Zobrazeno 1 - 10
of 318
pro vyhledávání: '"Alessandro Sgambato"'
Autor:
Antonio Agostini, Ilaria Guerriero, Geny Piro, Giuseppe Quero, Luca Roberto, Annachiara Esposito, Alessia Caggiano, Lorenzo Priori, Giulia Scaglione, Francesco De Sanctis, Antonella Sistigu, Martina Musella, Alberto Larghi, Gianenrico Rizzatti, Donatella Lucchetti, Sergio Alfieri, Alessandro Sgambato, Emilio Bria, Laura Bizzozero, Sabrina Arena, Stefano Ugel, Vincenzo Corbo, Giampaolo Tortora, Carmine Carbone
Publikováno v:
Journal of Translational Medicine, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease. This is due to its aggressive course, late diagnosis and its intrinsic drugs resistance. The complexity of the tumor, in terms of cell components and heterogeneity, has
Externí odkaz:
https://doaj.org/article/adbd2731a7444e4995e152ebaac77297
Autor:
Federica Zito Marino, Simona Buono, Marco Montella, Rosa Giannatiempo, Francesco Messina, Giovanni Casaretta, Grazia Arpino, Giulia Vita, Francesco Fiorentino, Luigi Insabato, Alessandro Sgambato, Michele Orditura, Renato Franco, Marina Accardo
Publikováno v:
The Journal of Pathology: Clinical Research, Vol 9, Iss 5, Pp 367-377 (2023)
Abstract Triple‐negative breast cancer (TNBC) is usually an aggressive disease with a poor prognosis and limited treatment options. The neurotrophic tyrosine receptor kinase (NTRK) gene fusions are cancer type‐agnostic emerging biomarkers approve
Externí odkaz:
https://doaj.org/article/92e0f09f3c1947ca80404c43828e4f6a
Autor:
Donatella Lucchetti, Francesca Luongo, Filomena Colella, Enrico Gurreri, Giulia Artemi, Claudia Desiderio, Stefano Serra, Felice Giuliante, Ruggero De Maria, Alessandro Sgambato, Alberto Vitali, Micol Eleonora Fiori
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 162, Iss , Pp 114679- (2023)
Colorectal cancer (CRC) is the second most common cause of cancer death, leading to almost 1 million deaths per year. Despite constant progress in surgical and therapeutic protocols, the 5-year survival rate of advanced CRC patients remains extremely
Externí odkaz:
https://doaj.org/article/3ab2e46a1956458eb8e1300c3a9ad3d6
Autor:
Donatella Lucchetti, Ina Valeria Zurlo, Filomena Colella, Claudio Ricciardi-Tenore, Mariantonietta Di Salvatore, Giampaolo Tortora, Ruggero De Maria, Felice Giuliante, Alessandra Cassano, Michele Basso, Antonio Crucitti, Ilaria Laurenzana, Giulia Artemi, Alessandro Sgambato
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Liquid biopsy has become a useful alternative in metastatic colorectal cancer (mCRC) patients when tissue biopsy of metastatic sites is not feasible. In this study we aimed to investigate the clinical utility of circulating exosomes DNA in t
Externí odkaz:
https://doaj.org/article/76b8a6a6c9ab48f3a5d635c255f279da
Autor:
Simona Laurino, Ludmila Carmen Omer, Francesco Albano, Graziella Marino, Antonella Bianculli, Angela Pia Solazzo, Alessandro Sgambato, Geppino Falco, Sabino Russi, Anna Maria Bochicchio
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Background and objectiveThe oncogenic effect of ionizing radiation is widely known. Sarcomas developing after radiation therapy (RT), termed “iatrogenic disease of success”, represent a growing problem, since the advancements in cancer management
Externí odkaz:
https://doaj.org/article/d9a358e31b1141f19e427e86eed7e7e2
Autor:
Fiorella D’Auria, Teodora Statuto, Luciana Rago, Antonietta Montagna, Giovanni Castaldo, Irene Schirò, Anna Zeccola, Teresa Virgilio, Gabriella Bianchino, Antonio Traficante, Alessandro Sgambato, Vincenzo Fusco, Luciana Valvano, Giovanni Calice
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Radiotherapy (RT) is an important therapeutic option in patients with localized prostate cancer (PC). Unfortunately, radiation treatment causes a decrease in peripheral lymphocytes and, consequently, influences the patients’ immune status. Our aim
Externí odkaz:
https://doaj.org/article/b51605b4adc94411a52faf8538e17f23
Autor:
Tiziana Servidei, Alessandro Sgambato, Donatella Lucchetti, Pierluigi Navarra, Antonio Ruggiero
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 4, p 77 (2023)
Tumors of the Central Nervous System (CNS) represent the leading cause of cancer-related deaths in children. Current treatment options are not curative for most malignant histologies, and intense preclinical and clinical research is needed to develop
Externí odkaz:
https://doaj.org/article/3ab63a4bfa54430f8c12f7f8b86de22f
Autor:
Stefania Trino, Ilaria Laurenzana, Daniela Lamorte, Giovanni Calice, Angelo De Stradis, Michele Santodirocco, Alessandro Sgambato, Antonella Caivano, Luciana De Luca
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Acute myeloid leukemia (AML) is an aggressive and heterogeneous clonal disorder of hematopoietic stem/progenitor cells (HSPCs). It is not well known how leukemia cells alter hematopoiesis promoting tumor growth and leukemic niche formation. In this s
Externí odkaz:
https://doaj.org/article/074195e5778a43c6b0b18a2aa01c71f3
Autor:
Ilaria Laurenzana, Stefania Trino, Daniela Lamorte, Angelo De Stradis, Michele Santodirocco, Alessandro Sgambato, Luciana De Luca, Antonella Caivano
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Multiple myeloma (MM) is characterized by the abnormal proliferation of clonal plasma cells (PCs) in bone marrow (BM). MM-PCs progressively occupy and likely alter BM niches where reside hematopoietic stem and progenitor cells (HSPCs) whose viability
Externí odkaz:
https://doaj.org/article/2be9b3cdf19d4cf38f5a5b6675761815
Autor:
Nicola Silvestris, Giovanni Apolone, Gerardo Botti, Gennaro Ciliberto, Massimo Costantini, Paolo De Paoli, Silvia Franceschi, Giuseppe Opocher, Angelo Paradiso, Paolo Pronzato, Alessandro Sgambato, Ruggero De Maria
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-4 (2020)
Abstract If we focus our attention on seven main features of COVID-19 infection (heterogeneity, fragility, lack of effective treatments and vaccines, “miraculous cures”, psychological suffering, deprivation, and globalization), we may establish p
Externí odkaz:
https://doaj.org/article/64a8f119d6e4448c92f11f5a7547340f