Zobrazeno 1 - 10
of 121
pro vyhledávání: '"Alessandro Arcovito"'
Autor:
Noah Giacon, Ettore Lo Cascio, Valeria Pennacchietti, Flavio De Maio, Giulia Santarelli, Diego Sibilia, Federica Tiberio, Maurizio Sanguinetti, Wanda Lattanzi, Angelo Toto, Alessandro Arcovito
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The COVID-19 pandemic caused by SARS-CoV-2 has highlighted the urgent need for innovative antiviral strategies to fight viral infections. Although a substantial part of the overall effort has been directed at the Spike protein to create an e
Externí odkaz:
https://doaj.org/article/1ddadc7741ce42c7a61846415285a350
Autor:
Francesco Marrocco, Elisabetta Falvo, Luciana Mosca, Giada Tisci, Alessandro Arcovito, Alice Reccagni, Cristina Limatola, Roberta Bernardini, Pierpaolo Ceci, Giuseppina D’Alessandro, Gianni Colotti
Publikováno v:
Cell Death and Disease, Vol 15, Iss 4, Pp 1-10 (2024)
Abstract Gliomas are among the most fatal tumors, and the available therapeutic options are very limited. Additionally, the blood-brain barrier (BBB) prevents most drugs from entering the brain. We designed and produced a ferritin-based stimuli-sensi
Externí odkaz:
https://doaj.org/article/6e3bf7316b2d4140a4a9dc60640a5167
Autor:
Noah Giacon, Ettore Lo Cascio, Darcy S. Davidson, Marcelo D. Polêto, Justin A. Lemkul, Valeria Pennacchietti, Livia Pagano, Carlotta Zamparelli, Angelo Toto, Alessandro Arcovito
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 3259-3271 (2023)
The Envelope (E) protein of SARS-CoV-2 plays a key role in virus maturation, assembly, and virulence mechanisms. The E protein is characterized by the presence of a PDZ-binding motif (PBM) at its C-terminus that allows it to interact with several PDZ
Externí odkaz:
https://doaj.org/article/5f87ea47f88e4bfda42747021ccdc226
Autor:
Giuseppina Nocca, Alessandro Arcovito, Nermeen A. Elkasabgy, Mona Basha, Noah Giacon, Elena Mazzinelli, Mohammed S. Abdel-Maksoud, Rabab Kamel
Publikováno v:
Pharmaceutics, Vol 15, Iss 12, p 2738 (2023)
Cellulose, the most abundant biopolymer in nature, is derived from various sources. The production of pharmaceutical textiles based on cellulose represents a growing sector. In medicated textiles, textile and pharmaceutical sciences are integrated to
Externí odkaz:
https://doaj.org/article/cacbfd720bd049298ff3390bab1d91e8
Autor:
Thanalai Poonsiri, Davide Dell’Accantera, Valentina Loconte, Alessandro Casnati, Laura Cervoni, Alessandro Arcovito, Stefano Benini, Alberto Ferrari, Marco Cipolloni, Elisa Cacioni, Francesca De Franco, Nicola Giacchè, Serena Rinaldo, Claudia Folli, Francesco Sansone, Rodolfo Berni, Michele Cianci
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 1, p 479 (2023)
Transthyretin (TTR) is an amyloidogenic homotetramer involved in the transport of thyroxine in blood and cerebrospinal fluid. To date, more than 130 TTR point mutations are known to destabilise the TTR tetramer, leading to its extracellular pathologi
Externí odkaz:
https://doaj.org/article/656d5dbbb7e544f2a6912ca4c7534197
Autor:
Serena Brundu, Virginia Napolitano, Giulia Franzolin, Ettore Lo Cascio, Roberta Mastrantonio, Gabriele Sardo, Eliano Cascardi, Federica Verginelli, Sergio Sarnataro, Gennaro Gambardella, Alberto Pisacane, Alessandro Arcovito, Carla Boccaccio, Paolo M Comoglio, Enrico Giraudo, Luca Tamagnone
Publikováno v:
EMBO Molecular Medicine, Vol 15, Iss 3, Pp n/a-n/a (2023)
Abstract The genetic changes sustaining the development of cancers of unknown primary (CUP) remain elusive. The whole‐exome genomic profiling of 14 rigorously selected CUP samples did not reveal specific recurring mutation in known driver genes. Ho
Externí odkaz:
https://doaj.org/article/987698c7f10d4c4294c18aba6c9e4084
Autor:
Lorena Di Pietro, Marta Barba, Daniela Palacios, Federica Tiberio, Chiara Prampolini, Mirko Baranzini, Ornella Parolini, Alessandro Arcovito, Wanda Lattanzi
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Abstract RUNX2 encodes the master bone transcription factor driving skeletal development in vertebrates, and playing a specific role in craniofacial and skull morphogenesis. The anatomically modern human (AMH) features sequence changes in the RUNX2 l
Externí odkaz:
https://doaj.org/article/0bf8edca908b4d4fb42a7584593ca882
Autor:
Silvia Rizzo, Maura Di Vito, Elena Mazzinelli, Ilaria Favuzzi, Riccardo Torelli, Margherita Cacaci, Alessandro Arcovito, Maurizio Sanguinetti, Stefania Garzoli, Giuseppina Nocca, Francesca Bugli
Publikováno v:
Plants, Vol 12, Iss 13, p 2437 (2023)
Researchers have explored natural products to combat the antibiotic resistance of various microorganisms. Cinnamaldehyde (CIN), a major component of cinnamon essential oil (CC-EO), has been found to effectively inhibit the growth of bacteria, fungi,
Externí odkaz:
https://doaj.org/article/f7e318263671413495c746da7c56afc1
Autor:
Elena Mazzinelli, Ilaria Favuzzi, Alessandro Arcovito, Raffaella Castagnola, Giorgia Fratocchi, Alvaro Mordente, Giuseppina Nocca
Publikováno v:
Pharmaceutics, Vol 15, Iss 5, p 1559 (2023)
Due to its numerous advantages, such as excellent drug accessibility, rapid absorption, and bypass of first-pass metabolism, the route of drug administration that involves crossing the oral mucosa is highly favored. As a result, there is significant
Externí odkaz:
https://doaj.org/article/69b1af62a4e2403fad6d369e903eab33
Autor:
Ettore Lo Cascio, Angelo Toto, Gabriele Babini, Flavio De Maio, Maurizio Sanguinetti, Alvaro Mordente, Stefano Della Longa, Alessandro Arcovito
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 19, Iss , Pp 1838-1847 (2021)
Short Linear Motifs (SLiMs) are functional protein microdomains that typically mediate interactions between a short linear region in one protein and a globular domain in another. Surface Plasmon Resonance assays have been performed to determine the b
Externí odkaz:
https://doaj.org/article/bf96ef5a1f9242f290b6fa6905ec77aa