Zobrazeno 1 - 10
of 148
pro vyhledávání: '"Alessia Bertamino"'
Autor:
Ilaria Capolupo, Maria Rosaria Miranda, Simona Musella, Veronica Di Sarno, Michele Manfra, Carmine Ostacolo, Alessia Bertamino, Pietro Campiglia, Tania Ciaglia
Publikováno v:
Antioxidants, Vol 13, Iss 11, p 1284 (2024)
The endoplasmic reticulum (ER) is the organelle mainly involved in maintaining cellular homeostasis and driving correct protein folding. ER-dependent defects or dysfunctions are associated with the genesis/progression of several pathological conditio
Externí odkaz:
https://doaj.org/article/feb65dfa503b41549fc9c54042e547b0
Autor:
Rita Turcio, Francesca Di Matteo, Ilaria Capolupo, Tania Ciaglia, Simona Musella, Carla Di Chio, Claudio Stagno, Pietro Campiglia, Alessia Bertamino, Carmine Ostacolo
Publikováno v:
Marine Drugs, Vol 22, Iss 8, p 350 (2024)
Bioactive compounds are abundant in animals originating from marine ecosystems. Ion channels, which include sodium, potassium, calcium, and chloride, together with their numerous variants and subtypes, are the primary molecular targets of the latter.
Externí odkaz:
https://doaj.org/article/5a0257501d444c2c9cd23465758cfb2f
Autor:
Francesca Di Matteo, Francesca Mancuso, Rita Turcio, Tania Ciaglia, Claudio Stagno, Carla Di Chio, Pietro Campiglia, Alessia Bertamino, Salvatore Vincenzo Giofrè, Carmine Ostacolo, Nunzio Iraci
Publikováno v:
Molecules, Vol 29, Iss 12, p 2940 (2024)
Potassium channels have recently emerged as suitable target for the treatment of epileptic diseases. Among potassium channels, KCNT1 channels are the most widely characterized as responsible for several epileptic and developmental encephalopathies. N
Externí odkaz:
https://doaj.org/article/a8ece3bfd3c04e12bd279b9e1518a461
Autor:
Mauro De Nisco, Antonio Di Maio, Michele Manfra, Carmine Ostacolo, Alessia Bertamino, Pietro Campiglia, Isabel M. Gomez-Monterrey, Silvana Pedatella
Publikováno v:
Reactions, Vol 3, Iss 1, Pp 192-202 (2022)
The selective N-4 alkylation of cytosine plays a critical role in the synthesis of biologically active molecules. This work focuses on the development of practical reaction conditions toward a regioselective synthesis of N-4-alkyl cytosine derivative
Externí odkaz:
https://doaj.org/article/bca17307f62047deb8adf99605eed053
Autor:
Tania Ciaglia, Vincenzo Vestuto, Alessia Bertamino, Rosario González-Muñiz, Isabel Gómez-Monterrey
Publikováno v:
Frontiers in Oncology, Vol 12 (2023)
The transient melastatin receptor potential (TRPM) ion channel subfamily functions as cellular sensors and transducers of critical biological signal pathways by regulating ion homeostasis. Some members of TRPM have been cloned from cancerous tissues,
Externí odkaz:
https://doaj.org/article/c4bca2cd14994b09b989c3cac6fc6245
Autor:
Marzia Di Donato, Carmine Ostacolo, Pia Giovannelli, Veronica Di Sarno, Isabel M. Gomez Monterrey, Pietro Campiglia, Antimo Migliaccio, Alessia Bertamino, Gabriella Castoria
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Transient receptor potential melastatin-8 (TRPM8) represents an emerging target in prostate cancer, although its mechanism of action remains unclear. Here, we have characterized and investigated the effects of TRPM8 modulators in prostate ca
Externí odkaz:
https://doaj.org/article/fa3e2cc22ff64f05950e4e504372fb1e
Autor:
Verdiana Covelli, Antonietta Cozzolino, Paola Rizzo, Manuela Rodriquez, Vincenzo Vestuto, Alessia Bertamino, Christophe Daniel, Gaetano Guerra
Publikováno v:
Molecules, Vol 28, Iss 13, p 5095 (2023)
Films and fibers of syndiotactic polystyrene (sPS), being amorphous or exhibiting nanoporous crystalline (NC) or dense crystalline phases, were loaded with salicylic acid (SA), a relevant non-volatile antimicrobial molecule. In the first section of t
Externí odkaz:
https://doaj.org/article/3424d28311e045e6af4603efc6cd0339
Autor:
Michele Ciccarelli, Daniela Sorriento, Antonella Fiordelisi, Jessica Gambardella, Antonietta Franco, Carmine delGiudice, Marina Sala, Maria Gaia Monti, Alessia Bertamino, Pietro Campiglia, Marco Oliveti, Paolo Poggio, Giovanna Trinchese, Gina Cavaliere, Ersilia Cipolletta, Maria Pina Mollica, Domenico Bonaduce, Bruno Trimarco, Guido Iaccarino
Publikováno v:
ESC Heart Failure, Vol 7, Iss 4, Pp 1571-1584 (2020)
Abstract Aims The effects of GRK2 inhibition on myocardial metabolism in heart failure (HF) are unchartered. In this work, we evaluated the impact of pharmacological inhibition of GRK2 by a cyclic peptide, C7, on metabolic, biochemical, and functiona
Externí odkaz:
https://doaj.org/article/e81b5044fb7e45569835835d35abf720
Autor:
Vincenzo Vestuto, Giuseppina Amodio, Giacomo Pepe, Manuela Giovanna Basilicata, Raffaella Belvedere, Enza Napolitano, Daniela Guarnieri, Valentina Pagliara, Simona Paladino, Manuela Rodriquez, Alessia Bertamino, Pietro Campiglia, Paolo Remondelli, Ornella Moltedo
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 2009 (2022)
Parkinson’s disease (PD) represents one of the most common neurodegenerative disorders, characterized by a dopamine (DA) deficiency in striatal synapses and misfolded toxic α-synuclein aggregates with concomitant cytotoxicity. In this regard, the
Externí odkaz:
https://doaj.org/article/8273afd6b2414f98a31c9f0baef5e4d5
Autor:
Eduardo Sommella, Emanuela Salviati, Vicky Caponigro, Manuela Grimaldi, Simona Musella, Alessia Bertamino, Luigi Cacace, Remo Palladino, Giuseppe Di Mauro, Federico Marini, Anna Maria D’Ursi, Pietro Campiglia
Publikováno v:
Metabolites, Vol 12, Iss 6, p 530 (2022)
Salivary gland tumors are relatively uncommon neoplasms that represent less than 5% of head and neck tumors, and about 90% are in the parotid gland. The wide variety of histologies and tumor characteristics makes diagnosis and treatment challenging.
Externí odkaz:
https://doaj.org/article/8826a8d215a04c43be6a15c65269b6f6