Zobrazeno 1 - 10
of 103
pro vyhledávání: '"Alessandra Marconi"'
Autor:
Marika Quadri, Caroline Baudouin, Roberta Lotti, Elisabetta Palazzo, Letizia Campanini, François-Xavier Bernard, Gaëlle Bellemere, Carlo Pincelli, Alessandra Marconi
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5635 (2024)
In the interfollicular epidermis, keratinocyte stem cells (KSC) generate a short-lived population of transit amplifying (TA) cells that undergo terminal differentiation after several cell divisions. Recently, we isolated and characterized a highly pr
Externí odkaz:
https://doaj.org/article/606791977cad44fd91cf758bf7b32f63
Autor:
Giada Zanini, Giulia Bertani, Rosanna Di Tinco, Alessandra Pisciotta, Laura Bertoni, Valentina Selleri, Luigi Generali, Alessandra Marconi, Anna Vittoria Mattioli, Marcello Pinti, Gianluca Carnevale, Milena Nasi
Publikováno v:
Cells, Vol 13, Iss 10, p 836 (2024)
Fibrosis is a pathological condition consisting of a delayed deposition and remodeling of the extracellular matrix (ECM) by fibroblasts. This deregulation is mostly triggered by a chronic stimulus mediated by pro-inflammatory cytokines, such as TNF-
Externí odkaz:
https://doaj.org/article/1a1f959d4f7548988e6ec180b52f6cbb
Autor:
Roberta Lotti, Jennifer E. Hundt, Ralf J. Ludwig, Christoph M. Hammers, Brydon Bennett, Antonino Amato, Alessandra Marconi, Carlo Pincelli
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/045a18521cb1400e87da001ebd519c45
Autor:
Marika Quadri, Natascia Tiso, Francesco Musmeci, Maria I. Morasso, Stephen R. Brooks, Luca Reggiani Bonetti, Rossana Panini, Roberta Lotti, Alessandra Marconi, Carlo Pincelli, Elisabetta Palazzo
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 42, Iss 1, Pp 1-19 (2023)
Abstract Background Cutaneous squamous cell carcinoma (cSCC) is the second most prevalent form of skin cancer, showing a rapid increasing incidence worldwide. Although most cSCC can be cured by surgery, a sizeable number of cases are diagnosed at adv
Externí odkaz:
https://doaj.org/article/13b666a0ba754bbcabd94f8530c27ae2
Autor:
Roberta Lotti, Jennifer E. Hundt, Ralf J. Ludwig, Christoph M. Hammers, Brydon Bennett, Antonino Amato, Alessandra Marconi, Carlo Pincelli
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Pemphigus is a life-threatening, chronic, autoimmune bullous disease affecting both the skin and the mucous membranes. Based on the mainstream concept that blister formation occurs upon binding of autoantibodies to their antigen proteins (desmoglein1
Externí odkaz:
https://doaj.org/article/474c83a7b7be4f86bfc1b06b8d527ea3
Autor:
Marika Quadri, Alessandra Marconi, Simran K. Sandhu, Alexi Kiss, Tatiana Efimova, Elisabetta Palazzo
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
Cutaneous Squamous Cell Carcinoma (cSCC) represents the second most common type of skin cancer, which incidence is continuously increasing worldwide. Given its high frequency, cSCC represents a major public health problem. Therefore, to provide the b
Externí odkaz:
https://doaj.org/article/4d6065dfe6e04f14a937f2f4b73512e8
Autor:
Peter H. Schafer, Mary Adams, Gerald Horan, Francesca Truzzi, Alessandra Marconi, Carlo Pincelli
Publikováno v:
Drugs in R&D, Vol 19, Iss 4, Pp 329-338 (2019)
Abstract Background Apremilast, an oral phosphodiesterase (PDE) 4 inhibitor, has demonstrated efficacy in psoriasis, while its efficacy in atopic dermatitis (AD) was found to be modest. AD is a chronic inflammatory skin disease associated with activa
Externí odkaz:
https://doaj.org/article/6311f234a8234e55843aa86a3e9e665f
Autor:
Matteo Bertesi, Sebastian Fantini, Claudia Alecci, Roberta Lotti, Andrea Martello, Sandra Parenti, Chiara Carretta, Alessandra Marconi, Alexis Grande, Carlo Pincelli, Tommaso Zanocco-Marani
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
The mRNA-destabilizing protein tristetraprolin (TTP), encoded by the ZFP36 gene, is known to be able to end inflammatory responses by directly targeting and destabilizing mRNAs encoding pro-inflammatory cytokines. We analyzed its role in psoriasis, a
Externí odkaz:
https://doaj.org/article/670d9a238aed4ef8ab416caf7d469ac9
Autor:
Roberta Lotti, Claudio Giacinto Atene, Alessandra Marconi, Giulia Di Rocco, L. Reggiani Bonetti, Tommaso Zanocco Marani, Carlo Pincelli
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Pemphigus vulgaris (PV) is a life-threatening mucocutaneous autoimmune blistering disease. It is often associated with autoantibodies to the desmosomal adhesion proteins Desmoglein 3 (DSG3) and Desmoglein 1 (DSG1). Recently, auto-antigens, such as de
Externí odkaz:
https://doaj.org/article/7205133482a549348c5c4bf27921dfc4
Autor:
Emma D. Zanfi, Sebastian Fantini, Roberta Lotti, Matteo Bertesi, Alessandra Marconi, Alexis Grande, Rossella Manfredini, Carlo Pincelli, Tommaso Zanocco-Marani
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 16, p 5692 (2020)
The Wnt/CTNNB1 pathway is often deregulated in epithelial tumors. The ZFP36 gene, encoding the mRNA binding protein Tristetraprolin (TTP), is downregulated in several cancers, where it has been described to behave as a tumor suppressor. By this repor
Externí odkaz:
https://doaj.org/article/10e27e8c93e64322b99e94f6f33b7dea