Zobrazeno 1 - 10
of 477
pro vyhledávání: '"Alessandro D. Santin"'
Autor:
Dana M. Roque, Eric R. Siegel, Natalia Buza, Stefania Bellone, Gloria S. Huang, Gary Altwerger, Vaagn Andikyan, Mitchell Clark, Masoud Azodi, Peter E. Schwartz, Gautam G. Rao, Elena Ratner, Alessandro D. Santin
Publikováno v:
BJC Reports, Vol 2, Iss 1, Pp 1-7 (2024)
Abstract Background Ixabepilone may retain activity in paclitaxel-resistant disease. We previously reported improved response rates (ORR), progression-free (PFS), and overall survival (OS) conferred by ixabepilone+bevacizumab (IXA + BEV) compared to
Externí odkaz:
https://doaj.org/article/f49671ab396045a1849b78083c690bd0
Autor:
Tobias Max Philipp Hartwich, Miranda Mansolf, Cem Demirkiran, Michelle Greenman, Stefania Bellone, Blair McNamara, Shuvro P. Nandi, Ludmil B. Alexandrov, Yang Yang‐Hartwich, Silvia Coma, Jonathan Pachter, Alessandro D. Santin
Publikováno v:
Cancer Medicine, Vol 13, Iss 17, Pp n/a-n/a (2024)
Abstract Background High‐grade endometrial cancers (EAC) are aggressive tumors with a high risk of progression after treatment. As EAC may harbor mutations in the RAS/MAPK pathways, we evaluated the preclinical in vitro and in vivo efficacy of avut
Externí odkaz:
https://doaj.org/article/c903116f7e7848cf816112aa15bc9253
Autor:
Michelle Greenman, Stefania Bellone, Cem Demirkiran, Tobias Max Philipp Hartwich, Alessandro D. Santin
Publikováno v:
Gynecologic Oncology Reports, Vol 54, Iss , Pp 101459- (2024)
Background: Treatment of recurrent platinum-resistant high grade serous ovarian cancer (HGSOC) remains a challenge. Novel treatment options for recurrent disease are an unmet need. Case: A 69-year-old with recurrent, metastatic, platinum-resistant HG
Externí odkaz:
https://doaj.org/article/05c903bfcc1a4000b08786ea06630865
Publikováno v:
Gynecologic Oncology Reports, Vol 51, Iss , Pp 101324- (2024)
Up to 30 % of COVID-infected patients may develop post-acute sequelae of COVID-19 (PASC), also known as Long COVID (LC), a syndrome characterized by a variety of debilitating symptoms lasting for more than 3 months after the acute infection. While th
Externí odkaz:
https://doaj.org/article/b9c2e6db927c46d0abad4bbc55e50e26
Publikováno v:
Gynecologic Oncology Reports, Vol 50, Iss , Pp 101301- (2023)
Post-acute sequelae of COVID-19 (PASC), also known as Long-Covid (LC), may affect 10–30 % of COVID-infected patients, and is characterized by a variety of debilitating symptoms lasting over 3 months after the acute infection, including but not limi
Externí odkaz:
https://doaj.org/article/1f5b58ce2ece47c78b1217bacc38bd76
Autor:
Blair McNamara, Stefania Bellone, Cem Demirkiran, Tobias Max Philipp Hartwich, Alessandro D. Santin
Publikováno v:
Gynecologic Oncology Reports, Vol 48, Iss , Pp 101219- (2023)
Background: Treatment of uterine serous carcinoma (USC) is challenging; effective treatment options for metastatic and recurrent disease are needed. Case: A 68-year-old woman with recurrent, metastatic, USC overexpressing HER2/neu experienced durable
Externí odkaz:
https://doaj.org/article/65f35d1815de4ce1953b17e0506522e9
Autor:
Blair McNamara, Stefania Bellone, Cem Demirkiran, Tobias Max Philipp Hartwich, Alessandro D. Santin
Publikováno v:
Gynecologic Oncology Reports, Vol 48, Iss , Pp 101218- (2023)
Background: Treatment of ovarian clear cell carcinoma (CCC) poses many challenges. Effective treatment options for recurrent and metastatic disease remain limited. Case: A 70-year-old woman with recurrent metastatic ovarian CCC experienced durable re
Externí odkaz:
https://doaj.org/article/d7d8924ecf584037b3530fc91d3acc9d
Publikováno v:
BioMedInformatics, Vol 2, Iss 4, Pp 553-564 (2022)
Omicron is the dominant strain of COVID-19 in the United States and worldwide. Although this variant is highly transmissible and may evade natural immunity, vaccines, and therapeutic antibodies, preclinical results in animal models and clinical data
Externí odkaz:
https://doaj.org/article/6224b96a11304c988037fbf9b4310f82
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 17039 (2023)
Consistent with well-established biochemical properties of coronaviruses, sialylated glycan attachments between SARS-CoV-2 spike protein (SP) and host cells are key to the virus’s pathology. SARS-CoV-2 SP attaches to and aggregates red blood cells
Externí odkaz:
https://doaj.org/article/95b1145981b141de86f5de3334c0381b
Publikováno v:
Molecules, Vol 28, Iss 21, p 7389 (2023)
Antibody–drug conjugates (ADCs) are a new class of targeted anti-cancer therapies that combine a monoclonal tumor-surface-receptor-targeting antibody with a highly cytotoxic molecule payload bonded through specifically designed cleavable or non-cle
Externí odkaz:
https://doaj.org/article/d5e1b3ba510d43a9a6f28f0100da959b