Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Alessandro, Prestipino"'
Autor:
Alessandro Prestipino, Robert Zeiser
Publikováno v:
Science Translational Medicine. 11
Treatment with immune checkpoint inhibitors targeting programmed death receptor-1 (PD-1) or programmed death ligand-1 (PD-L1) is effective in many cancer types. Tumors harboring specific mutations modulate antitumor immune responses through the PD-1/
Autor:
Khalid Shoumariyeh, Robert Zeiser, Sivahari P. Gorantla, Sebastian Halbach, Frederike A. Hartl, Alica J. Emhardt, Julius Wehrle, Jonas S. Jutzi, Sebastian Fuchs, Ioanna Triviai, Sandra Duquesne, Michael Hettich, Annette Schmitt-Graeff, Eliana Ruggiero, Susana Minguet, Wolfgang Melchinger, Jürgen Finke, Chiara Bonini, Nicolaus Kröger, Pia Veratti, Anna Lena Illert, Bruce R. Blazar, Melanie Boerries, Mark Bartholomä, Teresa Poggio, Geoffrey R. Hill, Steven W. Lane, Gabriele Niedermann, Petya Apostolova, Slavica Vuckovic, Nikolas von Bubnoff, Konrad Aumann, Hauke Busch, Stephan Ehl, Florian H. Heidel, Sandra Pennisi, Dietmar Pfeifer, Justus Duyster, Cornelius Miething, David O’Sullivan, Marie Follo, Lukas Braun, Christine Dierks, Heiko Becker, Heike L. Pahl, Jan Rohr, Tilman Brummer, Alessandro Prestipino, Erika L. Pearce
Publikováno v:
Science Translational Medicine
Science translational medicine : integrating medicine and science / American Association for the Advancement of Science
Science translational medicine : integrating medicine and science / American Association for the Advancement of Science
Recent evidence has revealed that oncogenic mutations may confer immune escape. A better understanding of how an oncogenic mutation affects immunosuppressive programmed death ligand 1 (PD-L1) expression may help in developing new therapeutic strategi
Autor:
Annette Schmitt-Graeff, Robert Zeiser, Joseena Iype, Gabriele Prinz, Jürgen Finke, Benjamin A. H. Smith, Alessandro Prestipino, Dietmar Pfeifer, Sophia Chen, Yvonne Beck, Marco Idzko, Justus Duyster, Sebastian Grundmann
Publikováno v:
Blood. 126:103-112
The successful treatment of acute leukemias with allogeneic hematopoietic cell transplantation (allo-HCT) is limited by acute graft-versus-host disease (GVHD). Because microRNA-155 (miR-155) regulates activation of the innate immune system, we aimed
Autor:
Alessandro, Prestipino, Alica J, Emhardt, Konrad, Aumann, David, O'Sullivan, Sivahari P, Gorantla, Sandra, Duquesne, Wolfgang, Melchinger, Lukas, Braun, Slavica, Vuckovic, Melanie, Boerries, Hauke, Busch, Sebastian, Halbach, Sandra, Pennisi, Teresa, Poggio, Petya, Apostolova, Pia, Veratti, Michael, Hettich, Gabriele, Niedermann, Mark, Bartholomä, Khalid, Shoumariyeh, Jonas S, Jutzi, Julius, Wehrle, Christine, Dierks, Heiko, Becker, Annette, Schmitt-Graeff, Marie, Follo, Dietmar, Pfeifer, Jan, Rohr, Sebastian, Fuchs, Stephan, Ehl, Frederike A, Hartl, Susana, Minguet, Cornelius, Miething, Florian H, Heidel, Nicolaus, Kröger, Ioanna, Triviai, Tilman, Brummer, Jürgen, Finke, Anna L, Illert, Eliana, Ruggiero, Chiara, Bonini, Justus, Duyster, Heike L, Pahl, Steven W, Lane, Geoffrey R, Hill, Bruce R, Blazar, Nikolas, von Bubnoff, Erika L, Pearce, Robert, Zeiser
Publikováno v:
Science translational medicine. 10(429)
Recent evidence has revealed that oncogenic mutations may confer immune escape. A better understanding of how an oncogenic mutation affects immunosuppressive PD-L1 expression may help in developing new therapeutic strategies. Here, we show that oncog
Autor:
Anne Schönle, Gabriele Prinz, Anne Kathrin Hechinger, Frederike A. Hartl, Kerstin Fehrenbach, Keli Hippen, Jan Mentzel, Justus Duyster, Sebastian A. Wohlfeil, Susana Minguet, Ann Katrin Ruess, Dietmar Pfeifer, Robert Zeiser, Annette Schmitt-Graeff, Miguel A. del Pozo, Theresa Nöltner, Wolfgang Melchinger, Alessandro Prestipino, Katharina S. Rauch, Petya Apostolova, Marta C. Guadamillas, Marie Follo, Kristina Schachtrup, Bruce R. Blazar
Publikováno v:
Blood
Caveolin-1 (Cav-1) is a key organizer of membrane specializations and a scaffold protein that regulates signaling in multiple cell types. We found increased Cav-1 expression in human and murine T cells after allogeneic hematopoietic cell transplantat