Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Alessandro Malara"'
Autor:
Alessandro Malara, Vittorio Abbonante, Francesca Rossella Calledda, Daniele Capitanio, Daniele Cattaneo, Alessandra Iurlo, Cecilia Gelfi, Alessandra Balduini
Publikováno v:
HemaSphere, Vol 7, p e440963f (2023)
Externí odkaz:
https://doaj.org/article/9559fb997f5d411aad017d1305dca52b
Autor:
Alessandro Malara, Cristian Gruppi, Margherita Massa, Maria Enrica Tira, Vittorio Rosti, Alessandra Balduini, Giovanni Barosi
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
In primary myelofibrosis, extra-domain A fibronectin (EDA-FN), the result of alternative splicing of FN gene, sustains megakaryocyte proliferation and confers a pro-inflammatory phenotype to bone marrow cell niches. In this work we assessed the level
Externí odkaz:
https://doaj.org/article/03552c1d9dfd4d5d86589d2e741d6f83
Autor:
Leonardo Sandrini, Patrizia Amadio, Alessandro Ieraci, Alessandro Malara, José P. Werba, Paolo M. Soprano, Alessandra Balduini, Marta Zarà, Alice Bonomi, Fabrizio Veglia, Gualtiero I. Colombo, Maurizio Popoli, Francis S. Lee, Elena Tremoli, Silvia S. Barbieri
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 146, Iss , Pp 112557- (2022)
Depression is associated with thrombotic risk and arterial events, its proper management is strongly recommended in coronary artery disease (CAD) patients. We have previously shown that the Brain-Derived Neurotrophic Factor (BDNF)Val66Met polymorphis
Externí odkaz:
https://doaj.org/article/95242fcb1e95426c84c725334ffda223
Autor:
Vittorio Abbonante, Christian A. Di Buduo, Alessandro Malara, Pierre-Alexandre Laurent, Alessandra Balduini
Publikováno v:
Platelets, Vol 31, Iss 6, Pp 717-723 (2020)
Mechanisms related to platelet release in the context of the bone marrow niche are not completely known. In this review we discuss what has been discovered about four critical aspects of this process: 1) the bone marrow niche organization, 2) the rol
Externí odkaz:
https://doaj.org/article/c6e61ea15054473fbc5c3cd13c4a2b8d
Autor:
Loredana Bury, Alessandro Malara, Stefania Momi, Eleonora Petito, Alessandra Balduini, Paolo Gresele
Publikováno v:
Haematologica, Vol 104, Iss 7 (2019)
Platelet-type von Willebrand disease is an inherited platelet disorder characterized by thrombocytopenia with large platelets caused by gain-of-function variants in GP1BA leading to enhanced GPIbα-von Willebrand factor (vWF) interaction. GPIbα and
Externí odkaz:
https://doaj.org/article/3aa6f2a3286e4b06bc4a616a64ea19a2
Autor:
Alessandro Malara, Vittorio Abbonante, Maria Zingariello, Anna Rita Franco Migliaccio, Alessandra Balduini
Publikováno v:
Mediterranean Journal of Hematology and Infectious Diseases, Vol 10, Pp e2018068-e2018068 (2018)
In Primary Myelofibrosis (PMF), megakaryocyte dysplasia/hyperplasia determines the release of inflammatory cytokines that, in turn, stimulate stromal cells and induce bone marrow fibrosis. The pathogenic mechanism and the cells responsible for progre
Externí odkaz:
https://doaj.org/article/3291896293174b52b3977a2c6474cbb7
Autor:
Alessandro Malara, Cristian Gruppi, Giuseppe Celesti, Vittorio Abbonante, Gianluca Viarengo, Luigi Laghi, Luigi De Marco, Andrés F. Muro, Alessandra Balduini
Publikováno v:
Haematologica, Vol 103, Iss 2 (2018)
Externí odkaz:
https://doaj.org/article/37f251874612488199a3c554849ad8cf
Autor:
Alessandro Malara, Daniela Ligi, Christian A. Di Buduo, Ferdinando Mannello, Alessandra Balduini
Publikováno v:
Cells, Vol 7, Iss 7, p 80 (2018)
Metalloproteinases (MMPs) are zinc-dependent endopeptidases that play essential roles as the mediator of matrix degradation and remodeling during organogenesis, wound healing and angiogenesis. Although MMPs were originally identified as matrixin prot
Externí odkaz:
https://doaj.org/article/5d5fe9e000c64a0681b0be859c3b0690
Autor:
Alessandra Balduini, Christian Andrea Di Buduo, Alessandro Malara, Anna Lecchi, Paola Rebuzzini, Manuela Currao, Isabella Pallotta, Joseph A. Jakubowski, Marco Cattaneo
Publikováno v:
Haematologica, Vol 97, Iss 11 (2012)
Background The interaction of adenosine diphosphate with its P2Y1 and P2Y12 receptors on platelets is important for platelet function. However, nothing is known about adenosine diphosphate and its function in human megakaryocytes.Design and Methods W
Externí odkaz:
https://doaj.org/article/59d53b63d88a40829f93546db5a197b1
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e34449 (2012)
The interaction of megakaryocytes with matrix proteins of the osteoblastic and vascular niche is essential for megakaryocyte maturation and proplatelet formation. Fibrinogen is present in the vascular niche and the fibrinogen receptor α(IIb)β(3) is
Externí odkaz:
https://doaj.org/article/6c375a20bc6b4fb5a2ba059a05077e06