Polymeric Microbubble Shell Engineering: Microporosity as a Key Factor to Enhance Ultrasound Imaging and Drug Delivery Performance

Autor: Mirjavad Moosavifar, Roman A. Barmin, Elena Rama, Anne Rix, Rustam A. Gumerov, Thomas Lisson, Céline Bastard, Stephan Rütten, Noah Avraham‐Radermacher, Jens Koehler, Michael Pohl, Vedangi Kulkarni, Jasmin Baier, Susanne Koletnik, Rui Zhang, Anshuman Dasgupta, Alessandro Motta, Marek Weiler, Igor I. Potemkin, Georg Schmitz, Fabian Kiessling, Twan Lammers, Roger M. Pallares

Publikováno v: Advanced Science, Vol 11, Iss 40, Pp n/a-n/a (2024)

Abstract Microbubbles (MB) are widely used as contrast agents for ultrasound (US) imaging and US‐enhanced drug delivery. Polymeric MB are highly suitable for these applications because of their acoustic responsiveness, high drug loading capability,

Externí odkaz: https://doaj.org/article/8c947ff4567a40059a9e342acc93ab13

Successful Versus Failed Transition From Controlled Ventilation to Pressure Support Ventilation in COVID-19 Patients: A Retrospective Cohort Study

Autor: Melisa Polo Friz, MD, Emanuele Rezoagli, MD, Bijan Safaee Fakhr, MD, Gaetano Florio, MD, Eleonora Carlesso, MS, Riccardo Giudici, MD, Clarissa Forlini, MD, Francesca Tardini, MD, Thomas Langer, MD, Matteo Laratta, MD, Giampaolo Casella, MD, Andrea Forastieri Molinari, MD, Alessandro Protti, MD, Maurizio Cecconi, MD, Luca Cabrini, MD, Emanuela Biagioni, MD, Angela Berselli, MD, Lucia Mirabella, MD, Tommaso Tonetti, MD, Edoardo De Robertis, MD, Domenico Luca Grieco, MD, Massimo Antonelli, MD, Giuseppe Citerio, MD, Roberto Fumagalli, MD, Giuseppe Foti, MD, Alberto Zanella, MD, Giacomo Grasselli, MD, Giacomo Bellani, MD, for the COVID-19 Lombardy ICU Network, Amedeo Guzzardella, Luigi Vivona, Vittorio Scaravilli, Sebastiano Colombo, Alessio Cacioppola, Matteo Brioni, Clarissa Forlini, Francesca Tardini, Thomas Langer, Matteo Laratta, Giampaolo Casella, Maria Marsili, Serena Stropeni, Valentina Cordolcini, Francesco Crimella, Alessandro Santini, Massimiliano Greco, Michele Ferrari, Giacomo Iapichino, Paolo Severgnini, Davide Maraggia, Dario Gasberti, Alessandro Motta, Irene Coloretti, Stefano Busani, Martina Tosi, Ilenia Gatto, Carlo Montalto, Alberto Biondo, Ziad Algamain, Valentina Alaimo, Livio Tullo, Francesco Paolo Padovano, Giacinto Pizzilli, Irene Cavalli, Rachele Simonte, Davide Valeri, Gennaro DePascale, Simone Carelli, Valentina Noseda, Giacomo Cimicchi, Gaia Ottonello, Rossano Ghedin, Francesco Giacalone, Tiziana Bove, Francesco Meroi, Sara Scapol, Laura Pistidda, Angela Muretti, Savino Spadaro, Gaetano Scaramuzzo, Gioconda Ferraro, Giuseppe Gagliardi, Giovanni Sabbatini, Angelo Pezzi, Gabriele Sales, Giorgia Montrucchio, Andrea Carsetti, Federico Longhini, Maria Vargas, Plinio Calligaro, Ilaria Mariani, Vanessa Zambelli, Beatrice Noè, Filippo Serra

Publikováno v: Critical Care Explorations, Vol 6, Iss 2, p e1039 (2024)

OBJECTIVES:. In patients with COVID-19 respiratory failure, controlled mechanical ventilation (CMV) is often necessary during the acute phases of the disease. Weaning from CMV to pressure support ventilation (PSV) is a key objective when the patient�

Externí odkaz: https://doaj.org/article/4b6ae8e021cf455fba1cf96f2a53600a

Unlocking the Stability of Reduced Graphene Oxide Nanosheets in Biological Media via Use of Sodium Ascorbate

Autor: Francesco Amato, Giordano Perini, Ginevra Friggeri, Alberto Augello, Alessandro Motta, Leonardo Giaccari, Robertino Zanoni, Marco De Spirito, Valentina Palmieri, Andrea Giacomo Marrani, Massimiliano Papi

Publikováno v: Advanced Materials Interfaces, Vol 10, Iss 22, Pp n/a-n/a (2023)

Abstract Graphene oxide and reduced graphene oxide (RGO) are carbon bidimensional nanomaterials largely exploited in biomedicine. Their unique interactions with eukaryotic and prokaryotic cells are used to obtain precise intracellular delivery, to cr

Externí odkaz: https://doaj.org/article/ce8adee4784f478ab22794af0cd70cc1

Treatments for intracranial hypertension in acute brain-injured patients: grading, timing, and association with outcome. Data from the SYNAPSE-ICU study

Autor: Robba, Chiara, Graziano, Francesca, Guglielmi, Angelo, Rebora, Paola, Galimberti, Stefania, Taccone, Fabio S, Citerio, Giuseppe, Walter Videtta, Gustavo Domeniconi, María Estrella Giménez, Mariela Fumale, Edgar Daniel Amundarain, Matias Casanova, Michael Reade, Elizabeth Hallt, David Pearson, Ian Seppelt, Raimund Helbok, Valery Davidovich, Geert Meyfroidt, Ilaria Alice Crippa, Liese Mebis, Patrick Biston, Stijn Van De Velde, Glorieux Denis, Pedro Kurtz, Samia Yasin Wayhs, Mypinder Sekhon, Donald Griesdale, Andrea Rigamonti, José Miguel Montes, Rodrigo Pérez-Araos, Jorge H Mejia-Mantilla, Andrés Gempeler, Ray Mendoza, Natasa Kovac, Hedgar Berty Gutiérrez, Vera Spatenkova, Marek Fencl, Roman Gal, Ondrej Hrdy, Kamil Vrbica, Josef Skola, Eva Provaznikova, Jakub Kletecka, Pavel Lavicka, Piergiorgio Bresil, Marianne Levin, Josefine Thomsen, Thomas Egmose Larsen, Henrik Westy Hoffmeyer, Morten Olskjaer Holm, Jesper Borg Andersen, Birgitte Majholm, Margit Smitt, Heidi Shil Eddelien, Manuel Jibaja, Freddy Maldonado, María Fernanda García, Karim Asehnoune, Bertrand Pons, Gérard Audibert, Manon Lucca, Guillaume Besch, Pierluigi Banco, Raphael Cinotti, Hervé Q Uintard, Benjamin Soyer, Anais Caillard, Clement Gakuba, Romain Sonneville, Stefan Wolf, Kristina Fuest, Lea Albrecht, Sarah Grotheer, Sandro M Krieg, Stefan J Schaller, Charikleia Vrettou, Eftychia Kontoudaki, Anna Efthymiou, Elena Palli, Demosthenes Makris, Chrysi Diakaki, Christina Iasonidou, Aikaterini Dimoula, Georgios Koukoulitsios, George Kyriazopoulos, Nikolas Pantelas, Syragoula Tsikriki, Electra Eleni Stamou, Achileas Giannopoulos, Eleni Mouloudi, Ping Shum Hoi, Yan Chan Cheuk, Hewa Kandamby Darshana, Krisztián Tánczos, Gabor Nardai, Zoltan Szentkereszty, Harsh Sapra, Deepak Gupta, Kaveri Sharma, Saurabh Anand, Ankur Luthra, Summit Bloria, Rajeev Chauhan, Nidhi Panda, Ahmad Ozair, Bram Kilapong, Anass Alsudani, Giuseppe Citerio, Alessandra Soragni, Alessandro Motta, Andrea Marudi, Elisabetta Bertellini, Anselmo Caricato, Camilla Gelormini, Eleonora Ioannoni, Eleonora Stival, Serena Silva, Federico Pozzi, Iole Brunetti, Andrea Cortegiani, Edoardo Picetti, Federico Villa, Italo Calamai, Maria Chiara Casadio, Maria Concetta Quartarone, Marzia Grandis, Federico Magni, Silvia Del Bianco, Claudia Bonetti, Virginia Buldini, Aimone Giugni, Simone Maria Zerbi, Marco Carbonara, Antonella Cotoia, Antonio Izzi, Olegs Sabelnikovs, Muhammed Elhadi, Hazem Ahmed, Silvio A Ñamendys Silva, Gilberto Adrian Gasca López, Gentle S Shrestha, Shirish Maskey, Tamanna Bajracharya, Khadka Nilam, Prakash Kafle, Laleet Rajbanshi, Yam Bahadur Roka, Olufemi Idowu, Khan Muhammad Mukhtar, Juan Luis Pinedo Portilla, Klaudyna Kojder, Irene Aragao, Ricardo Freitas, Marco Simoes, Dario Batista, Cecília Pacheco, Fátima Assunção, Luís Lencastre, Pedro Cavaleiro, Mohamed Abdelaty, Alex Gritsan, Sergey Khomiakov Sergey, Dovbysh Nikolay, Yaseen Arabi, Primoz Gradisek, Petra Forjan, Mara Škoti, Suada Filekovic Ribaric, Nataša Milivojevic, Sergeja Kozar, Rafael Badenes, Aaron Blandino Ortiz, Mikel Celaya Lopez, Laura Galarza, Luisa Corral, Africa Lores, Ricard Soley, Laura Pariente, Pablo López Ojeda, Maria Dolores Arias Verdu, Luis Javier Yuste Dominguez, Maria Isabel Gonzalez Perez, Mireia Anglada, Patricia Duque, Ainhoa Serrano, Berta Monleon, Vanessa Blazquez, Mauro Oddo, Samia Abed Maillard, Paola Morelli, John-Paul Miroz, Eva Favre, Walid Sellami, Massimo Lamperti, Jamil Dibu, Richard Sivities, Angelos Kolias, Chris Thompson, Christopher Hawthorne, Justin Roberts, Lara Prisco, Roger Lightfoot, Josè I Suarez, Luci Rivera-Lara, Susanne Muehlschlegel, Juan Padilla, Sanjeev Sivakumar, Daiwai Olson

Publikováno v: Intensive Care Medicine. 49:50-61

Purpose: Uncertainties remain about the safety and efficacy of therapies for managing intracranial hypertension in acute brain injured (ABI) patients. This study aims to describe the therapeutical approaches used in ABI, with/without intracranial pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f9aacc60df8cd801ce82fe7f350f8f1a
https://doi.org/10.1007/s00134-022-06937-1

Blockchain Applications in the Agri-Food Domain: The First Wave

Autor: Giorgio Alessandro Motta, Bedir Tekinerdogan, Ioannis N. Athanasiadis

Publikováno v: Frontiers in Blockchain, Vol 3 (2020)

This study aims to investigate the application potential of blockchain technology in the agri-food industry, by following a case study approach focused on the early adopter companies. As the topic is emerging, there are not enough academic papers ava

Externí odkaz: https://doaj.org/article/023ccd067a0345c6a12a2e3956408cd5