Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Alessia Bignucolo"'
Autor:
Massimiliano Berretta, Daniele Garozzo, Calogero Foti, Mario Roselli, Marco Materazzo, Giulia Vita, Ferdinando Iellamo, Marco Scordari, Giordana Di Mauro, Giovanna Spatari, Alessandro Ottaiano, Annalisa Noce, Marco Pellicciaro, Alessia Bignucolo, Gianluca Vanni, Oreste Claudio Buonomo
Publikováno v:
Frontiers in Oncology, Vol 14 (2024)
BackgroundImproving prognosis of BC patients has drawn the attention of health care professionals on disease related long-term side effects and on the multiple treatments BC patients must undergo. Despite advances in procedures, surgery still has mul
Externí odkaz:
https://doaj.org/article/0d588f8074c34f37ba8f7e780e2da356
Autor:
Alessandro Ottaiano, Maria Lucia Iacovino, Mariachiara Santorsola, Sergio Facchini, Domenico Iervolino, Francesco Perri, Guglielmo Nasti, Vincenzo Quagliariello, Nicola Maurea, Andrea Ronchi, Bianca Arianna Facchini, Alessia Bignucolo, Massimiliano Berretta
Publikováno v:
Journal of Translational Medicine, Vol 22, Iss 1, Pp 1-12 (2024)
Abstract Background Vitamin D (VD) is implicated in various health conditions, including colorectal cancer (CRC). To investigate potential relationships between pre-chemotherapy VD levels and the time-to-outcome in metastatic CRC patients, we conduct
Externí odkaz:
https://doaj.org/article/23e608415232430c876e0f269c4ce34a
Autor:
Vasileios Fragoulakis, Rossana Roncato, Alessia Bignucolo, George P. Patrinos, Giuseppe Toffoli, Erika Cecchin, Christina Mitropoulou
Publikováno v:
Pharmacological Research, Vol 197, Iss , Pp 106949- (2023)
Objectives: A cost-utility analysis was conducted to evaluate pharmacogenomic (PGx)-guided treatment compared to the standard-of-care intervention among patients diagnosed with colorectal cancer (CRC) in Italy. Methods: Data derived from a prospectiv
Externí odkaz:
https://doaj.org/article/2185e784911e4a6d95a70081b5644be6
Autor:
Giovanni Canil, Marco Orleni, Bianca Posocco, Sara Gagno, Alessia Bignucolo, Marcella Montico, Rossana Roncato, Serena Corsetti, Michele Bartoletti, Giuseppe Toffoli
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1524 (2023)
Poly (ADP-ribose) polymerase inhibitors (PARPis) are becoming increasingly meaningful in oncology, and their therapeutic drug monitoring (TDM) might be beneficial for patients. Several bioanalytical methods have been reported for PARPis quantificatio
Externí odkaz:
https://doaj.org/article/82a9804b71874c398521fae501f99ab9
Autor:
Elena De Mattia, Vincenzo Canzonieri, Jerry Polesel, Silvia Mezzalira, Chiara Dalle Fratte, Eva Dreussi, Rossana Roncato, Alessia Bignucolo, Roberto Innocente, Claudio Belluco, Salvatore Pucciarelli, Antonino De Paoli, Elisa Palazzari, Giuseppe Toffoli, Erika Cecchin
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Identifying patients at risk of poor response to neoadjuvant chemoradiotherapy (nCRT) is an emerging clinical need in locally advanced rectal cancer (LARC). SMAD3 is a key player in the chemoradio-resistance phenotype and its expression is both const
Externí odkaz:
https://doaj.org/article/806049ad1c0d4ec6ba37193de978c2fb
Publikováno v:
Pharmaceutics, Vol 14, Iss 11, p 2468 (2022)
Pharmacogenetics plays a key role in personalized cancer treatment. Currently, the clinically available pharmacogenetic markers for metastatic colorectal cancer (mCRC) are in genes related to drug metabolism, such as DPYD for fluoropyrimidines and UG
Externí odkaz:
https://doaj.org/article/6f07011db1694105a85c6b8f9a33b9c7
Autor:
Massimiliano Berretta, Vincenzo Quagliariello, Alessia Bignucolo, Sergio Facchini, Nicola Maurea, Raffaele Di Francia, Francesco Fiorica, Saman Sharifi, Silvia Bressan, Sara N. Richter, Valentina Camozzi, Luca Rinaldi, Carla Scaroni, Monica Montopoli
Publikováno v:
Antioxidants, Vol 11, Iss 6, p 1090 (2022)
Background: Vitamin D exerts multiple beneficial effects in humans, including neuronal, immune, and bone homeostasis and the regulation of cardiovascular functions. Recent studies correlate vitamin D with cancer cell growth and survival, but meta-ana
Externí odkaz:
https://doaj.org/article/00fa883679df4e81b87a79205c435441
Autor:
Alessia Bignucolo, Lucia Scarabel, Silvia Mezzalira, Jerry Polesel, Erika Cecchin, Giuseppe Toffoli
Publikováno v:
Vaccines, Vol 9, Iss 8, p 825 (2021)
Sex differences in adaptive and innate immune responses have been shown to occur and anecdotal reports suggest that vaccine efficacy and safety may be sex-dependent. We investigated the influence of sex on the efficacy of COVID-19 vaccines through a
Externí odkaz:
https://doaj.org/article/0655f7f408254e73b3b79293479e499b
Autor:
Elena De Mattia, Jerry Polesel, Rossana Roncato, Adrien Labriet, Alessia Bignucolo, Eva Dreussi, Loredana Romanato, Michela Guardascione, Angela Buonadonna, Mario D'Andrea, Eric Lévesque, Derek Jonker, Félix Couture, Chantal Guillemette, Erika Cecchin, Giuseppe Toffoli
Publikováno v:
Frontiers in Oncology, Vol 9 (2019)
Nuclear receptors act as mediators of cancer-related inflammation and gene expression. They have a regulatory effect on genes encoding proteins related to drug adsorption, distribution, metabolism, and excretion. The aim of the present study was to h
Externí odkaz:
https://doaj.org/article/33bf59e066744d10896b27f28e166d32
Autor:
Elena De Mattia, Erika Cecchin, Marcella Montico, Adrien Labriet, Chantal Guillemette, Eva Dreussi, Rossana Roncato, Alessia Bignucolo, Angela Buonadonna, Mario D’Andrea, Luigi Coppola, Sara Lonardi, Eric Lévesque, Derek Jonker, Félix Couture, Giuseppe Toffoli
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Pharmacogenomics has largely been applied to the personalization of irinotecan-based treatment, focusing mainly on the study of genetic variants in adsorption, distribution, metabolism, and excretion (ADME) genes. The transcriptional control of ADME
Externí odkaz:
https://doaj.org/article/5a272cbd41064de99f177ebd64e1f2a8