Zobrazeno 1 - 10
of 232
pro vyhledávání: '"Alessandro Vatrella"'
Autor:
Antonio Maiorano, Chiara Lupia, Nicola Montenegro, Giuseppe Neri, Andrea Bruni, Eugenio Garofalo, Federico Longhini, Claudia Crimi, Angelantonio Maglio, Alessandro Vatrella, Girolamo Pelaia, Corrado Pelaia
Publikováno v:
Frontiers in Medicine, Vol 11 (2024)
Beclomethasone dipropionate/formoterol fumarate/glycopyrronium (BDP/FF/G) single inhaler extrafine triple therapy is effective for the treatment of uncontrolled asthma. Nevertheless, there is a lack of data about the use of diaphragmatic ultrasonogra
Externí odkaz:
https://doaj.org/article/8e762ecf86df498889073411eb51e0f6
Autor:
Giovanna Elisiana Carpagnano, Andrea Portacci, Santi Nolasco, Aikaterini Detoraki, Alessandro Vatrella, Cecilia Calabrese, Corrado Pelaia, Francesca Montagnolo, Giulia Scioscia, Giuseppe Valenti, Maria D’Amato, Maria Filomena Caiaffa, Massimo Triggiani, Nicola Scichilone, Claudia Crimi
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionClinical remission (CliR) achievement has been recognized as a new potential outcome in severe asthma. Nevertheless, we still lack a detailed profile of what features could better identify patients undergoing clinical remission. In this s
Externí odkaz:
https://doaj.org/article/0c7c9e26d5744c2e93df0d4eb67ad39d
Autor:
Ilaria Salvato, Luca Ricciardi, Jessica Dal Col, Annunziata Nigro, Giorgio Giurato, Domenico Memoli, Assunta Sellitto, Erwin Pavel Lamparelli, Maria Assunta Crescenzi, Monica Vitale, Alessandro Vatrella, Francesco Nucera, Paola Brun, Federico Caicci, Paola Dama, Thomas Stiff, Leandro Castellano, Sobia Idrees, Matt D. Johansen, Alen Faiz, Peter A. Wark, Philip M. Hansbro, Ian M. Adcock, Gaetano Caramori, Cristiana Stellato
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionThe RNA-binding protein AU-rich-element factor-1 (AUF-1) participates to posttranscriptional regulation of genes involved in inflammation and cellular senescence, two pathogenic mechanisms of chronic obstructive pulmonary disease (COPD).
Externí odkaz:
https://doaj.org/article/fe7d7b5136784084a80901875472e5fb
Autor:
Corrado Pelaia, Alida Benfante, Maria Teresa Busceti, Maria Filomena Caiaffa, Raffaele Campisi, Giovanna Elisiana Carpagnano, Nunzio Crimi, Maria D’Amato, Maria Pia Foschino Barbaro, Angelantonio Maglio, Elena Minenna, Santi Nolasco, Giuseppe Paglino, Francesco Papia, Girolamo Pelaia, Andrea Portacci, Luisa Ricciardi, Nicola Scichilone, Giulia Scioscia, Massimo Triggiani, Giuseppe Valenti, Alessandro Vatrella, Claudia Crimi
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundThe efficacy of dupilumab as biological treatment of severe asthma and chronic rhinosinusitis with nasal polyps (CRSwNP) depends on its ability to inhibit the pathophysiologic mechanisms involved in type 2 inflammation.ObjectiveTo assess in
Externí odkaz:
https://doaj.org/article/6af27269a4a84e099db8d6152853d722
Autor:
Corrado Pelaia, Giada Procopio, Fioramante Lello Rotundo, Maria Rosaria Deodato, Anna Ferrante Bannera, Francesco Giuseppe Tropea, Anna Cancelliere, Alessandro Vatrella, Girolamo Pelaia
Publikováno v:
Therapeutic Advances in Respiratory Disease, Vol 17 (2023)
Background: The small airway disease has been recognized as a central feature of chronic obstructive pulmonary disease (COPD). Triple fixed combination beclomethasone dipropionate/formoterol fumarate/glycopyrronium (BDP/FF/G) is provided as a pressur
Externí odkaz:
https://doaj.org/article/01199e0e1e584d8ba2173121f825e2e5
Autor:
Chiara Colarusso, Michela Terlizzi, Angelantonio Maglio, Antonio Molino, Claudio Candia, Carolina Vitale, Philip M. Hansbro, Alessandro Vatrella, Aldo Pinto, Rosalinda Sorrentino
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
Severe acute respiratory syndrome-coronavirus-2 (SARS‐CoV‐2), responsible for COVID-19, has caused a global pandemic. Observational studies revealed a condition, herein called as Long-COVID syndrome (PC), that affects both moderately and severely
Externí odkaz:
https://doaj.org/article/146083c0b6a04f19926bce4c3b522575
Autor:
Corrado Pelaia, Enrico Heffler, Claudia Crimi, Angelantonio Maglio, Alessandro Vatrella, Girolamo Pelaia, Giorgio Walter Canonica
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Interleukins (IL)-4 and -13 play a pivotal role in the pathobiology of type-2 asthma. Indeed, IL-4 is crucially involved in Th2 cell differentiation, immunoglobulin (Ig) class switching and eosinophil trafficking. IL-13 cooperates with IL-4 in promot
Externí odkaz:
https://doaj.org/article/0f19d040f9af4eecb7bed80c4f58e136
Autor:
Angelantonio Maglio, Carolina Vitale, Corrado Pelaia, Maria D’Amato, Luigi Ciampo, Eliana Sferra, Antonio Molino, Giulia Pelaia, Alessandro Vatrella
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 3, p 2455 (2023)
Add-on biological therapy has proven to be effective in many patients with severe eosinophilic asthma. In this observational multicenter retrospective study, we report the results obtained with mepolizumab and benralizumab in severe asthmatics treate
Externí odkaz:
https://doaj.org/article/86a4c53a252449a2b07aeb80bc94b675
Autor:
Alessandro Vatrella, Angelantonio Maglio, Corrado Pelaia, Luigi Ciampo, Giulia Pelaia, Carolina Vitale
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2181 (2022)
Severe asthma is characterized by different endotypes driven by complex pathologic mechanisms. In most patients with both allergic and non-allergic asthma, predominant eosinophilic airway inflammation is present. Given the central role of eosinophili
Externí odkaz:
https://doaj.org/article/f03662be0c63488cbfb2e037f84f8e60
Autor:
Corrado Pelaia, Giulia Pelaia, Claudia Crimi, Angelantonio Maglio, Giuseppe Armentaro, Cecilia Calabrese, Angela Sciacqua, Luca Gallelli, Alessandro Vatrella
Publikováno v:
Vaccines, Vol 10, Iss 6, p 974 (2022)
Interleukin-4 (IL-4) and interleukin-13 (IL-13) are key cytokines involved in the pathophysiology of both immune-inflammatory and structural changes underlying type 2 asthma. IL-4 plays a pivotal role in Th2 cell polarization, immunoglobulin E (IgE)
Externí odkaz:
https://doaj.org/article/de481065745741429b8a2d324c4ac5aa