Zobrazeno 1 - 10
of 235
pro vyhledávání: '"Alessia, Pascale"'
Autor:
Valeria Cavalloro, Nicoletta Marchesi, Pasquale Linciano, Daniela Rossi, Lucrezia Irene Maria Campagnoli, Alice Fossati, Karzan Mahmood Ahmed, Alessio Malacrida, Mariarosaria Miloso, Giuseppe Mazzeo, Sergio Abbate, Giovanna Longhi, Francesca Alessandra Ambrosio, Giosuè Costa, Stefano Alcaro, Alessia Pascale, Emanuela Martino, Simona Collina
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The number of patients affected by neurodegenerative diseases is increasing worldwide, and no effective treatments have been developed yet. Although precision medicine could represent a powerful tool, it remains a challenge due to the high variabilit
Externí odkaz:
https://doaj.org/article/8a9c141f46a34f9d930022895ebcf63d
Autor:
Sonia La Cognata, Donatella Armentano, Nicoletta Marchesi, Pietro Grisoli, Alessia Pascale, Marion Kieffer, Angelo Taglietti, Anthony P. Davis, Valeria Amendola
Publikováno v:
Chemistry, Vol 4, Iss 3, Pp 855-864 (2022)
Considering the wide interest in (benz)imidazolium-based drugs, we here report our study on a benzimidazolium-based organic cage as potential antimicrobial and antifungal agent. Cytotoxicity studies on a human derived cell line, SH-SY5Y, showed that
Externí odkaz:
https://doaj.org/article/2eedbe9ae8554c8db8a606d11c2be657
Autor:
Cristiana Pistono, Cecilia Osera, Maria Cristina Monti, Chiara Boiocchi, Giulia Mallucci, Mariaclara Cuccia, Cristina Montomoli, Roberto Bergamaschi, Alessia Pascale
Publikováno v:
Immuno, Vol 2, Iss 3, Pp 469-481 (2022)
Multiple sclerosis (MS) is a multifactorial neurodegenerative disease. Low levels of vitamin D are a risk factor for MS and alterations in the vitamin D receptor (VDR) might be a risk factor as well. This study aimed to evaluate whether the VDR rs731
Externí odkaz:
https://doaj.org/article/99046fa25177484889ac2a61fe9d8592
Autor:
Angelica Varesi, Lucrezia Irene Maria Campagnoli, Salvatore Chirumbolo, Beatrice Candiano, Adelaide Carrara, Giovanni Ricevuti, Ciro Esposito, Alessia Pascale
Publikováno v:
Pharmacological Research, Vol 192, Iss , Pp 106799- (2023)
Depression is the most prevalent mental disorder in the world associated with huge socio-economic consequences. While depressive-related symptoms are well known, the molecular mechanisms underlying disease pathophysiology and progression remain large
Externí odkaz:
https://doaj.org/article/115ea0176a5a49d388b39e3862b9a56f
Autor:
Nicoletta Marchesi, Foroogh Fahmideh, Annalisa Barbieri, Marco Racchi, Alessia Pascale, Stefano Govoni
Publikováno v:
Frontiers in Drug Safety and Regulation, Vol 2 (2022)
Medical Devices Made of Substances (MDMS) are increasingly used in the healthcare system alongside classic medicinal products and constitute an important field of experimentation and innovation in the biomedical field. In fact, these products are rap
Externí odkaz:
https://doaj.org/article/ec5d5a3144ec4953b18b8ca442bbadc7
Autor:
Angelica Varesi, Lucrezia Irene Maria Campagnoli, Adelaide Carrara, Ilaria Pola, Elena Floris, Giovanni Ricevuti, Salvatore Chirumbolo, Alessia Pascale
Publikováno v:
Antioxidants, Vol 12, Iss 1, p 180 (2023)
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive memory loss and cognitive decline. Although substantial research has been conducted to elucidate the complex pathophysiology of AD, the therapeutic approach still
Externí odkaz:
https://doaj.org/article/0fddcef7945841b799126588dd99a1a5
Autor:
Katarzyna Pawletko, Halina Jędrzejowska-Szypułka, Katarzyna Bogus, Alessia Pascale, Foroogh Fahmideh, Nicoletta Marchesi, Aniela Grajoszek, Edyta Olakowska, Jarosław Jerzy Barski
Publikováno v:
Brain Sciences, Vol 12, Iss 12, p 1671 (2022)
The animal thromboembolic model of ischemia perfectly mimics human ischemic stroke which remains the leading cause of disability and mortality in humans. The development of new treatment strategies was therefore imperative. The purpose of this study
Externí odkaz:
https://doaj.org/article/c4cb6df85d904665b24a94b1cde40166
Autor:
Claudio Bucolo, Annalisa Barbieri, Ilaria Viganò, Nicoletta Marchesi, Francesco Bandello, Filippo Drago, Stefano Govoni, Gianpaolo Zerbini, Alessia Pascale
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
To investigate the role of vascular endothelial growth factor (VEGF) at different phases of diabetic retinopathy (DR), we assessed the retinal protein expression of VEGF-A164 (corresponding to the VEGF165 isoform present in humans, which is the predo
Externí odkaz:
https://doaj.org/article/2c90abd8c3a84f08b0d5f8deab25fd78
Autor:
Lucrezia Irene Maria Campagnoli, Nicoletta Marchesi, Mariapia Vairetti, Alessia Pascale, Andrea Ferrigno, Annalisa Barbieri
Publikováno v:
Cells, Vol 11, Iss 18, p 2827 (2022)
Human aging, a natural process characterized by structural and physiological changes, leads to alterations of homeostatic mechanisms, decline of biological functions, and subsequently, the organism becomes vulnerable to external stress or damage. In
Externí odkaz:
https://doaj.org/article/4406394dce1046e6b1098a3c53e18785
Autor:
Angelica Varesi, Salvatore Chirumbolo, Lucrezia Irene Maria Campagnoli, Elisa Pierella, Gaia Bavestrello Piccini, Adelaide Carrara, Giovanni Ricevuti, Catia Scassellati, Cristian Bonvicini, Alessia Pascale
Publikováno v:
Antioxidants, Vol 11, Iss 7, p 1224 (2022)
Cellular senescence is an irreversible state of cell cycle arrest occurring in response to stressful stimuli, such as telomere attrition, DNA damage, reactive oxygen species, and oncogenic proteins. Although beneficial and protective in several physi
Externí odkaz:
https://doaj.org/article/3b9239e8212342e6bac8c1d5118e6069