Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Alessia Sardo"'
Publikováno v:
Protein expression and purification
The avidin-biotin technology has many applications, including molecular detection; immobilization; protein purification; construction of supramolecular assemblies and artificial metalloenzymes. Here we present the recombinant expression of novel biot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::826f4473e1670c5a264177e7a1ed756c
https://doi.org/10.1016/j.pep.2011.01.003
https://doi.org/10.1016/j.pep.2011.01.003
Autor:
Therese Wohlschlager, Alessia Sardo, Tilman Schirmer, Tillmann Heinisch, Claudia Massa, Jeremy M. Zimbron, Julieta Gradinaru, Thomas R. Ward, Marc Creus
Publikováno v:
Chemistry
The mode of action of precious metal anticancer metallodrugs is generally believed to involve DNA as a target. However, the poor specificity of such drugs often requires high doses and leads to undesirable side-effects. With the aim of improving the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::159a399dbd104d45aed07b3a78b674e8
https://doi.org/10.1002/chem.201001573
https://doi.org/10.1002/chem.201001573
Publikováno v:
Current opinion in biotechnology
Artificial metalloenzymes result from the introduction of a catalytically competent non-native metal cofactor within a protein environment. In the present contribution, we summarize the recent achievements in the design and the optimization of such p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e700d1355faab77b8da462c7430f27a2
Autor:
Anca Pordea, Christophe Letondor, Isolde LeTrong, Thomas R. Ward, Marc Creus, Thibaud Rossel, Alessia Sardo, Anita Ivanova, Ronald E. Stenkamp
Publikováno v:
Angewandte Chemie International Edition. 47:1400-1404
A structure is worth a thousand words: guided by the crystal structure of an S-selective artificial transfer hydrogenase, designed evolution was used to optimize the selectivity of hybrid catalysts. Fine-tuning of the second coordination sphere of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13934e2a195997a556685ab6aae8f09b
https://doi.org/10.1002/anie.200704865
https://doi.org/10.1002/anie.200704865
Autor:
Anita Ivanova, Thomas R. Ward, Marc Creus, Julien Pierron, Julieta Gradinaru, Ines Hafner, Christophe Malan, Alessia Sardo
Publikováno v:
Angewandte Chemie International Edition. 47:701-705
Palladium in the active site: The incorporation of a biotinylated palladium diphosphine within streptavidin yielded an artificial metalloenzyme for the title reaction (see scheme). Chemogenetic optimization of the catalyst by the introduction of a sp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7457ca68d85fa77cadca763e5ec744ed
https://doi.org/10.1002/anie.200703159
https://doi.org/10.1002/anie.200703159
OsO4·streptavidin: a tunable hybrid catalyst for the enantioselective cis-dihydroxylation of olefins
Autor:
Tillmann Heinisch, Jean-Christophe Prost, Yvonne M. Wilson, Anca Pordea, Valentin Köhler, Tilman Schirmer, Thomas R. Ward, Marc Creus, Livia Knörr, Jincheng Mao, Alessia Sardo
Publikováno v:
Angewandte Chemie
Enzymatic and homogeneous catalysis have evolved independently to address the challenges in the synthesis of enantiopure products. With the aim of complementing these fields, artificial metalloenzymes, which combine the structural diversity of biocat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9610e6355d4a54ac5dcadca24df4278f
https://pubmed.ncbi.nlm.nih.gov/21948623
https://pubmed.ncbi.nlm.nih.gov/21948623
Autor:
Isolde LeTrong, Alessia Sardo, Anita Ivanova, Christophe Letondor, Anca Pordea, Thomas R. Ward, Marc Creus, Thibaud Rossel, Ronald E. Stenkamp
Publikováno v:
Angewandte Chemie International Edition. 47:1342-1342
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2cf0633351dc6b59a93e96f1b421acc
https://doi.org/10.1002/anie.200890025
https://doi.org/10.1002/anie.200890025
Autor:
Isolde LeTrong, Anca Pordea, Anita Ivanova, Alessia Sardo, Christophe Letondor, Thomas R. Ward, Marc Creus, Ronald E. Stenkamp, Thibaud Rossel
Publikováno v:
Angewandte Chemie. 120:1362-1362
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::67eda2711a90609a0ce1e4173868f36e
https://doi.org/10.1002/ange.200890025
https://doi.org/10.1002/ange.200890025