Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Alessandro Ascione"'
Autor:
Alessandro Ascione, Marcello Belfiore, Jaana Vesterinen, Mihaela Buda, Wolf Holtkamp, Francesca Luciani
Publikováno v:
mAbs, Vol 16, Iss 1 (2024)
ABSTRACTTherapeutic mAbs show a specific “charge fingerprint” that may affect safety and efficacy, and, as such, it is often identified as a critical quality attribute (CQA). Capillary iso-electric focusing (cIEF), commonly used for the evaluatio
Externí odkaz:
https://doaj.org/article/90b4b78ca43542ea9001ea85f6de584f
Autor:
Alessandro Ascione, Claudia Arenaccio, Alessandra Mallano, Michela Flego, Mara Gellini, Mauro Andreotti, Craig Fenwick, Giuseppe Pantaleo, Stefano Vella, Maurizio Federico
Publikováno v:
BMC Biotechnology, Vol 19, Iss 1, Pp 1-15 (2019)
Abstract Background Lymphocyte-activation gene (LAG)3 is a 498 aa transmembrane type I protein acting as an immune inhibitory receptor. It is expressed on activated lymphocytes, natural killer cells and plasmacytoid dendritic cells. In activated lymp
Externí odkaz:
https://doaj.org/article/ea888644d8434b0da4411f120e225ee5
Autor:
Michela Flego, Aldo Frau, Luisa Accardi, Alessandra Mallano, Alessandro Ascione, Mara Gellini, Elisa Fanunza, Stefano Vella, Paola Di Bonito, Enzo Tramontano
Publikováno v:
BMC Biotechnology, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Ebola hemorrhagic fever is caused by the Ebola filovirus (EBOV), which is one of the most aggressive infectious agents known worldwide. The EBOV pathogenesis starts with uncontrolled viral replication and subversion of both the in
Externí odkaz:
https://doaj.org/article/39ea074b00a5421d9e6198af479a0d48
Publikováno v:
International Reviews of Immunology
article-version (VoR) Version of Record
article-version (VoR) Version of Record
Many recent studies have reported the onset of a robust antibody response to SARS-CoV-2 infection and highlighted produced antibodies’ specific qualitative and quantitative aspects, relevant for developing antibody-based diagnostic and therapeutic
Autor:
Maurizio Federico, Flavia Ferrantelli, Patrizia Leone, Claudia Arenaccio, Alessandro Ascione, Michela Flego, Zulema A. Percario, Luisa Accardi, Francesco Manfredi, Chiara Chiozzini, Paola Di Bonito, Eleonora Olivetta
Publikováno v:
International Journal of Nanomedicine. 14:8755-8768
Purpose Single-chain variable fragments (scFvs) are one of the smallest antigen-binding units having the invaluable advantage to be expressed by a unique short open reading frame (ORF). Despite their reduced size, spontaneous cell entry of scFvs rema
Autor:
Maria Luisa Dupuis, Alessandra Boe, Mauro Andreotti, Carla Raggi, Mara Gellini, Alessandra Mallano, Alessandro Ascione, Eleonora Petrucci, Gianni Colotti, Stefano Barca, Stefano Vella, Roberta Riccioni, Michela Flego
Publikováno v:
Human antibodies 29 (2021): 63–84. doi:10.3233/HAB-200431
info:cnr-pdr/source/autori:Flego M.; Colotti G.; Ascione A.; Dupuis M.L.; Petrucci E.; Riccioni R.; Andreotti M.; Raggi C.; Boe A.; Barca S.; Gellini M.; Vella S.; Mallano A./titolo:Isolation and preliminary characterization of a human 'phage display'-derived antibody against neural adhesion molecule-1 antigen interfering with fibroblast growth factor receptor-1 binding/doi:10.3233%2FHAB-200431/rivista:Human antibodies/anno:2021/pagina_da:63/pagina_a:84/intervallo_pagine:63–84/volume:29
info:cnr-pdr/source/autori:Flego M.; Colotti G.; Ascione A.; Dupuis M.L.; Petrucci E.; Riccioni R.; Andreotti M.; Raggi C.; Boe A.; Barca S.; Gellini M.; Vella S.; Mallano A./titolo:Isolation and preliminary characterization of a human 'phage display'-derived antibody against neural adhesion molecule-1 antigen interfering with fibroblast growth factor receptor-1 binding/doi:10.3233%2FHAB-200431/rivista:Human antibodies/anno:2021/pagina_da:63/pagina_a:84/intervallo_pagine:63–84/volume:29
BACKGROUND: The NCAM or CD56 antigen is a cell surface glycoprotein belonging to the immunoglobulin super-family involved in cell-cell and cell-matrix adhesion. NCAM is also over-expressed in many tumour types and is considered a tumour associated an
Autor:
Aldo Frau, Alessandra Mallano, Paola Di Bonito, Luisa Accardi, Enzo Tramontano, Elisa Fanunza, Alessandro Ascione, Michela Flego, Mara Gellini, Stefano Vella
Publikováno v:
BMC Biotechnology
BMC Biotechnology, Vol 19, Iss 1, Pp 1-12 (2019)
BMC Biotechnology, Vol 19, Iss 1, Pp 1-12 (2019)
Background Ebola hemorrhagic fever is caused by the Ebola filovirus (EBOV), which is one of the most aggressive infectious agents known worldwide. The EBOV pathogenesis starts with uncontrolled viral replication and subversion of both the innate and
Autor:
Flavia, Ferrantelli, Claudia, Arenaccio, Francesco, Manfredi, Eleonora, Olivetta, Chiara, Chiozzini, Patrizia, Leone, Zulema, Percario, Alessandro, Ascione, Michela, Flego, Paola, Di Bonito, Luisa, Accardi, Maurizio, Federico
Publikováno v:
International Journal of Nanomedicine
Purpose Single-chain variable fragments (scFvs) are one of the smallest antigen-binding units having the invaluable advantage to be expressed by a unique short open reading frame (ORF). Despite their reduced size, spontaneous cell entry of scFvs rema
Autor:
Claudia Arenaccio, Mauro Andreotti, Alessandra Mallano, Craig Fenwick, Michela Flego, Maurizio Federico, Stefano Vella, Alessandro Ascione, Giuseppe Pantaleo, Mara Gellini
Publikováno v:
BMC Biotechnology, Vol 19, Iss 1, Pp 1-15 (2019)
Background Lymphocyte-activation gene (LAG)3 is a 498 aa transmembrane type I protein acting as an immune inhibitory receptor. It is expressed on activated lymphocytes, natural killer cells and plasmacytoid dendritic cells. In activated lymphocytes,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b31ae43397e4b088be5d7b70e109421
https://hdl.handle.net/11590/374098
https://hdl.handle.net/11590/374098
Autor:
Alessandro Ascione, Valentina Fiori, Mara Gellini, Silvia Zamboni, Alessandra Mallano, Sabrina Dominici, Mauro Magnani, Maria Luisa Dupuis, Michela Flego, Maurizio Cianfriglia
Publikováno v:
The Open Pharmacology Journal. 6:1-11
Carcinoembryonic antigen–related cell adhesion molecule 1 (CEACAM1) is a cell surface glycoprotein involved in intercellular binding, belonging to the immunoglobulin superfamily. It is involved in cell-cell recognition and modulates cellular proces