LINE-1 regulates cortical development by acting as long non-coding RNAs

Autor: Damiano Mangoni, Alessandro Simi, Pierre Lau, Alexandros Armaos, Federico Ansaloni, Azzurra Codino, Devid Damiani, Lavinia Floreani, Valerio Di Carlo, Diego Vozzi, Francesca Persichetti, Claudio Santoro, Luca Pandolfini, Gian Gaetano Tartaglia, Remo Sanges, Stefano Gustincich

Publikováno v: Nature Communications, Vol 14, Iss 1, Pp 1-14 (2023)

Abstract Long Interspersed Nuclear Elements-1s (L1s) are transposable elements that constitute most of the genome’s transcriptional output yet have still largely unknown functions. Here we show that L1s are required for proper mouse brain corticoge

Externí odkaz: https://doaj.org/article/66f2f44858894eb082807efecd36e486

The Pgbd5 DNA transposase is required for mouse cerebral cortex development through DNA double-strand breaks formation

Autor: Alessandro Simi, Federico Ansaloni, Devid Damiani, Azzurra Codino, Damiano Mangoni, Pierre Lau, Diego Vozzi, Luca Pandolfini, Remo Sanges, Stefano Gustincich

Transposons are conserved mobile genetic elements and one of the major sources of genetic variability during organisms’ evolution. PiggyBac Transposable Element Derived 5 (Pgbd5), an evolutionarily conserved vertebrate DNA transposase-coding gene,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::122e383763554ddbe4029745d89903d3
https://doi.org/10.1101/2023.05.09.539730

3D Underground Mapping with a Mobile Robot and a GPR Antenna

Autor: Alessandro Simi, Evangelos Skartados, Ioannis Kotavelis, Guido Manacorda, Dimitrios Tzovaras, Georgios Kouros, Dimitrios Giakoumis

Publikováno v: IROS

Automatic subsurface mapping is essential in the construction services, as it is anticipated to become the main operational environment of the future robots to be realized in the respective domain. Towards this direction, the paper at hand, introduce

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f382d1e8c157ffa97b9e7d05beb98213

High-density dual-polarized GPR array for underground asset mapping

Autor: Guido Manacorda, Alessandro Simi, Davide Pasculli, Fabio Giannino

Publikováno v: 2017 9th International Workshop on Advanced Ground Penetrating Radar (IWAGPR).

GPR is one of the most reliable instruments to obtain information on subsoil utilities and since its diffusion many efforts have been made in order to reduce the effect of the “human factor” during the data interpretation phase, and to maximize t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7a80a4e332597c3be8cc41bd19729a53
https://doi.org/10.1109/iwagpr.2017.7996080

Electrical coupling of mammalian neurons to microelectrodes with 3D nanoprotrusions

Autor: Luca Berdondini, Luigi Martiradonna, Luca Quarta, Alessandro Simi, Massimo De Vittorio, Leonardo Sileo, Alessandro Maccione, Ferruccio Pisanello

Publikováno v: Microelectronic engineering 111 (2013): 384–390. doi:10.1016/j.mee.2013.03.152
info:cnr-pdr/source/autori:Sileo L.; Pisanello F.; Quarta L.; Maccione A.; Simi A.; Berdondini L.; Vittorio M.D.; Martiradonna L./titolo:Electrical coupling of mammalian neurons to microelectrodes with 3D nanoprotrusions/doi:10.1016%2Fj.mee.2013.03.152/rivista:Microelectronic engineering/anno:2013/pagina_da:384/pagina_a:390/intervallo_pagine:384–390/volume:111

Ion Beam Induced Deposition (IBID) is employed to fabricate three-dimensional nanoprotrusions on top of the recording pads of an active pixel sensor array (APS-MEA) featuring 4096 microelectrodes. Modified APS-MEAs are envisioned as enhanced tools to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9cc210c34caf1d2dedda6bf6a89f0fb6
https://hdl.handle.net/11587/389468