Zobrazeno 1 - 10
of 82
pro vyhledávání: '"Alessandro, Canella"'
Autor:
Matthew S. Stratton, José Alberto López-Domínguez, Alessandro Canella, Jon J. Ramsey, Gino A. Cortopassi
Publikováno v:
The Journal of Nutrition, Health and Aging, Vol 29, Iss 2, Pp 100427- (2025)
Background: Aging is associated with multiple neurodegenerative conditions that severely limit quality of life and can shorten lifespan. Studies in rodents indicate that in addition to extending lifespan, the ketogenic diet (KD) improves cognitive fu
Externí odkaz:
https://doaj.org/article/1b680adc0223438a824e9d029769db19
Autor:
Alessandro Canella, Mykyta Artomov, Aleksandr Ukhatov, Sakthi Rajendran, Phillip Perez, Uksha Saini, Jack Hedberg, Kevin Cassady, Prajwal Rajappa
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 3, Pp 200861- (2024)
High-grade gliomas (HGGs) and glioblastomas (GBMs) are the most aggressive and lethal brain tumors. The current standard of care (SOC) includes gross safe surgical resection followed by chemoradiotherapy. The main chemotherapeutic agents are the DNA-
Externí odkaz:
https://doaj.org/article/eba8ac1afd6b42618a79843c161da767
Autor:
Alessandro Canella, Matthew Nazzaro, Mykyta Artomov, Lakshmi Prakruthi Rao Venkata, Diana Thomas, Justin Lyberger, Aleksandr Ukhatov, Yao Lulu Xing, Katherine Miller, Gregory Behbehani, Nduka M. Amankulor, Claudia Katharina Petritsch, Prajwal Rajappa
Publikováno v:
Molecular Therapy: Oncology, Vol 32, Iss 2, Pp 200808- (2024)
Low-grade glioma (LGG) is the most common brain tumor affecting pediatric patients (pLGG) and BRAF mutations constitute the most frequent genetic alterations. Within the spectrum of pLGGs, approximately 70%–80% of pediatric patients diagnosed with
Externí odkaz:
https://doaj.org/article/f87e862d06ba4cdf9ce8b38527e451cf
Autor:
Matthew Nazzaro, Alessandro Canella, Claire Schmitt, Abigail Haffey, Giovanni Nigita, Gregory K Behbehani, Prajwal Rajappa
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss Suppl 1 (2023)
Externí odkaz:
https://doaj.org/article/1828a68109d343cf9cf106f4b381f851
Publikováno v:
HemaSphere, Vol 7, p e8321284 (2023)
Externí odkaz:
https://doaj.org/article/dc48466ec3a24b65868a57456b56af7a
Autor:
Alessandro Canella, Matthew Nazzaro, Sakthi Rajendran, Claire Schmitt, Abigail Haffey, Giovanni Nigita, Diana Thomas, Justin M. Lyberger, Gregory K. Behbehani, Nduka M. Amankulor, Elaine R. Mardis, Timothy P. Cripe, Prajwal Rajappa
Publikováno v:
Cell Reports, Vol 42, Iss 8, Pp 112891- (2023)
Summary: Gliomas are one of the leading causes of cancer-related death in the adolescent and young adult (AYA) population. Two-thirds of AYA glioma patients are affected by low-grade gliomas (LGGs), but there are no specific treatments. Malignant pro
Externí odkaz:
https://doaj.org/article/30306653fadb443a81cc1ac3965bc482
Autor:
Sakthi Rajendran, Yang Hu, Alessandro Canella, Clayton Peterson, Amy Gross, Maren Cam, Matthew Nazzaro, Abigail Haffey, Akdes Serin-Harmanci, Rosario Distefano, Giovanni Nigita, Wesley Wang, Daniel Kreatsoulas, Zihai Li, Jesse A. Sepeda, Andrew Sas, Mark E. Hester, Katherine E. Miller, Olivier Elemento, Ryan D. Roberts, Eric C. Holland, Ganesh Rao, Elaine R. Mardis, Prajwal Rajappa
Publikováno v:
Cell Reports, Vol 42, Iss 3, Pp 112197- (2023)
Summary: Recent studies have shown the importance of the dynamic tumor microenvironment (TME) in high-grade gliomas (HGGs). In particular, myeloid cells are known to mediate immunosuppression in glioma; however, it is still unclear if myeloid cells p
Externí odkaz:
https://doaj.org/article/4c475f0d1a224421a34de4bf6fa862d6
Autor:
Youssef Youssef, Vrajesh Karkhanis, Wing Keung Chan, Frankie Jeney, Alessandro Canella, Xiaoli Zhang, Shelby Sloan, Alexander Prouty, JoBeth Helmig-Mason, Liudmyla Tsyba, Walter Hanel, Xuguang Zheng, Pu Zhang, Ji-Hyun Chung, David M. Lucas, Zachary Kauffman, Karilyn Larkin, Anne M. Strohecker, Hatice G. Ozer, Rosa Lapalombella, Hui Zhou, Zijun Y. Xu-Monette, Ken H. Young, Ruolan Han, Elmar Nurmemmedov, Gerard Nuovo, Kami Maddocks, John C. Byrd, Robert A. Baiocchi, Lapo Alinari
Publikováno v:
Haematologica, Vol 106, Iss 11 (2020)
Diffuse large B-cell lymphoma (DLBCL) is the most common non- Hodgkin lymphoma and is characterized by a remarkable heterogeneity with diverse variants that can be identified histologically and molecularly. Large-scale gene expression profiling studi
Externí odkaz:
https://doaj.org/article/c8e57782db32404a86671cb394c3f877
Autor:
Flavia Pichiorri, Craig C. Hofmeister, Balveen Kaur, Robert Baiocchi, John C. Byrd, Don M. Benson, Pearlly Yan, Alena Cristina Jaime-Ramirez, Matthew Old, Joseph Badway, Emily Smith, Alessandro Canella, Sarah Y. Schlotter, Xiaokui Mo, Gerard J. Nuovo, Douglas W. Sborov, Enrico Caserta, Andrew Stiff
Supplementary Fig. S1. Therapeutic efficacy of RV and HDACi against cancer B cells; Supplementary Fig. S2. HDACi increase JAM-1 expression without affecting cell viability; Supplementary Fig. S3. RV+HDACi display synergistic anti-myeloma activity; Su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::108dc400925926059cd6d97a1b4b5039
https://doi.org/10.1158/1535-7163.22508208.v1
https://doi.org/10.1158/1535-7163.22508208.v1
Autor:
Siska Van Belle, Sara El Ashkar, Kateřina Čermáková, Filip Matthijssens, Steven Goossens, Alessandro Canella, Courtney H. Hodges, Frauke Christ, Jan De Rijck, Pieter Van Vlierberghe, Václav Veverka, Zeger Debyser
Publikováno v:
Cells, Vol 10, Iss 1, p 192 (2021)
HDGF-related protein 2 (HRP-2) is a member of the Hepatoma-Derived Growth Factor-related protein family that harbors the structured PWWP and Integrase Binding Domain, known to associate with methylated histone tails or cellular and viral proteins, re
Externí odkaz:
https://doaj.org/article/cdb1cb06792347bdb48baa1a2f296fdc