Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Alessandro Magrì"'
Autor:
Giuseppe Rospo, Annalisa Lorenzato, Nabil Amirouchene-Angelozzi, Alessandro Magrì, Carlotta Cancelliere, Giorgio Corti, Carola Negrino, Vito Amodio, Monica Montone, Alice Bartolini, Ludovic Barault, Luca Novara, Claudio Isella, Enzo Medico, Andrea Bertotti, Livio Trusolino, Giovanni Germano, Federica Di Nicolantonio, Alberto Bardelli
Publikováno v:
Genome Medicine, Vol 11, Iss 1, Pp 1-22 (2019)
Abstract Background Neoantigens that arise as a consequence of tumor-specific mutations can be recognized by T lymphocytes leading to effective immune surveillance. In colorectal cancer (CRC) and other tumor types, a high number of neoantigens is ass
Externí odkaz:
https://doaj.org/article/23b124a3611d4b43958fdd1407aa1693
Autor:
Alessandro Magrì, Monica Montone, Salvatore Siena, Luca Lazzari, Angela Bachi, Vittoria Matafora, Valentina Audrito, Annalisa Lorenzato, Pamela Arcella, Livio Trusolino, Silvia Deaglio, Federica Di Nicolantonio, Alberto Bardelli, Simona Lamba, Andrea Bertotti, Sabrina Arena
Publikováno v:
Cancers
Cancers, Vol 12, Iss 3, p 685 (2020)
Volume 12
Issue 3
Cancers, Vol 12, Iss 3, p 685 (2020)
Volume 12
Issue 3
The long-term efficacy of the Epidermal Growth Factor Receptor (EGFR)-targeted antibody cetuximab in advanced colorectal cancer (CRC) patients is limited by the emergence of drug-resistant (persister) cells. Recent studies in other cancer types have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64fe85ff1cbe633bc79926435c77c971
https://pubmed.ncbi.nlm.nih.gov/32183295
https://pubmed.ncbi.nlm.nih.gov/32183295
Autor:
Alberto Bardelli, Alessandro Magrì
Publikováno v:
Nature Reviews Gastroenterology & Hepatology. 16:651-653
During the metastatic process, cancer cells spread from the primary tumour to distant organs. Although metastases are the primary cause of cancer mortality, the dynamics of the metastatic process remain largely unknown. A new study suggests that duri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1eec41767084915b0e05b99fbf39cdcb
https://doi.org/10.1038/s41575-019-0200-4
https://doi.org/10.1038/s41575-019-0200-4
Autor:
Livio Trusolino, Federica Di Nicolantonio, Alberto Bardelli, Alice Bartolini, Enzo Medico, Alessandro Magrì, Ludovic Barault, Andrea Bertotti, Nabil Amirouchene-Angelozzi, Annalisa Lorenzato, Carola Negrino, Claudio Isella, Monica Montone, Vito Amodio, Giovanni Germano, Giorgio Corti, Giuseppe Rospo, Luca Novara, Carlotta Cancelliere
Publikováno v:
Genome Medicine
Genome Medicine, Vol 11, Iss 1, Pp 1-22 (2019)
Genome Medicine, Vol 11, Iss 1, Pp 1-22 (2019)
BackgroundNeoantigens that arise as a consequence of tumour-specific mutations can be recognized by T lymphocytes leading to effective immune surveillance. In colorectal cancer (CRC) and other tumour types, a high number of neoantigens is associated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::248e92ed2b4267cd3865350304cb5665
http://europepmc.org/articles/PMC6599263
http://europepmc.org/articles/PMC6599263
Autor:
Salvatore Siena, Alessandro Magrì, Giovanni Crisafulli, Vito Amodio, Cortt G. Piett, Luca Novara, Zachary D. Nagel, Ivana Sarotto, Federica Di Nicolantonio, Alessio Amatu, Nicole M. Reilly, Alberto Sogari, Alberto Bardelli, Simona Lamba, Andrea Sartore-Bianchi, Andrea Bertotti, Alice Bartolini, Livio Trusolino, Sabrina Arena, Mariangela Russo
Publikováno v:
Molecular Cancer Therapeutics. 18:A120-A120
Success in eradicating human cancer with targeted therapies is limited by the emergence of secondary resistance. The prevalent view is that resistance is a fait accompli: when treatment is initiated, tumors already contain drug-resistant mutant cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e87ee5af3601d61c0a98be569ba0acef
https://doi.org/10.1158/1535-7163.targ-19-a120
https://doi.org/10.1158/1535-7163.targ-19-a120
Autor:
Maurizio D'Incalci, Enrico Giraudo, Giovanni Crisafulli, Giovanni Randon, Andrea Satore-Bianchi, Nabil Amirouchene Angelozzi, Federica Di Nicolantonio, Alberto Bardelli, Simona Lamba, Alessandro Magrì, Salvatore Siena, Silvia Marsoni, Roberta Frappolli, Monica Montone, Giulia Lerda, Armando Orlandi, Ludovic Barault, Vito Amodio, Giuseppe Rospo, Alice Bartolini, Filippo de Braud, Filippo Pietrantonio, Benedetta Mussolin, Giulia Siravegna, Carlotta Cancelliere, Federica Maione, Giovanni Grmano
Publikováno v:
Cancer Immunology Research. 7:B069-B069
The tumor mutational burden affects immune surveillance and is associated with response to immune checkpoint blockade. We recently reported that inactivation of the DNA mismatch repair (MMR) pathway in cancer cells increases the mutational burden and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a849f946c1c7fc9ff022249741ca4c0b
https://doi.org/10.1158/2326-6074.cricimteatiaacr18-b069
https://doi.org/10.1158/2326-6074.cricimteatiaacr18-b069
Autor:
Federica Maione, Alessandro Magrì, F. de Braud, Andrea Sartore-Bianchi, Ludovic Barault, F. Di Nicolantonio, Maurizio D'Incalci, Alberto Bardelli, S. Marsoni, Giuseppe Rospo, Giovanni Germano, Mariangela Russo, Simona Lamba, F. Pietrantonio, S. Siena
Publikováno v:
Radiotherapy and Oncology. 133:S235-S236
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::541127a89179962b2bf7231c0f22bc71
https://doi.org/10.1016/s0167-8140(19)30873-4
https://doi.org/10.1016/s0167-8140(19)30873-4
Autor:
Giulia Lerda, Federica Morano, Salvatore Siena, Mariangela Russo, Alice Bartolini, Ludovic Barault, Federica Maione, Alessandro Magrì, Filippo Pietrantonio, Giovanni Germano, Enrico Giraudo, Monica Montone, Benedetta Mussolin, Maurizio D'Incalci, Silvia Marsoni, Federica Di Nicolantonio, Giulia Siravegna, Giovanni Crisafulli, Alberto Bardelli, Andrea Sartore-Bianchi, Armando Orlandi, Giuseppe Rospo, Filippo de Braud, Roberta Frapolli, Nabil Amirouchene-Angelozzi, Simona Lamba
Publikováno v:
Nature
Molecular alterations in genes involved in DNA mismatch repair (MMR) promote cancer initiation and foster tumour progression. Cancers deficient in MMR frequently show favourable prognosis and indolent progression. The functional basis of the clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe4ec99754fca8feafa8b5673b8795c6
http://hdl.handle.net/2318/1660203
http://hdl.handle.net/2318/1660203
Autor:
Ludovuc Barault, Giuseppe Rospo, Nabil Amirouchene Angelozzi, Enrico Giraudo, Monica Montone, Alessandro Magrì, Federica Maione, Mariangela Russo, Giovanni Germano, Simona Lamba, Federica Di Nicolantonio, Alberto Bardelli
Publikováno v:
Cancer Immunology Research. 5:PR13-PR13
Colorectal, ovarian, endometrial and other tumors carrying defects in DNA mismatch repair often show favorable prognosis and indolent progression. The genomes of these tumors -also known as microsatellite unstable (MSI) cancers- bear hundreds of thou
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3288880ea953d71846de071b724254e6
https://doi.org/10.1158/2326-6074.tumimm16-pr13
https://doi.org/10.1158/2326-6074.tumimm16-pr13
Autor:
Salvatore Siena, Filippo de Braud, Enrico Giraudo, Mariangela Russo, Federica Maione, Benedetta Mussolin, Ludovic Barault, Giulia Siravegna, Nabil Amirouchene-Angelozzi, Giovanni Germano, Andrea Sartore-Bianchi, Roberta Frapolli, Alice Bartolini, Federica Morano, Monica Montone, Armando Orlandi, Maurizio D'Incalci, Giuseppe Rospo, Giulia Lerda, Alberto Bardelli, Giovanni Crisafulli, Alessandro Magrì, Silvia Marsoni, Simona Lamba, Federica DiNicolantonio, Filippo Pietrantonio
Publikováno v:
Cancer Research. 78:5723-5723
Colorectal, ovarian, endometrial and other tumors carrying defects in DNA mismatch repair often show favorable prognosis and indolent progression. The genomes of these tumors bear hundreds of thousands of somatic mutations, a feature which fosters ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::03234062bb8dd23dae95bd2ce9d198a0
https://doi.org/10.1158/1538-7445.am2018-5723
https://doi.org/10.1158/1538-7445.am2018-5723