Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Alessia Roma"'
Autor:
Varsha Jayasankar, Nikolina Vrdoljak, Alessia Roma, Nawaz Ahmed, Matthew Tcheng, Mark D. Minden, Paul A. Spagnuolo
Publikováno v:
ACS Omega, Vol 7, Iss 2, Pp 1682-1693 (2022)
Externí odkaz:
https://doaj.org/article/d27f98b1386b4451bd5031a57dcd5a79
Autor:
Alessia Roma, Matthew Tcheng, Nawaz Ahmed, Sarah Walker, Preethi Jayanth, Mark D. Minden, Julie A. Reisz, Angelo D'Alessandro, Jakub Rohlena, Paul A. Spagnuolo
Publikováno v:
Phytomedicine Plus, Vol 2, Iss 3, Pp 100300- (2022)
Background: Acute myeloid leukemia (AML) is a hematopoietic malignancy that results from the accumulation of undifferentiated myeloid cells in the peripheral blood and bone marrow. Limited therapeutics contribute to unfavorable patient outcomes, high
Externí odkaz:
https://doaj.org/article/d6cba8b6f3d64bb79a2161045226f5c7
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 18, Iss 4 (2015)
Purpose: Natural products have been a great source of medications used in conventional medicines for the treatment of various diseases; more importantly, they have played a significant role in the development of anti-cancer drugs for a number of deca
Externí odkaz:
https://doaj.org/article/fe8d4e3ca2d2453691df458610238071
Autor:
Pamela Ovadje, Dennis Ma, Phillip Tremblay, Alessia Roma, Matthew Steckle, Jose-Antonio Guerrero, John Thor Arnason, Siyaram Pandey
Publikováno v:
PLoS ONE, Vol 9, Iss 11, p e113250 (2014)
BACKGROUND:Currently chemotherapy is limited mostly to genotoxic drugs that are associated with severe side effects due to non-selective targeting of normal tissue. Natural products play a significant role in the development of most chemotherapeutic
Externí odkaz:
https://doaj.org/article/7418ae0815cc495ba6031852955f777a
Autor:
Paul A. Spagnuolo, Angelo D'Alessandro, Rachel Culp-Hill, Julie A. Reisz, Andrew C. Doxey, Jessica Luc, Praveen P. Nekkar Rao, Kristin Hope, Mark D. Minden, Preethi Jayanth, Sarah Walker, Nawaz Ahmed, Matthew Tcheng, Alessia Roma
Supplementary Figure from Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ab0cf07dbc910ec9d05a0fcb07970e6
https://doi.org/10.1158/1541-7786.22528076.v1
https://doi.org/10.1158/1541-7786.22528076.v1
Autor:
Paul A. Spagnuolo, Angelo D'Alessandro, Rachel Culp-Hill, Julie A. Reisz, Andrew C. Doxey, Jessica Luc, Praveen P. Nekkar Rao, Kristin Hope, Mark D. Minden, Preethi Jayanth, Sarah Walker, Nawaz Ahmed, Matthew Tcheng, Alessia Roma
Supplementary Data from Glutamine Metabolism Mediates Sensitivity to Respiratory Complex II Inhibition in Acute Myeloid Leukemia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86ecf07276bacf58f9440d1b432cabf6
https://doi.org/10.1158/1541-7786.22528079.v1
https://doi.org/10.1158/1541-7786.22528079.v1
Autor:
Paul A. Spagnuolo, Angelo D'Alessandro, Rachel Culp-Hill, Julie A. Reisz, Andrew C. Doxey, Jessica Luc, Praveen P. Nekkar Rao, Kristin Hope, Mark D. Minden, Preethi Jayanth, Sarah Walker, Nawaz Ahmed, Matthew Tcheng, Alessia Roma
Acute myeloid leukemia (AML) is a hematologic malignancy metabolically dependent on oxidative phosphorylation and mitochondrial electron transport chain (ETC) activity. AML cells are distinct from their normal hematopoietic counterparts by this metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e265a1dc866eec9722f84e745fe748f
https://doi.org/10.1158/1541-7786.c.6545609
https://doi.org/10.1158/1541-7786.c.6545609
Autor:
Jerry Vockley, Kristin J Hope, Kevin A Rea, Tariq A. Akhtar, Aaron D. Schimmer, Al-Walid Mohsen, Nawaz Ahmed, Paul A. Spagnuolo, Angelo D'Alessandro, Richard W. Smith, Matthew Tcheng, David A. Hess, Eric Bohrnsen, Mark D. Minden, Preethi Jayanth, Alessia Roma
Publikováno v:
Blood
Paediatrics Publications
Paediatrics Publications
Acute myeloid leukemia (AML) cells have an atypical metabolic phenotype characterized by increased mitochondrial mass, as well as a greater reliance on oxidative phosphorylation and fatty acid oxidation (FAO) for survival. To exploit this altered met
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::443da9fa36eecb0015e1eae59dab6e2e
https://doi.org/10.1182/blood.2020008551
https://doi.org/10.1182/blood.2020008551
Autor:
Michael A. Rogers, Behnoush Kermanshahi, Saeed M. Ghazani, Katrina Tait, Matthew Tcheng, Richard W. Smith, Shannon P. Callender, Paul A. Spagnuolo, Shawn D. Wettig, William Tam, Nawaz Ahmed, Alessia Roma, Alejandro G. Marangoni
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-14 (2020)
Scientific Reports
Scientific Reports
Avocado (Persea americana Mill.; Lauraceae) seed-derived polyhydroxylated fatty alcohols (PFAs) or polyols (i.e., avocadene and avocadyne) are metabolic modulators that selectively induce apoptosis of leukemia stem cells and reverse pathologies assoc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e9f10fe2260d90fd530300996d8a004
http://link.springer.com/article/10.1038/s41598-020-62334-y
http://link.springer.com/article/10.1038/s41598-020-62334-y
Autor:
Alessia Roma, Matthew Tcheng, Nawaz Ahmed, Sarah Walker, Preethi Jayanth, Mark D. Minden, Kristin Hope, Praveen P. Nekkar Rao, Jessica Luc, Andrew C. Doxey, Julie A. Reisz, Rachel Culp-Hill, Angelo D'Alessandro, Paul A. Spagnuolo
Publikováno v:
Molecular cancer research : MCR. 20(11)
Acute myeloid leukemia (AML) is a hematologic malignancy metabolically dependent on oxidative phosphorylation and mitochondrial electron transport chain (ETC) activity. AML cells are distinct from their normal hematopoietic counterparts by this metab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a944870ad0ff7be0a93ac0b907966bb4
https://pubmed.ncbi.nlm.nih.gov/35994381
https://pubmed.ncbi.nlm.nih.gov/35994381