Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Alessandro Balbi"'
Autor:
Alessandro Balbi, Chiara Macciò, Maria Anzaldi, Valentina Oliveri, Maurizio Viale, Patrizio Castagnola, Camillo Rosano
By a scaffold shortening strategy, a small series of retinoidal amides fenretinide (4-HPR) analogs have been synthesized from α, β-ionones and tested for their antiproliferative and differentiating activities, and antioxidant effect. The antiprolif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598cb7e5378e684b935dd157aafce610
http://hdl.handle.net/20.500.11769/372512
http://hdl.handle.net/20.500.11769/372512
Autor:
Maria Bertolotto, Franco Dallegri, Luciano Ottonello, Mauro Mazzei, Maria Anzaldi, Chiara Macciò, Alessandro Balbi
Publikováno v:
Chemistry & Biodiversity. 6:1674-1687
A series of N-substituted pyrazole derivatives have been synthesized and tested for their anticancer effect on the HL-60 leukaemia cell line. Four were active both in cell-growth inhibition and in inducing apoptosis. The inhibition of cell growth mai
Autor:
Paolo La Colla, M. Mazzei, Fabio Marongiu, Maurizio Fermeglia, Erika Nieddu, Marco Ferrone, Mauro Mazzei, Mariangela Miele, Cristina Ibba, Alessandro Balbi, Sabrina Pricl, Roberta Loddo
Publikováno v:
Bioorganic & Medicinal Chemistry. 16:2591-2605
Some Mannich bases of 7-hydroxycoumarin (2) and their simple derivatives (3 and 4) were prepared and tested against viruses containing single-stranded, positive-sense RNA genomes (ssRNA(+)). This study was directed toward Flaviviridae and, in particu
Publikováno v:
Helvetica Chimica Acta. 85:1698-1705
3-[(3-Aminopropyl)amino]-1-oxo-1H-naphtho[2,1-b]pyran-2-carbaldehyde (10) was synthesized by nucleophilic substitution reaction of 2-(3-dimethylamino)-1-oxo-1H-naphtho[2,1-b]pyran-2-carbaldehyde (9) and the monoprotected propane-1,3-diamine. The reac
Autor:
Alessandro Balbi, Georgy A. Nevinsky, Laura Tarrago-Litvak, Mauro Mazzei, Marie Line Andreola, Igor V. Martyanov, Simon Litvak, Enzo Sottofattori, Olga D. Zakharova, Ekaterina Y. Yurchenko, Dmitry V. Pyshnyi, Paola Babbi
Publikováno v:
Antisense and Nucleic Acid Drug Development. 9:473-480
Ten different pyranone-related substituents (chromones or coumarins) were covalently linked to the 5' end of various oligonucleotides (ODN). The interaction of these compounds with human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT
Publikováno v:
Journal of Heterocyclic Chemistry. 35:1377-1380
Reaction of α- and β-ionones 1 and 2 with dialkylformamide/phosphorus oxychloride affords enamines 6 and 7 along with the expected chloro derivatives 4 and 5. Reaction of 6a with hydrazines, hydroxylamine and guanidine furnished pyrazoles, isoxazol
Publikováno v:
Journal of Pharmaceutical and Biomedical Analysis. 18:213-217
A high-performance liquid chromatographic method for the simultaneous determination of magnesium ascorbyl phosphate (I), imidazolidinylurea (II), a mixture of methyl-(III), ethyl-(IV), propyl-(V), butyl-(VI) parabens dissolved in phenoxyethanol, and
Autor:
Olga D. Zakharova, Enzo Sottofattori, G. A. Maksakova, Georgy A. Nevinsky, Mauro Mazzei, Simon Litvak, Igor V. Martyanov, Laura Tarrago-Litvak, Dmitry V. Pyshnyi, Alessandro Balbi
Publikováno v:
IUBMB Life. 45:857-864
We have carried out a comparison of KM and Vmax values for various primers in the polymerization reaction catalyzed by the HIV-1 RT. The affinity of RT for complementary d(pT)6 containing two different 5′-end pyranone derivatives was 2–3 orders o
Publikováno v:
Journal of Heterocyclic Chemistry. 33:347-350
The title compounds were prepared starting from the synthones 6 using two different synthetic approaches: 3-substituted 1,4-benzothiazine 1,1-dioxides were synthesised by cyclisation with phosphorus oxychloride as the Vilsmeier reagent, while 4,1,2-b
Autor:
Maria Anzaldi, Laura Emionite, Cinzia Aiello, Alessandro Balbi, Federica Albicini, Carla Fenoglio, Rosaria Gangemi, Maurizio Viale
Publikováno v:
Pharmacological reports : PR. 65(3)
Background In previous papers we demonstrated that the activity of short heteroretinoids as anti-proliferative and pro-apoptotic compounds was deeply linked to their heterocyclic moiety and that ionone-derived 1,5-pyrazoles had the highest anti-proli