Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Alessandra Morselli"'
Autor:
Michela Sgarzi, Martina Mazzeschi, Spartaco Santi, Elisa Montacci, Tito Panciera, Enea Ferlizza, Cinzia Girone, Alessandra Morselli, Valerio Gelfo, Rikke Sofie Kuhre, Carola Cavallo, Sabrina Valente, Gianandrea Pasquinelli, Balazs Győrffy, Gabriele D’Uva, Donatella Romaniello, Mattia Lauriola
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract Little is known about the signaling network responsible for the organization of the perinuclear actin cap, a recently identified structure holding unique roles in the regulation of nuclear shape and cell directionality. In cancer cells expre
Externí odkaz:
https://doaj.org/article/d950c2436bcb4f8c89114f68ee466fff
Senescence-associated reprogramming induced by interleukin-1 impairs response to EGFR neutralization
Autor:
Donatella Romaniello, Valerio Gelfo, Federica Pagano, Enea Ferlizza, Michela Sgarzi, Martina Mazzeschi, Alessandra Morselli, Carmen Miano, Gabriele D’Uva, Mattia Lauriola
Publikováno v:
Cellular & Molecular Biology Letters, Vol 27, Iss 1, Pp 1-17 (2022)
Abstract Background EGFR targeting is currently the main treatment strategy for metastatic colorectal cancer (mCRC). Results of different clinical trials show that patients with wild-type KRAS and BRAF benefit from anti-EGFR monoclonal antibodies (mo
Externí odkaz:
https://doaj.org/article/21cfe00577034ec4ab62d605220dea79
Autor:
Martina Mazzeschi, Michela Sgarzi, Donatella Romaniello, Valerio Gelfo, Carola Cavallo, Francesca Ambrosi, Alessandra Morselli, Carmen Miano, Noemi Laprovitera, Cinzia Girone, Manuela Ferracin, Spartaco Santi, Karim Rihawi, Andrea Ardizzoni, Michelangelo Fiorentino, Gabriele D’Uva, Balázs Győrffy, Ruth Palmer, Mattia Lauriola
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-18 (2022)
Abstract Background In the last years, several efforts have been made to classify colorectal cancer (CRC) into well-defined molecular subgroups, representing the intrinsic inter-patient heterogeneity, known as Consensus Molecular Subtypes (CMSs). Met
Externí odkaz:
https://doaj.org/article/d15db7c1cf184dda985308a2a46d9b97
Autor:
Donatella Romaniello, Valerio Gelfo, Federica Pagano, Michela Sgarzi, Alessandra Morselli, Cinzia Girone, Daria Maria Filippini, Gabriele D’Uva, Mattia Lauriola
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2023)
Historically, senescence has been considered a safe program in response to multiple stresses in which cells undergo irreversible growth arrest. This process is characterized by morphological and metabolic changes, heterochromatin formation, and secre
Externí odkaz:
https://doaj.org/article/f75c4facecf448f7af8a2eb3226c69b3
Autor:
Carmen Miano, Donatella Romaniello, Martina Mazzeschi, Alessandra Morselli, Silvia Da Pra, Francesca Sacchi, Chiara Bongiovanni, Michela Sgarzi, Elvira Pantano, Mattia Lauriola, Gabriele D’Uva
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
ERBB4 is a tyrosine kinase receptor reported to exert both oncogenic and tumor suppressor activities. These paradoxical effects were suggested to stem from different ERBB4 homo-/hetero-dimers and/or isoforms. By stratifying breast cancer patients for
Externí odkaz:
https://doaj.org/article/923917465bdb47bcad0432af15021d84
Autor:
Enea Ferlizza, Donatella Romaniello, Francesco Borrelli, Federica Pagano, Cinzia Girone, Valerio Gelfo, Rikke Sofie Kuhre, Alessandra Morselli, Martina Mazzeschi, Michela Sgarzi, Daria Maria Filippini, Gabriele D’Uva, Mattia Lauriola
Extracellular vesicles (EVs) are of great interest to study the cellular mechanisms of cancer development and to diagnose and monitor cancer progression. EVs are a highly heterogeneous population of cell derived particles, which include microvesicles
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78d8794c8e7e2df9b97c1cec1419f649
https://hdl.handle.net/11585/928374
https://hdl.handle.net/11585/928374
Autor:
Marcus Bauer, Martina Vetter, Ana Maia, Efstathios Vlachavas, Brigitta Michels, Mireia Berdiel-Acer, Kathleen Schüler, Alessandra Morselli, Manio Skarlatou, Christoph Thomssen, Stefan Wiemann
Publikováno v:
Cancer Research. 82:P1-08
Introduction. Neoadjuvant chemotherapy (NACT) is the standard of care in aggressive breast cancer, including triple negative breast cancer (TNBC). Cytotoxic drugs specifically target proliferating cells, however, patient outcome is variable. Tumor ph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::260e1a47090699168e3032e10698dffc
https://doi.org/10.1158/1538-7445.sabcs21-p1-08-15
https://doi.org/10.1158/1538-7445.sabcs21-p1-08-15
Autor:
Carmen Miano, Alessandra Morselli, Francesca Pontis, Chiara Bongiovanni, Francesca Sacchi, Silvia Da Pra, Donatella Romaniello, Riccardo Tassinari, Michela Sgarzi, Elvira Pantano, Carlo Ventura, Mattia Lauriola, Gabriele D’Uva
Publikováno v:
Cancers; Volume 14; Issue 7; Pages: 1603
ERBB3, also known as HER3, is a tyrosine kinase transmembrane receptor of the ERBB family. Upon binding to neuregulin 1 (NRG1), ERBB3 preferentially dimerizes with HER2 (ERBB2), in turn inducing aggressive features in several cancer types. The analys
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca6810bc248e3c1ce3c1c43050b405d9
https://pubmed.ncbi.nlm.nih.gov/35406375
https://pubmed.ncbi.nlm.nih.gov/35406375
Autor:
Carmen Miano, Donatella Romaniello, Martina Mazzeschi, Alessandra Morselli, Silvia Da Pra, Francesca Sacchi, Chiara Bongiovanni, Michela Sgarzi, Elvira Pantano, Mattia Lauriola, Gabriele D’Uva
Publikováno v:
Frontiers in oncology. 12
ERBB4 is a tyrosine kinase receptor reported to exert both oncogenic and tumor suppressor activities. These paradoxical effects were suggested to stem from different ERBB4 homo-/hetero-dimers and/or isoforms. By stratifying breast cancer patients for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::67ad376c2d092133d5914c0e1e9c1bb4
https://pubmed.ncbi.nlm.nih.gov/35664762
https://pubmed.ncbi.nlm.nih.gov/35664762
Autor:
Valerio Gelfo, Donatella Romaniello, Martina Mazzeschi, Michela Sgarzi, Alessandra Morselli, Enea Ferlizza, Chiara Cappello, Federica Pagano, Moshit Lindzen, Francesco Fazi, Luca Tamagnone, Yosef Yarden and Mattia Lauriola.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______4094::79d6d60d0597f66deebe456e062c7713
http://hdl.handle.net/11585/874872
http://hdl.handle.net/11585/874872