villalta, Sofie Deschoemaeker, Arne Heyerick, Ludwig Dubois, Silvia Balbo
Publikováno v:
Chemical Research in Toxicology, 35(2), 275-282. American Chemical Society
Many chemotherapeutic drugs exert their cytotoxicity through the formation of DNA modifications (adducts), which interfere with DNA replication, an overactive process in rapidly dividing cancer cells. Side effects from the therapy are common, however
Autor:
Alessia Stornetta, Peter W. Villalta, Kevin Murray, Emily P. Balskus, Erik S. Carlson, Silvia Balbo
Publikováno v:
Anal Chem
Development of high resolution/accurate mass liquid chromatography-coupled tandem mass spectrometry (LC-MS/MS) methodology enables the characterization of covalently modified DNA induced by interaction with genotoxic agents in complex biological samp
Autor:
William E. Smith, Yen Yi Ho, Pramod Upadhyaya, Silvia Balbo, Donna Seabloom, Marissa K. Oram, Alessia Stornetta, Karin R. Vevang, Lisa A. Peterson, Stephen S. Hecht, M. Gerard O'Sullivan, Timothy S. Wiedmann, Andrew C. Floeder, Lin Zhang, Monica Flavin
Publikováno v:
Chemical Research in Toxicology. 34:723-732
Tobacco smoke is a complex mixture of chemicals, many of which are toxic and carcinogenic. Hazard assessments of tobacco smoke exposure have predominantly focused on either single chemical exposures or the more complex mixtures of tobacco smoke or it
Autor:
Matthew R, Volpe, José A, Velilla, Martin, Daniel-Ivad, Jenny J, Yao, Alessia, Stornetta, Peter W, Villalta, Hsin-Che, Huang, Daniel A, Bachovchin, Silvia, Balbo, Rachelle, Gaudet, Emily P, Balskus
Publikováno v:
Nature chemical biology.
The human gut bacterial genotoxin colibactin is a possible key driver of colorectal cancer (CRC) development. Understanding colibactin's biological effects remains difficult owing to the instability of the proposed active species and the complexity o