Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Alessia Di Nardo"'
Publikováno v:
JACC: Advances, Vol 3, Iss 7, Pp 101058- (2024)
Externí odkaz:
https://doaj.org/article/196b39c2cd1b481e829c97d388ebbdfe
Publikováno v:
Asian Journal of Oncology, Vol 07, Iss 02, Pp 064-075 (2021)
Introduction A retrospective clinical study was performed to identify the characteristics of patients with lung cancer treated with integrative cancer treatment in addition to conventional medicine. Materials and Methods We reviewed medical records f
Externí odkaz:
https://doaj.org/article/08701a92a65a4ca4baec03ae185ac0e1
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100189- (2020)
Summary: Genetic manipulations of dissociated rodent neurons provide translatable in vitro models for disease-driven phenotypes. Cilia are cellular antenna with a role in neuronal maturation and function often perturbed in neurodevelopmental disorder
Externí odkaz:
https://doaj.org/article/88c69fa36ccf4419b9943236f69196ba
Autor:
Darius Ebrahimi-Fakhari, Afshin Saffari, Lara Wahlster, Alessia Di Nardo, Daria Turner, Tommy L. Lewis Jr., Christopher Conrad, Jonathan M. Rothberg, Jonathan O. Lipton, Stefan Kölker, Georg F. Hoffmann, Min-Joon Han, Franck Polleux, Mustafa Sahin
Publikováno v:
Cell Reports, Vol 17, Iss 4, Pp 1053-1070 (2016)
Tuberous sclerosis complex (TSC) is a neurodevelopmental disease caused by TSC1 or TSC2 mutations and subsequent activation of the mTORC1 kinase. Upon mTORC1 activation, anabolic metabolism, which requires mitochondria, is induced, yet at the same ti
Externí odkaz:
https://doaj.org/article/5ed8e2bf932447198481e0e69bebd50d
Autor:
Paivi M. Ullner, Alessia Di Nardo, James E. Goldman, Scott Schobel, Hong Yang, Kristin Engelstad, Dong Wang, Mustafa Sahin, Darryl C. De Vivo
Publikováno v:
Neurobiology of Disease, Vol 36, Iss 1, Pp 60-69 (2009)
Glucose transporter type 1 (Glut-1) facilitates glucose flux across the blood–brain-barrier. In humans, Glut-1 deficiency causes acquired microcephaly, seizures and ataxia, which are recapitulated in our Glut-1 haploinsufficient mouse model. Postna
Externí odkaz:
https://doaj.org/article/96fd1112a1d34ceba6539a952fde12f8
Autor:
Alessia Di Nardo, Leslie Louvelle, David A. Romero, Matthew Doyle, Thomas L. Forbes, Cristina H. Amon
Publikováno v:
Annals of Biomedical Engineering.
Autor:
Michela Fagiolini, Alina Rühmkorf, Ashton Brennecke, Mustafa Sahin, Patricia Award, Alessia Di Nardo
Publikováno v:
Neuroscience research. 176
CDKL5 Deficiency Disorder (CDD) is a severe encephalopathy characterized by intractable epilepsy, infantile spasms, and cognitive disabilities. The detrimental CNS manifestations and lack of therapeutic interventions represent unmet needs, necessitat
Publikováno v:
STAR Protocols, Vol 1, Iss 3, Pp 100189-(2020)
STAR Protocols
STAR Protocols
Summary Genetic manipulations of dissociated rodent neurons provide translatable in vitro models for disease-driven phenotypes. Cilia are cellular antenna with a role in neuronal maturation and function often perturbed in neurodevelopmental disorders
Autor:
Kellen D. Winden, Pooja Venugopal, Ebru Ercan-Herbst, Mustafa Sahin, Mónica Bettencourt-Dias, Alina Rühmkorf, Carla A.M. Lopes, Robin J. Kleiman, Meera E. Modi, Lee Barrett, Isadora Lenoël, Robert Behne, Alessia Di Nardo
Publikováno v:
Cell reports
SUMMARY Tuberous sclerosis complex (TSC) is a neurogenetic disorder that leads to elevated mechanistic targeting of rapamycin complex 1 (mTORC1) activity. Cilia can be affected by mTORC1 signaling, and ciliary deficits are associated with neurodevelo
Autor:
Alessia Di Nardo, Mustafa Sahin
Publikováno v:
Neuron. 99(1)
Somatic mutation of the MTOR gene is a genetic etiology of focal malformations of cortical development. In this issue of Neuron, Park et al. (2018) identify defective autophagy-dependent ciliogenesis/Wnt signaling as an underlying mechanism affecting