Zobrazeno 1 - 10
of 112
pro vyhledávání: '"Alessandra Zingoni"'
Autor:
Serena Renzi, Luca Digiacomo, Daniela Pozzi, Erica Quagliarini, Elisabetta Vulpis, Maria Valeria Giuli, Angelica Mancusi, Bianca Natiello, Maria Gemma Pignataro, Gianluca Canettieri, Laura Di Magno, Luca Pesce, Valentina De Lorenzi, Samuele Ghignoli, Luisa Loconte, Carmela Maria Montone, Anna Laura Capriotti, Aldo Laganà, Carmine Nicoletti, Heinz Amenitsch, Marco Rossi, Francesco Mura, Giacomo Parisi, Francesco Cardarelli, Alessandra Zingoni, Saula Checquolo, Giulio Caracciolo
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)
Abstract Lipid nanoparticles (LNPs) play a crucial role in addressing genetic disorders, and cancer, and combating pandemics such as COVID-19 and its variants. Yet, the ability of LNPs to effectively encapsulate large-size DNA molecules remains elusi
Externí odkaz:
https://doaj.org/article/0ac4519bb8ec417189f0144fcc73185a
Autor:
Alessandra Zingoni, Fabrizio Antonangeli, Silvano Sozzani, Angela Santoni, Marco Cippitelli, Alessandra Soriani
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Cancer progression is continuously controlled by the immune system which can identify and destroy nascent tumor cells or inhibit metastatic spreading. However, the immune system and its deregulated activity in the tumor microenvironment can
Externí odkaz:
https://doaj.org/article/273e08df360c4f20bb398b4a6117fc3d
Autor:
Lorenzo Cuollo, Samuele Di Cristofano, Annamaria Sandomenico, Emanuela Iaccarino, Angela Oliver, Alessandra Zingoni, Marco Cippitelli, Cinzia Fionda, Sara Petillo, Andrea Kosta, Valentina Tassinari, Maria Teresa Petrucci, Francesca Fazio, Menotti Ruvo, Angela Santoni, Domenico Raimondo, Alessandra Soriani
Publikováno v:
iScience, Vol 27, Iss 5, Pp 109814- (2024)
Summary: 2′3′-cyclic guanosine monophosphate–adenosine monophosphate (cGAMP) is the endogenous agonist of STING; as such, cGAMP has powerful immunostimulatory activity, due to its capacity to stimulate type I interferon-mediated immunity. Recen
Externí odkaz:
https://doaj.org/article/d8e6f044263540b99c87c79122f65561
Autor:
Sara Petillo, Elena Sproviero, Luisa Loconte, Lorenzo Cuollo, Alessandra Zingoni, Rosa Molfetta, Cinzia Fionda, Alessandra Soriani, Cristina Cerboni, Maria Teresa Petrucci, Francesca Fazio, Rossella Paolini, Angela Santoni, Marco Cippitelli
Publikováno v:
Cell Death and Disease, Vol 14, Iss 7, Pp 1-14 (2023)
Abstract Natural Killer (NK) cells act as important regulators in the development and progression of hematological malignancies and their suppressor activity against Multiple Myeloma (MM) cells has been confirmed in many studies. Significant changes
Externí odkaz:
https://doaj.org/article/22752b3441544783949b7cd7088d7d80
Autor:
Alessandra Zingoni, Teresa Bellón
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/80f1c0ee0cfb4d96b57d1305cb43ffdc
Autor:
Alessandra Zingoni, Marco Cippitelli
Publikováno v:
Clinical and Translational Discovery, Vol 2, Iss 4, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/ad6646bccc7c436f97b3f22caf20bef0
Autor:
Sara Petillo, Cristina Capuano, Rosa Molfetta, Cinzia Fionda, Abdelilah Mekhloufi, Chiara Pighi, Fabrizio Antonangeli, Alessandra Zingoni, Alessandra Soriani, Maria Teresa Petrucci, Ricciarda Galandrini, Rossella Paolini, Angela Santoni, Marco Cippitelli
Publikováno v:
Cell Death and Disease, Vol 12, Iss 9, Pp 1-13 (2021)
Abstract Multiple Myeloma (MM) is an incurable hematologic malignancy of terminally differentiated plasma cells (PCs), where immune interactions play a key role in the control of cancer cell growth and survival. In particular, MM is characterized by
Externí odkaz:
https://doaj.org/article/027a95b214af4c66bd8400071bbc0d06
Autor:
Andrea Kosta, Abdelilah Mekhloufi, Lorenzo Lucantonio, Alessandra Zingoni, Alessandra Soriani, Marco Cippitelli, Angela Gismondi, Francesca Fazio, Maria Teresa Petrucci, Angela Santoni, Helena Stabile, Cinzia Fionda
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
NKG2D ligands play a relevant role in Natural Killer (NK) cell -mediated immune surveillance of multiple myeloma (MM). Different levels of regulation control the expression of these molecules at cell surface. A number of oncogenic proteins and miRNAs
Externí odkaz:
https://doaj.org/article/25869058e7b14f3b8801c581e1b362a1
Autor:
Elisabetta Vulpis, Luisa Loconte, Chiara Cassone, Fabrizio Antonangeli, Giulio Caracciolo, Laura Masuelli, Francesca Fazio, Maria Teresa Petrucci, Cinzia Fionda, Alessandra Soriani, Cristina Cerboni, Marco Cippitelli, Angela Santoni, Alessandra Zingoni
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 11, p 9467 (2023)
Natural Killer (NK) cells are innate cytotoxic lymphoid cells that play a crucial role in cancer immunosurveillance. NKG2D is an activating receptor that binds to MIC and ULBP molecules typically induced on damaged, transformed, or infected cells. Th
Externí odkaz:
https://doaj.org/article/554f01c0d85d4df283ff6af925ac9a69
Autor:
Elisabetta Vulpis, Lorenzo Cuollo, Cristiana Borrelli, Fabrizio Antonangeli, Laura Masuelli, Marco Cippitelli, Cinzia Fionda, Giulio Caracciolo, Maria Teresa Petrucci, Angela Santoni, Alessandra Zingoni, Alessandra Soriani
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 7, p 6862 (2023)
The success of senescence-based anticancer therapies relies on their anti-proliferative power and on their ability to trigger anti-tumor immune responses. Indeed, genotoxic drug-induced senescence increases the expression of NK cell-activating ligand
Externí odkaz:
https://doaj.org/article/b297c76528cd418487db6cfcee213a05