Zobrazeno 1 - 10
of 63
pro vyhledávání: '"Alessandro S. Nascimento"'
Autor:
Lorenzo Briganti, Caio Capetti, Vanessa O.A. Pellegrini, Silvina Ghio, Eleonora Campos, Alessandro S. Nascimento, Igor Polikarpov
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1557-1566 (2021)
Glycoside hydrolases (GHs) are essential for plant biomass deconstruction. GH11 family consist of endo-β-1,4-xylanases which hydrolyze xylan, the second most abundant cell wall biopolymer after cellulose, into small bioavailable oligomers. Structura
Externí odkaz:
https://doaj.org/article/c86295a2c3bb499db6dc78fd59b4e5f0
Autor:
Luana G. Morão, Lívia R. Manzine, Lívia Oliveira D. Clementino, Carsten Wrenger, Alessandro S. Nascimento
Publikováno v:
PLoS ONE, Vol 17, Iss 7 (2022)
Structural biology projects are highly dependent on the large-scale expression of soluble protein and, for this purpose, heterologous expression using bacteria or yeast as host systems is usually employed. In this scenario, some of the parameters to
Externí odkaz:
https://doaj.org/article/64243c561a4940c5b8bc8a59cc225e9a
Autor:
Angélica Luana C. Barra, Najeeb Ullah, Luana G. Morão, Carsten Wrenger, Christian Betzel, Alessandro S. Nascimento
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 11 (2021)
Malaria is still today one of the most concerning diseases, with 219 million infections in 2019, most of them in Sub-Saharan Africa and Latin America, causing approx. 409,000 deaths per year. Despite the tremendous advances in malaria treatment and p
Externí odkaz:
https://doaj.org/article/142de2c672fc4097947e4300984161a8
Autor:
Angélica Luana C. Barra, Lívia de Oliveira C. Dantas, Luana Galvão Morão, Raíssa F. Gutierrez, Igor Polikarpov, Carsten Wrenger, Alessandro S. Nascimento
Publikováno v:
Frontiers in Public Health, Vol 8 (2020)
Antibiotic resistance is a worldwide concern that requires a concerted action from physicians, patients, governmental agencies, and academia to prevent infections and the spread of resistance, track resistant bacteria, improve the use of current anti
Externí odkaz:
https://doaj.org/article/3767c1e3fe3b44c38c83332db57df5f6
Autor:
Renata N. Florindo, Valquiria P. Souza, Hemily S. Mutti, LÃvia R. Manzine Margarido, Cesar Camilo, Sandro R. Marana, Igor Polikarpov, Alessandro S. Nascimento
Publikováno v:
Data in Brief, Vol 15, Iss , Pp 340-343 (2017)
Here the statistics concerning X-ray data processing and structure refinement are given, together with the substrate preference analysis for ThBgl1 and ThBgl2. Finally, the analysis of the influence of temperature and pH on the activities of both enz
Externí odkaz:
https://doaj.org/article/b7e90fa16300456a83b18ad374e71504
Autor:
Paulo C. T. Souza, Larissa C. Textor, Denise C. Melo, Alessandro S. Nascimento, Munir S. Skaf, Igor Polikarpov
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-11 (2017)
Abstract The natural ligand 17β-estradiol (E2) is so far believed to induce a unique agonist-bound active conformation in the ligand binding domain (LBD) of the estrogen receptors (ERs). Both subtypes, ERα and ERβ, are transcriptionally activated
Externí odkaz:
https://doaj.org/article/7658c3e0f2b849b89a16ce660fd83156
Publikováno v:
Frontiers in Molecular Biosciences, Vol 6 (2019)
The precise modeling of molecular interactions remains an important goal among molecular modeling techniques. Some of the challenges in the field include the precise definition of a Hamiltonian for biomolecular systems, together with precise paramete
Externí odkaz:
https://doaj.org/article/7a67d210beb145829b8d3494382f07d6
Publikováno v:
Acta Crystallographica Section E, Vol 69, Iss 7, Pp o1083-o1084 (2013)
In the title compound, C15H11BrN4O2S, the tetrazole ring makes dihedral angles of 45.97 (10) and 75.41 (1)°, respectively, with the benzoyl and bromobenzene rings while the dihedral angle between the benzene rings is 73.77 (1)°. In the crystal, mol
Externí odkaz:
https://doaj.org/article/5ab223bbddbc4539821ade23b74698b9
Autor:
Adriano de Freitas Fernandes, Diego Antonio Leonardo, Italo Augusto Cavini, Higor Vinícius Dias Rosa, Jhon Antoni Vargas, Humberto D'Muniz Pereira, Alessandro S. Nascimento, Richard Charles Garratt
Publikováno v:
Cytoskeleton (Hoboken)
Septins possess a conserved guanine nucleotide-binding (G) domain that participates in the stabilization of organized hetero-oligomeric complexes which assemble into filaments, rings and network-like structures. The fruit fly, Drosophila melanogaster
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7c90d845a124b9ea9dc76c736487555
https://doi.org/10.1002/cm.21740
https://doi.org/10.1002/cm.21740
Publikováno v:
Computational Biology and Chemistry. 103:107830
The correct evaluation of ligand binding free energies by computational methods is still a very challenging active area of research. The most employed methods for these calculations can be roughly classified into four groups: (i) the fastest and less
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8333290954f3bbb9017cccf87f683253
https://doi.org/10.1016/j.compbiolchem.2023.107830
https://doi.org/10.1016/j.compbiolchem.2023.107830