Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alessia Maddalena"'
Autor:
Alessia Maddalena, Andri Signorell, Andreas Raschig, Isabella Heuser, Christoph Hock, Harald Hampel, Gerhard W. Eschweiler, Roger M. Nitsch, Klaus Hager, Wolfgang H. Oertel, Franz Müller-Spahn, Charo Gonzalez-Agosti, Marion Wienrich, Thomas Müller-Thomsen
Publikováno v:
Amyloid. 10:1-6
The amyloid beta-peptides A beta 40 and A beta 42 are highly amyloidogenic constituents of brain beta-amyloid plaques in Alzheimer's disease (AD). Lowering their formation may be achieved by modulating the activities of proteases that cleave the amyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::744c5f98c05f504b6044075e4b10f301
https://doi.org/10.3109/13506120308995249
https://doi.org/10.3109/13506120308995249
Autor:
Johannes Streffer, M. Axel Wollmer, Luigi M.E. Grimaldi, Ulrike Lemke, Roger M. Nitsch, Daniel Umbricht, Andreas Papassotiropoulos, Alessia Maddalena, Giuliana Salani, Simone Bosshardt, Hans H. Jung, George P. Paraskevas, Katharina Henke, Christoph Hock, Claudia Bieber, Elisabeth Kapaki, Thomas Hegi, Dominique J.-F. de Quervain, Nadia Degonda, Thomas Pasch
Publikováno v:
Psychiatric Genetics. 12:155-160
Tissue inhibitor of metalloproteinases 1 (TIMP-1) inhibits several proteinases including a disintegrin and metalloproteinase 10 (ADAM10), a major alpha-secretase that cleaves the beta-amyloid precursor protein within its amyloidogenic Abeta domain. T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9e33f21ec7e13ca63671356acdede22e
https://doi.org/10.1097/00041444-200209000-00006
https://doi.org/10.1097/00041444-200209000-00006
Autor:
Alessia Maddalena, Till Voigtländer, Johannes A. Hainfellner, Adriano Aguzzi, Peter R. Mazal, Thomas Ströbel, Herbert Budka
Publikováno v:
Journal of Neuropathology & Experimental Neurology. 60:449-461
Neuropathologists use anti-glial fibrillary acidic protein (GFAP) antibodies as specific markers for glial cells, and neurobiologists use GFAP for targeting transgenes to glial cells. Since GFAP has also been detected in non-glial cells, we systemati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1b17b4bfd4c94ab077d23dac7b2afeef
https://doi.org/10.1093/jnen/60.5.449
https://doi.org/10.1093/jnen/60.5.449
Publikováno v:
Brain Pathol
Human low‐grade astrocytomas frequently recur and progress to states of higher malignancy. During tumor progression TP53 alterations are among the first genetic changes, while derangement of the p16/p14ARF/RB‐1 system occurs later. To probe the p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9fe9d4c51673090e3b95dc7e5f89924
https://doi.org/10.1111/j.1750-3639.1999.tb00544.x
https://doi.org/10.1111/j.1750-3639.1999.tb00544.x
Autor:
Johannes A. Hainfellner, Jean-Philippe Theurillat, Alessia Maddalena, Adriano Aguzzi, Jakob Weissenberger
Publikováno v:
Scopus-Elsevier
Angiogenesis is a prerequisite for solid tumor growth. Glioblastoma multiforme, the most common malignant brain tumor, is characterized by extensive vascular proliferation. We previously showed that transgenic mice expressing a GFAP-v-src fusion gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26af661f32240a5ae8a900b7ac0bec1a
https://doi.org/10.1016/s0002-9440(10)65303-5
https://doi.org/10.1016/s0002-9440(10)65303-5
Autor:
Luigi M.E. Grimaldi, M. Axel Wollmer, Thomas Hegi, Sibylle Wolleb, Elisabeth Kapaki, Philippe Amouyel, Andreas Papassotiropoulos, Johannes Streffer, Alessia Maddalena, Uwe Konietzko, John Hardy, Jean-Charles Lambert, Heinz Von Der Kammer, Hans H. Jung, Kim-Dung Huynh, Christoph Hock, Heiko Braak, Thomas Pasch, Dieter Lütjohann, Roger M. Nitsch, Magdalini Tsolaki, Dietmar Rudolf Thal, Rivka Ravid, Brigitte Schneider, Fabienne Wavrant-De Vrièze, Evgeny I. Rogaev
Alzheimer’s disease (AD) is the most common cause of dementia. It is characterized by β-amyloid (Aβ) plaques, neurofibrillary tangles and the degeneration of specifically vulnerable brain neurons. We observed high expression of the cholesterol 25
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c44903f6c8c895c063bdc08fc2301d1
https://www.zora.uzh.ch/id/eprint/49534/
https://www.zora.uzh.ch/id/eprint/49534/
We report the association of long-term clozapine and clomipramine therapy with severe esophageal dilation and hypomotility in a patient with chronic schizophrenia leading to life threatening aspiration pneumonia. Severe aspiration pneumonia manifeste
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52f092a0823d37f9f380c578216cadbd
https://www.zora.uzh.ch/id/eprint/49356/
https://www.zora.uzh.ch/id/eprint/49356/
Autor:
Alessia Maddalena, Christoph Hock, Danielle Gretener, Andreas Papassotiropoulos, Roger M. Nitsch
Publikováno v:
The Living Brain and Alzheimer’s Disease ISBN: 9783642639272
The antemortem diagnosis of probable Alzheimer’s disease (AD) requires time-consuming and costly procedures. Therefore, biomarkers that can direct the physician rapidly to the correct diagnosis are highly desirable. According to the consensus repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::76d3721759b2ff3caaf5601c412825d4
https://doi.org/10.1007/978-3-642-59300-0_2
https://doi.org/10.1007/978-3-642-59300-0_2
Autor:
Britta Müller-Tillmanns, Thomas Hegi, Alessia Maddalena, Christoph Hock, Roger M. Nitsch, Hans H. Jung, Andreas Papassotiropoulos
Publikováno v:
Archives of Neurology. 60
BACKGROUND: The antemortem diagnosis of Alzheimer disease (AD) requires time-consuming and costly procedures. Therefore, biochemical tests that can direct the physician rapidly to the correct diagnosis are highly desirable. Measurement of single bioc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ee2b41e0b46e1c8451ff2293acebd7
https://doi.org/10.1001/archneur.60.9.1202
https://doi.org/10.1001/archneur.60.9.1202
Autor:
Uwe Konietzko, Johannes Streffer, Alessia Maddalena, M. Axel Wollmer, Jay Tracy, Britta Müller-Tillmanns, Eva Moritz, Roger M. Nitsch, Daniel Umbricht, Andri Signorell, Esmeralda Garcia, Dominique J.-F. de Quervain, Katharina Henke, Andreas Papassotiropoulos, Marc Hofmann, Christoph Hock, Ulrike Lemke
Publikováno v:
Neuron. 38(4)
To test whether antibodies against beta-amyloid are effective in slowing progression of Alzheimer's disease, we assessed cognitive functions in 30 patients who received a prime and a booster immunization of aggregated Abeta(42) over a 1 year period i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ce624cef23f35f599ff01abdfffd026
https://pubmed.ncbi.nlm.nih.gov/12765602
https://pubmed.ncbi.nlm.nih.gov/12765602