Inhibition of noradrenergic signalling in rodent orbitofrontal cortex impairs the updating of goal-directed actions

Autor: Alessandro Piccin, Juan Carlos Cerpa, Margot Dehove, Marina Lavigne, Eric J Kremer, Mathieu Wolff, Shauna L Parkes, Etienne Coutureau

Publikováno v: eLife. 12

In a constantly changing environment, organisms must track the current relationship between actions and their specific consequences and use this information to guide decision-making. Such goal-directed behaviour relies on circuits involving cortical

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::95eadd52201a9ed0a698a357b592244e
https://doi.org/10.7554/elife.81623

Noradrenergic signaling in the rodent orbitofrontal cortex is required to update goal-directed actions

Autor: Juan-Carlos Cerpa, Alessandro Piccin, Margot Dehove, Marina Lavigne, Eric J. Kremer, Mathieu Wolff, Shauna L. Parkes, Etienne Coutureau

SUMMARYIn a constantly changing environment, organisms must track the current relationship between actions and their specific consequences and use this information to guide decision-making. Such goal-directed behavior relies on circuits involving cor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::3924427fe967ee4e3450db31c859d3de
https://doi.org/10.1101/2022.06.30.498245

Sex‐linked roles of the CRF 1 and the CRF 2 receptor in social behavior

Autor: Alessandro Piccin, Angelo Contarino

Publikováno v: Journal of Neuroscience Research. 98:1561-1574

Dysfunctional social behavior is a major clinical feature of mood, anxiety, autism spectrum, and substance-related disorders, and may dramatically contribute to the poor outcome of these diseases. Nevertheless, the mechanisms underlying social behavi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::63ca7b39c7d67dd5f6d1f27c7ea83583
https://doi.org/10.1002/jnr.24629

Involvement of Autophagy in Levodopa‐Induced Dyskinesia

Autor: Carina Plewnia, Lidia Urbina, David Sulzer, Erwan Bezard, Mikael Altun, Michael Feyder, Benjamin Dehay, Anders Borgkvist, Per Nilsson, Qin Li, Giada Spigolon, Emanuela Santini, Alessandro Piccin, Gilberto Fisone, Ori J. Lieberman

Publikováno v: Movement Disorders
Movement Disorders, Wiley, 2021, Online ahead of print. ⟨10.1002/mds.28480⟩
Movement Disorders, 2021, Online ahead of print. ⟨10.1002/mds.28480⟩

Background Autophagy is intensively studied in cancer, metabolic and neurodegenerative diseases, but little is known about its role in pathological conditions linked to altered neurotransmission. We examined the involvement of autophagy in levodopa (

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db06734382d3407f323778ea9b5f0938
https://www.hal.inserm.fr/inserm-03114552/document

The CRF

Autor: Alessandro, Piccin, Angelo, Contarino

Publikováno v: Journal of neuroscience researchREFERENCES. 100(1)

Poor sociability and aggressive behavior are key clinical features of opioid use disorders. The corticotropin-releasing factor (CRF) system may mediate behavioral effects of substances of abuse but its implication in substance-induced social behavior

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::a8bf73b7ae0f37d53a3c8eed6aab4994
https://pubmed.ncbi.nlm.nih.gov/32725663