A LexAop > UAS > QUAS trimeric plasmid to generate inducible and interconvertible Drosophila overexpression transgenes

Autor: Franz Wendler, Sangbin Park, Claire Hill, Alessia Galasso, Kathleen R. Chang, Iman Awan, Yulia Sudarikova, Mar Bustamante-Sequeiros, Sichen Liu, Ethan Y-H. Sung, Gabrielle Aisa-Bonoko, Seung K. Kim, Luis A. Baena-Lopez

Publikováno v: Scientific Reports, Vol 12, Iss 1, Pp 1-10 (2022)

Abstract The existence of three independent binary systems for conditional gene expression (Gal4/UAS; LexA/LexAop; QF/QUAS) has greatly expanded versatile genetic analyses in the Drosophila melanogaster; however, the experimental application of these

Externí odkaz: https://doaj.org/article/a91039c0a3d9432285cd75cd7cd85a5c

Non‐apoptotic caspase activation ensures the homeostasis of ovarian somatic stem cells

Autor: Alessia Galasso, Derek Cui Xu, Claire Hill, Daria Iakovleva, Maria Irina Stefana, Luis Alberto Baena‐Lopez

Publikováno v: Galasso, A, Xu, D C, Hill, C, Iakovleva, D, Stefana, M I & Baena-Lopez, L A 2023, ' Non-apoptotic caspase activation ensures the homeostasis of ovarian somatic stem cells ', EMBO Reports, vol. 2023, e51716 . https://doi.org/10.15252/embr.202051716

Current evidence has associated caspase activation with the regulation of basic cellular functions without causing apoptosis. Malfunction of non-apoptotic caspase activities may contribute to specific neurological disorders, metabolic diseases, autoi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f5f525afe02b37f92f8be70905c47f53
https://pure.qub.ac.uk/en/publications/de175a9e-b724-4293-950c-5fad481053db

A toolkit to generate inducible and interconvertible Drosophila transgenes

Autor: Alessia Galasso, Luis Alberto Baena-Lopez, Iman Awan, Mar Bustamante, Claire L. Hill, Gabrielle Aisabonoko, Kathleen R. Chang, Sangbin Park, Franz Wendler, Seung K. Kim, Ethan Sung, Yulia Sudarikova, Sichen Liu

The existence of three independent binary systems for conditional gene expression (Gal4/UAS; LexA/LexAop; QF/QUAST) has greatly expanded versatile genetic analyses in the fruit fly Drosophila melanogaster; however, the experimental application of the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5e9f753c4abe8b67aa7b4829c7a548d7
https://doi.org/10.1101/2020.08.18.256461

Correlation of NM23-H1 cytoplasmic expression with metastatic stage in human prostate cancer tissue

Autor: Giancarlo Troncone, Lucia Liguori, Daniela De Martino, Massimo Zollo, Nicoletta Tata, Cristin Roma, Gianluigi Arrigoni, Giuseppe Petrosino, Francesco Chiancone, Ciro Imbimbo, Immacolata Andolfo, Alessia Galasso, Stefania Staibano, Stefano Zarrilli

Publikováno v: Naunyn-Schmiedeberg's Archives of Pharmacology
Naunyn-Schmiedeberg's Archives of Pharmacology; Vol 384

Nm23-H1 has been identified as a metastatic suppressor gene in murine melanoma cell lines. Several functions have been attributed to its activity in cancer, including a histidine kinase activity, DNA repair, and regulation of other proteins involved

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f692906d31306fa933c7059d3c2af163

The Nm23-H1–h-Prune complex in cellular physiology: a ‘tip of the iceberg’ protein network perspective

Autor: Massimo Zollo, Alessia Galasso

Publikováno v: Molecular and Cellular Biochemistry. 329:149-159

Nm23-H1 (also known as NDPKA) and h-Prune form a protein complex that is part of a little-understood protein network. Modifications of this complex correlate with cancer status. Here, we focus on the role of the Nm23-H1-h-Prune complex in cellular ph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6e1678c12688ca551e947bf5771ac81
https://doi.org/10.1007/s11010-009-0115-4