Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Alessandra Lorenzoni"'
Autor:
Sara Suna Yücel, Walter Stelzer, Alessandra Lorenzoni, Manfred Wozny, Dieter Langosch, Marius K. Lemberg
Publikováno v:
Cell Reports, Vol 26, Iss 11, Pp 3087-3099.e11 (2019)
Summary: Unspliced XBP1 mRNA encodes XBP1u, the transcriptionally inert variant of the unfolded protein response (UPR) transcription factor XBP1s. XBP1u targets its mRNA-ribosome-nascent-chain-complex to the endoplasmic reticulum (ER) to facilitate U
Externí odkaz:
https://doaj.org/article/60d8072ac21a442c9cfc6d10165dcdc1
Autor:
Luisa Maresca, Samuele Lodovichi, Alessandra Lorenzoni, Tiziana Cervelli, Rossella Monaco, Laura Spugnesi, Mariella Tancredi, Elisabetta Falaschi, Katia Zavaglia, Elisabetta Landucci, Manuela Roncella, Caterina Congregati, Angiolo Gadducci, Antonio Giuseppe Naccarato, Maria Adelaide Caligo, Alvaro Galli
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
In this study, we determined if BRCA1 partners involved in DNA double-strand break (DSB) and mismatch repair (MMR) may contribute to breast and ovarian cancer development. Taking advantage the functional conservation of DNA repair pathways between ye
Externí odkaz:
https://doaj.org/article/e639c8c962944410837a5ab480c63c8e
Autor:
Alessandra Lorenzoni, Maria A. Caligo, Francesca Bellè, Samuele Lodovichi, Tiziana Cervelli, Cristina Cozzani, Luisa Maresca, Alvaro Galli
Publikováno v:
Mutagenesis. 35:189-195
Evaluation of the functional impact of germline BRCA1 variants that are likely to be associated to breast and ovarian cancer could help to investigate the mechanism of BRCA1 tumorigenesis. Expression of pathogenic BRCA1 missense variants increased ho
Autor:
Edoardo Bertero, Manrico Balbi, Francesco Chiarella, Francesca Viazzi, Marco Canepa, Roberta Miceli, Pietro Ameri, Roberto Pontremoli, Giorgio Ghigliotti, Claudio Brunelli, Alessandra Lorenzoni
Publikováno v:
Internal and emergency medicine. 14(7)
Guidelines recommend angiotensin-converting enzyme inhibitors (ACEi) and angiotensin II receptor blockers (ARB) for treatment of heart failure with reduced ejection fraction (HFrEF), but these medications are underprescribed in clinical practice. We
Autor:
Sara Suna Yucel, Manfred Wozny, Alessandra Lorenzoni, Walter Stelzer, Dieter Langosch, Marius K. Lemberg
Publikováno v:
Cell Reports, Vol 26, Iss 11, Pp 3087-3099.e11 (2019)
Summary: Unspliced XBP1 mRNA encodes XBP1u, the transcriptionally inert variant of the unfolded protein response (UPR) transcription factor XBP1s. XBP1u targets its mRNA-ribosome-nascent-chain-complex to the endoplasmic reticulum (ER) to facilitate U
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4ccf463579e8bdf2ef990583726d994
Prevalent cardiac, renal and cardiorenal damage in patients with advanced abdominal aortic aneurysms
Autor:
Manrico Balbi, Giovanni Spinella, Bianca Pane, Daniela Verzola, Claudio Brunelli, Francesca Viazzi, Alessandra Lorenzoni, Giorgio Ghigliotti, Pietro Ameri, Silvano Garibaldi, Domenico Palombo, Paolo Spallarossa, Marco Canepa, Riccardo Baldassini, Chiara Barisione
Publikováno v:
Internal and Emergency Medicine. 11:205-212
Chronic kidney disease (CKD), cardiac damage (CD) and the combination of the two are associated with increased morbidity and death in patients admitted to vascular surgery units. We assessed the prevalence of cardiac and renal damage and cardiorenal
Autor:
Alessandra Lorenzoni, Laura Bedin Denardi, Sydney Hartz Alves, Andréa Inês Horn Adams, Juliane Mattiazzi, Scheila Rezende Schaffazick, Luana Mota Ferreira, Letícia Cruz, Sara S. Santos
Publikováno v:
Materials Science and Engineering: C. 33:1389-1394
Clotrimazole is a common choice for the treatment of vulvovaginal infections, but its low solubility and some side effects pose a challenge to its application. This work evaluated the feasibility to formulate clotrimazole-loaded cationic nanocapsules
Autor:
Francesco Torre, Gabriele De Blasi, Marco Canepa, Roberta Miceli, Lorenzo Gigli, Claudio Brunelli, Alessandra Lorenzoni, Pietro Ameri, Gianmarco Secco, Francesco Chiarella
Publikováno v:
World Journal of Cardiology
AIM To assess the prevalence, clinical characteristics and independent prognostic impact of atrial fibrillation (AF) in chronic heart failure (CHF) patients, and the potential protective effect of disease-modifying medications, particularly beta-bloc
Autor:
Thiago Guilherme Schwanz, Joseane de Oliveira Mozzaquatro, Susana Mohr, Joice Sifuentes dos Santos, Alessandra Lorenzoni, Ijoni Hilda Costabeber, Roger Wagner
Publikováno v:
Clinica chimica acta; international journal of clinical chemistry. 451
Background Polychlorinated biphenyls (PCBs) are food-chain contaminants that have been shown to contaminate foods worldwide. The newborn are exposed to these organochlorine compounds across the placenta and through breastfeeding. They are proven to b
Autor:
Laura Bedin Denardi, Alessandra Lorenzoni, Letícia Cruz, Sydney Hartz Alves, Natháli Schopf Pegoraro, Scheila Rezende Schaffazick, Sara S. Santos
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 116
The objective of this work was to propose coconut oil-core nanocapsules prepared from Eudragit(®) RS100, a cationic polymer, and to evaluate their potential for vaginal delivery of clotrimazole in candidiasis. Nanocapsule suspensions loaded with clo