Effector T-cells are expanded in systemic lupus erythematosus patients with high disease activity and damage indexes

Autor: Alessandra Zanola, Silvia Piantoni, Angela Tincani, Francesca Regola, Laura Andreoli, Francesca Dall'Ara, Paolo Airò

Publikováno v: Lupus. 27:143-149

Background and objectives T-cell activation may be one of the pathogenic mechanisms of systemic lupus erythematosus (SLE). After repeated antigenic stimulation, T-cells undergo different modifications, leading to the differentiation into effector mem

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::524622ae2fbb93f1e2377c5bc062d921
https://doi.org/10.1177/0961203317722848

Sine causa tetraparesis

Autor: Giulio Gualdi, Luisa Lorenzi, Gillian I. Rice, Jessica Galli, Donatella Vairo, Marzia Mortilla, Fabio Facchetti, Marco Cattalini, Francesco Gavazzi, Marika Bianchi, Cristina Cereda, Silvia Giliani, Antonella Meini, Elisa Fazzi, Alessandra Zanola, Micaela De Simone, Raffaele Badolato, Micaela Fredi, Rosalba Monica Ferraro, Nice Carabellese, Laura Andreoli, Marialuisa Valente, Simona Orcesi, Jessica Garau, Angela Tincani

Publikováno v: AGS study group 2018, ' Sine causa tetraparesis : A pilot study on its possible relationship with interferon signature analysis and Aicardi Goutières syndrome related genes analysis ', Medicine (Philadelphia), vol. 97, no. 52, pp. e13893 . https://doi.org/10.1097/MD.0000000000013893
Medicine

Tetraparesis is usually due to cerebral palsy (CP), inborn errors of metabolism, neurogenetic disorders and spinal cord lesions. However, literature data reported that about 10% of children with tetraparesis show a negative/non-specific neuroradiolog

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b6a97e3c0472f13a457743df87fb78b8
https://doi.org/10.1097/md.0000000000013893

Phenotype modifications of T-cells and their shift toward a Th2 response in patients with systemic lupus erythematosus supplemented with different monthly regimens of vitamin D

Autor: Mirko Scarsi, Angela Tincani, Francesca Dall'Ara, C Pizzorni, Maurizio Cutolo, Laura Andreoli, Paolo Airò, Alessandra Zanola, Silvia Piantoni

Publikováno v: Lupus. 24(4-5)

Background Vitamin D receptor is constitutively expressed on the lymphocyte surface. Recent studies highlight that vitamin D may exert actions on T-cells, inhibiting Th1 and Th17 response and enhancing Th2 and T-regulatory (T-reg) function. Methods T

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb7d6d358aa1c58068fea388f2966d5c
https://pubmed.ncbi.nlm.nih.gov/25801892

MURC/cavin-4 is co-expressed with Caveolin-3 in rhabdomyosarcoma tumors and its silencing prevents myogenic differentiation in the human embryonal RD cell line

Autor: Marika Vezzoli, Charles Keller, Manuela Cominelli, Pietro Luigi Poliani, Alessandra Zanola, Chiara Fiorentini, Giovanni Tulipano, Silvia Codenotti, Alessandro Fanzani, Robert G. Parton, Marina Colombi, Harriet P. Lo, Eugenio Monti, Federica Bono, Fiorella Faggi, Nicola Chiarelli

Publikováno v: PLoS ONE
PLoS ONE, Vol 10, Iss 6, p e0130287 (2015)

The purpose of this study was to investigate whether MURC/cavin-4, a plasma membrane and Z-line associated protein exhibiting an overlapping distribution with Caveolin-3 (Cav-3) in heart and muscle tissues, may be expressed and play a role in rhabdom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32f7fe54c1cfbfa15f8958f0d3e09a3a
http://hdl.handle.net/11379/460091

Clinical characterization of antiphospholipid syndrome by detection of IgG antibodies against β2 -glycoprotein i domain 1 and domain 4/5: ratio of anti-domain 1 to anti-domain 4/5 as a useful new biomarker for antiphospholipid syndrome

Autor: Laura Andreoli, Maria Gerosa, Pier Luigi Meroni, M. Orietta Borghi, Angela Tincani, Michael Mahler, Alessandra Zanola, F. Allegri, Claudia Grossi, Cecilia Beatrice Chighizola, Cecilia Nalli, Francesca Pregnolato, Gary L. Norman

Publikováno v: Arthritisrheumatology (Hoboken, N.J.). 67(8)

Objective It has been suggested that only antibodies against domain 1 (D1) of β2 -glycoprotein I (β2 GPI) are pathogenic and diagnostic. The role of antibodies against other β2 GPI domains is still debated. This study was undertaken to evaluate th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f335d47894586017763def9e96ce1146
https://pubmed.ncbi.nlm.nih.gov/25939498