Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Alessandro G, Salerno"'
Autor:
Coen van Solingen, Scott R. Oldebeken, Alessandro G. Salerno, Amarylis C. B. A. Wanschel, Kathryn J. Moore
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 8 (2021)
Investigations into the regulatory mechanisms controlling cholesterol homeostasis have proven fruitful in identifying low-density lipoprotein (LDL)-lowering therapies to reduce the risk of atherosclerotic cardiovascular disease. A major advance was t
Externí odkaz:
https://doaj.org/article/d7a3d43ee4e840f0bee2edb841757972
Autor:
Jose Manuel Condor Capcha, Guerline Lambert, Derek M. Dykxhoorn, Alessandro G. Salerno, Joshua M. Hare, Michael A. Whitt, Savita Pahwa, Dushyantha T. Jayaweera, Lina A. Shehadeh
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2021)
The COVID-19 pandemic caused by the SARS-CoV-2 coronavirus requires reliable assays for studying viral entry mechanisms which remains poorly understood. This knowledge is important for the development of therapeutic approaches to control SARS-CoV-2 i
Externí odkaz:
https://doaj.org/article/1f2f57c7537c4768944f2e70a6238ceb
Autor:
Alessandro G. Salerno, Coen van Solingen, Elena Scotti, Amarylis C. B. A. Wanschel, Milessa S. Afonso, Scott R. Oldebeken, Westley Spiro, Peter Tontonoz, Katey J. Rayner, Kathryn J. Moore
Publikováno v:
Frontiers in Cardiovascular Medicine, Vol 7 (2020)
MicroRNAs (miRNA) have emerged as important post-transcriptional regulators of metabolic pathways that contribute to cellular and systemic lipoprotein homeostasis. Here, we identify two conserved miRNAs, miR-224, and miR-520d, which target gene netwo
Externí odkaz:
https://doaj.org/article/dd888e03050d4c62a7d61d2593abde3f
Autor:
Raul A Dulce, Rosemeire M Kanashiro-Takeuchi, Lauro M Takeuchi, Alessandro G Salerno, Amarylis C B A Wanschel, Shathiyah Kulandavelu, Wayne Balkan, Marilia S S R Zuttion, Renzhi Cai, Andrew V Schally, Joshua M Hare
Publikováno v:
Cardiovascular Research. 118:3586-3601
Aims To test the hypothesis that the activation of the growth hormone-releasing hormone (GHRH) receptor signalling pathway within the myocardium both prevents and reverses diastolic dysfunction and pathophysiologic features consistent with heart fail
Autor:
Amarylis C. B. A. Wanschel, Daniele M. Guizoni, Estela Lorza-Gil, Alessandro G. Salerno, Adriene A. Paiva, Gabriel G. Dorighello, Ana Paula Davel, Wayne Balkan, Joshua M. Hare, Helena C. F. Oliveira
Publikováno v:
Biomolecules, Vol 11, Iss 1, p 69 (2021)
Endothelial dysfunction precedes atherosclerosis and is an independent predictor of cardiovascular events. Cholesterol levels and oxidative stress are key contributors to endothelial damage, whereas high levels of plasma high-density lipoproteins (HD
Externí odkaz:
https://doaj.org/article/6e5b59f4fb194832873252fbe9e0250e
Publikováno v:
Expert Opin Biol Ther
INTRODUCTION: Mesenchymal stromal cells (MSCs; AKA mesenchymal stem cells) stimulate healing and reduce inflammation. Promising therapeutic responses are seen in many late-phase clinical trials, but others have not satisfied their primary endpoints,
Autor:
Amarylis Wanschel, Angeliki Daiou, Jeffin Kuznetsoff, Stefan Kurtenbach, Katerina Petalidou, Thomai Mouskeftara, Helen G. Gika, Daniel A. Rodriguez, Eleftherios I. Papadopoulos, Georgios Siokatas, Polyxeni P. Sarri, Kyriaki Karava, Efthimios Tsivoglou, Christine Kottaridi, Alessandro G. Salerno, Krystalenia Valasaki, Wayne Balkan, Derek Dykxhoorn, Andrew Schally, Dimitrios L. Kontoyiannis, Antigone Lazou, Konstantinos E. Hatzistergos, Joshua Hare
Here, we present an O2-independent/HIF-1α (Hypoxia inducible factor-1α)-dependent mechanism that regulates developmental and regenerative growth of mammalian cardiomyoblasts. An autocrine feedback mechanism of GH/IGF1/SST (Growth hormone/Insulin-li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4152859a3a9d96014a2863c92f053285
https://doi.org/10.1101/2022.01.31.478572
https://doi.org/10.1101/2022.01.31.478572
Autor:
Raul A, Dulce, Rosemeire M, Kanashiro-Takeuchi, Lauro M, Takeuchi, Alessandro G, Salerno, Amarylis C B A, Wanschel, Shathiyah, Kulandavelu, Wayne, Balkan, Marilia S S R, Zuttion, Renzhi, Cai, Andrew V, Schally, Joshua M, Hare
Publikováno v:
Cardiovasc Res
To test the hypothesis that the activation of the growth hormone-releasing hormone (GHRH) receptor signaling pathway within the myocardium both prevents and reverses diastolic dysfunction and pathophysiologic features consistent with heart failure wi
Autor:
José Roberto Trigo, Jane Cristina de Souza, Ana Carolina Marques, Estela Lorza-Gil, Jean Franciesco Vettorazzi, Marta García-Arévalo, Helena C. F. Oliveira, Alessandro G. Salerno
Publikováno v:
Journal of Cellular Physiology. 234:11047-11059
New onset of diabetes is associated with the use of statins. We have recently demonstrated that pravastatin-treated hypercholesterolemic LDL receptor knockout (LDLr-/- ) mice exhibit reductions in insulin secretion and increased islet cell death and
Autor:
Rodrigo H M M Granja, Alessandro G. Salerno, Amarylis C. B. A. Wanschel, Alfredo M. Montes Niño
Publikováno v:
Food Control. 72:289-292
β-adrenergic agonist ractopamine is increasingly used in the swine industry due to consumer demand for leaner pork products. Ractopamine redirects nutrients to favor leanness rather than fat deposition, improves growth and carcass traits of finishin