Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Alessandra Milesi-Hallé"'
Autor:
Chavvi Kaushik, Charles M. Glasier, Alessandra Milesi-Hallé, Gregory B. Sharp, Sheila J. Asghar
Publikováno v:
Pediatric Neurology. 47:201-204
Three children with familial hemiplegic migraine presented with right-sided weakness, speech difficulty, altered mental status, and gait abnormalities. These persistent aura signs were accompanied by left-sided slowing and cerebral dysfunction, docum
Autor:
Laura W. Lamps, Sandra S. McCullough, Richard C. Kurten, Alessandra Milesi-Hallé, Jack A. Hinson, Laura P. James, Aliza T. Brown
Publikováno v:
Basic & Clinical Pharmacology & Toxicology. 110:327-334
Up-regulation of vascular endothelial growth factor (VEGF) is important to hepatocyte regeneration in the late stages of acetaminophen (APAP) toxicity in the mouse. This study was conducted to examine the relationship of hypoxia-inducible factor 1α
Autor:
Alessandra Milesi-Hallé, Jack A. Hinson, Aliza T. Brown, Susan M. Abdel-Rahman, Laura P. James, Sandra S. McCullough, Lynda Letzig
Publikováno v:
Chemico-Biological Interactions. 189:222-229
Standard assays to assess acetaminophen (APAP) toxicity in animal models include determination of ALT (alanine aminotransferase) levels and examination of histopathology of liver sections. However, these assays do not reflect the functional capacity
Publikováno v:
Drug and alcohol dependence. 150
Because methamphetamine (METH) pharmacokinetics after single iv doses show significant differences between male and female rats, we hypothesized that pharmacokinetic differences in METH disposition could be a contributing factor to the patterns of ME
Autor:
Elizabeth M. Laurenzana, Howard P. Hendrickson, W. Brooks Gentry, S. Michael Owens, Alessandra Milesi-Hallé
Publikováno v:
Toxicology and Applied Pharmacology. 209:203-213
These studies investigated how (+)-methamphetamine (METH) dose and rat sex affect the pharmacological response to METH in Sprague-Dawley rats. The first set of experiments determined the pharmacokinetics of METH and its pharmacologically active metab
Publikováno v:
Journal of Chromatography B. 806:81-87
The aim of this paper was to develop LC/MS/MS methodology for the determination of methamphetamine (METH) and amphetamine (AMP) using low microliter volumes (20–150 μl) of rat serum and demonstrate the use of this method for the study of serum pha
Autor:
Alessandra, Milesi-Hallé, Sandra, McCullough, Jack A, Hinson, Richard C, Kurten, Laura W, Lamps, Aliza, Brown, Laura P, James
Publikováno v:
Basicclinical pharmacologytoxicology. 110(4)
Up-regulation of vascular endothelial growth factor (VEGF) is important to hepatocyte regeneration in the late stages of acetaminophen (APAP) toxicity in the mouse. The following study was conducted to examine the relationship of hypoxia inducible fa
Autor:
S. Michael Owens, Alessandra Milesi-Hallé, Donald E. McMillan, Elizabeth M. Laurenzana, Kelly Byrnes-Blake
Publikováno v:
Pharmacology, biochemistry, and behavior. 86(1)
(+)-Methamphetamine (METH) and (+)-amphetamine (AMP) are structurally similar drugs that are reported to induce similar pharmacological effects in rats of the same sex. Because pharmacokinetic data suggest female rats should be more affected than mal
Autor:
Kelly Byrnes-Blake, Alessandra Milesi-Hallé, Elizabeth M. Laurenzana, W. Brooks Gentry, S. Michael Owens, D. Keith Williams
Publikováno v:
Drug metabolism and disposition: the biological fate of chemicals. 31(11)
These studies examined the effects of a high-affinity anti-(+)-methamphetamine monoclonal antibody (mAb; KD = 11 nM) on (+)-methamphetamine [(+)-METH] and (+)-amphetamine [(+)-AMP] serum and tissue disposition and serum protein binding following i.v.