Bioorthogonal Swarming: In Situ Generation of Dendrimers

Autor: Shuo Zhang, Assel Baibek, Mark Bradley, Annamaria Lilienkampf, Muhammed Ucuncu, Jin Geng, Alessia Gambardella, Yichuan Zhang, Jessica Clavadetscher, Inga Litzen

Publikováno v: Zhang, Y, Üçüncü, M, Gambardella, A, Baibek, A, Geng, J, Zhang, S, Clavadetscher, J, Litzen, I, Bradley, M & Lilienkampf, A 2020, ' Bioorthogonal Swarming: In Situ Generation of Dendrimers ', Journal of the American Chemical Society, vol. 142, no. 52, pp. 21615–21621 . https://doi.org/10.1021/jacs.0c07869

With the aid of bioorthogonal chemistry, we demonstrate the fabrication of synthetic dendrimers in situ around living cells. Using tetrazine dienophile and aminooxyl/hydrazide aldehyde chemistries, the density of functional groups on the dendrimers e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ec74f3828c996c1e46a0d64a776a192
https://pubmed.ncbi.nlm.nih.gov/33326212

A Dual Killing Strategy: Photocatalytic Generation of Singlet Oxygen with Concomitant Pt

Autor: Daniel J, Norman, Alessia, Gambardella, Andrew R, Mount, Alan F, Murray, Mark, Bradley

Publikováno v: Angewandte Chemie (International ed. in English). 58(40)

A ruthenium-based mitochondrial-targeting photosensitiser that undergoes efficient cell uptake, enables the rapid catalytic conversion of Pt

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::683ff4f6dd661af7ca7785f588a03e08
https://pubmed.ncbi.nlm.nih.gov/31397963

Tetrazine‐responsive self‐immolative linkers

Autor: Elsa Valero, Annamaria Lilienkampf, Alessia Gambardella, Mark Bradley, Sarthak Jain, Kevin Neumann, Sarah E. Walker

Publikováno v: Neumann, K, Jain, S, Gambardella, A, Walker, S E, Valero, E, Lilienkampf, A & Bradley, M 2017, ' Tetrazine-Responsive Self-immolative Linkers ', ChemBioChem, vol. 18, no. 1, pp. 91-95 . https://doi.org/10.1002/cbic.201600560

Molecules that undergo activation or modulation following the addition of benign external small-molecule chemical stimuli have numerous applications. Here, we report the highly efficient "decaging" of a variety of moieties by activation of a "self-im

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::10749932e3f16f50198ca484256bc7b2
https://strathprints.strath.ac.uk/64803/1/Neumann_etal_Chembiochem_2016_Tetrazine_responsive_self_immolative_linkers.pdf

Ultrastructural markers of quality in human mature oocytes vitrified using cryoleaf and cryoloop

Autor: Giovanni Coticchio, Raffaella Sciajno, M. Maione, Giulia Scaravelli, Guido Macchiarelli, Andrea Borini, Alessia Gambardella, Stefania A. Nottola, Serena Bianchi

This study describes and compares the possible effects of vitrification on the ultrastructural morphology of 20 human mature oocytes vitrified using two different supports, cryoleaf (n = 10) and cryoloop (n = 10). Fresh human mature oocytes (n = 15)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99ceab03fad374800aef4e29f9f40dca
http://hdl.handle.net/11573/40171

Vitrification may increase the rate of chromosome misalignment in the metaphase II spindle of human mature oocytes

Autor: Andrea Borini, Giovanni Coticchio, David F. Albertini, Giulia Scaravelli, Alessia Gambardella, John J. Bromfield, Raffaella Sciajno

Publikováno v: Scopus-Elsevier

The metaphase II (MII) spindle of the human oocyte may be damaged by cryopreservation. High performance confocal microscopy was used to assess meiotic spindle and chromosome organization in oocytes after vitrification by the cryoleaf system. Three ho

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ed57b74585ee5715b481511140cecaf
http://www.scopus.com/inward/record.url?eid=2-s2.0-73949085246&partnerID=MN8TOARS