Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Alessandra Lo Sciuto"'
Autor:
Alessandra Lo Sciuto, Francesca D'Angelo, Maria Concetta Spinnato, Pierre Simon Garcia, Shirley Genah, Cervoni Matteo, Emmanuel Séchet, Ehud Banin, Frédéric Barras, Francesco Imperi
Publikováno v:
mBio, Vol 15, Iss 11 (2024)
ABSTRACT Iron-sulfur [Fe-S] clusters are essential protein cofactors allowing bacteria to perceive environmental redox modification and to adapt to iron limitation. Escherichia coli, which served as a bacterial model, contains two [Fe-S] cluster biog
Externí odkaz:
https://doaj.org/article/36e42ead20e442fc945971507457cccf
Publikováno v:
Antibiotics, Vol 12, Iss 2, p 200 (2023)
Pseudomonas aeruginosa has the genetic potential to acquire colistin resistance through the modification of lipopolysaccharide by the addition of 4-amino-4-deoxy-L-arabinose (L-Ara4N) or phosphoethanolamine (PEtN), mediated by the arn operon or the e
Externí odkaz:
https://doaj.org/article/b3c9396be1414266a1062c65a607e7e2
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Colistin represents a last-line treatment option for infections caused by multidrug resistant Gram-negative pathogens, including Pseudomonas aeruginosa. Colistin resistance generally involves the modification of the lipid A moiety of lipopolysacchari
Externí odkaz:
https://doaj.org/article/a82e499f7e624dcfbe23d2f14ec79a3d
Autor:
Alessandra Lo Sciuto, Alessandra M. Martorana, Regina Fernández-Piñar, Carmine Mancone, Alessandra Polissi, Francesco Imperi
Publikováno v:
Virulence, Vol 9, Iss 1, Pp 1718-1733 (2018)
Lipopolysaccharide (LPS) is an essential structural component of the outer membrane (OM) of most Gram-negative bacteria. In the model organism Escherichia coli, LPS transport to the OM requires seven essential proteins (LptABCDEFG) that form a contin
Externí odkaz:
https://doaj.org/article/b90921924d594653826cf9d971568593
Autor:
Maria Concetta Spinnato, Alessandra Lo Sciuto, Jessica Mercolino, Massimiliano Lucidi, Livia Leoni, Giordano Rampioni, Paolo Visca, Francesco Imperi
Publikováno v:
Microorganisms, Vol 10, Iss 2, p 423 (2022)
DNA polymerase III (Pol III) is the replicative enzyme in bacteria. It consists of three subcomplexes, the catalytic core, the β clamp, and the clamp loader. While this complex has been thoroughly characterized in the model organism Escherichia coli
Externí odkaz:
https://doaj.org/article/074a1d916fc14737bf1b2fc13c1001ed
Autor:
Jessica Mercolino, Alessandra Lo Sciuto, Maria Concetta Spinnato, Giordano Rampioni, Francesco Imperi
Publikováno v:
Antibiotics, Vol 11, Iss 3, p 325 (2022)
To cope with stressful conditions, including antibiotic exposure, bacteria activate the SOS response, a pathway that induces error-prone DNA repair and mutagenesis mechanisms. In most bacteria, the SOS response relies on the transcriptional repressor
Externí odkaz:
https://doaj.org/article/54149e3c1ec84cf9b3394124f309547a
Autor:
Alessandra Lo Sciuto, Regina Fernández-Piñar, Lucia Bertuccini, Francesca Iosi, Fabiana Superti, Francesco Imperi
Publikováno v:
PLoS ONE, Vol 9, Iss 8, p e103784 (2014)
The Gram-negative bacterium Pseudomonas aeruginosa is one of the most dreaded pathogens in the hospital setting, and represents a prototype of multi-drug resistant "superbug" for which effective therapeutic options are very limited. The identificatio
Externí odkaz:
https://doaj.org/article/f1969373080649ef9078959f0562c19e
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 2548
The functional and physiological characterization of bacterial genes required for growth and/or cell survival is limited by the inability to generate deletion mutants lacking the specific gene of interest. This limitation can be circumvented by gener
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4f615b55f9d8d2252b9e531fd04c8316
https://pubmed.ncbi.nlm.nih.gov/36151489
https://pubmed.ncbi.nlm.nih.gov/36151489
Autor:
Regina Fernández-Piñar, Alessandra Polissi, Carmine Mancone, Francesco Imperi, Alessandra M. Martorana, Alessandra Lo Sciuto
Publikováno v:
Virulence
Virulence, Vol 9, Iss 1, Pp 1718-1733 (2018)
Virulence, Vol 9, Iss 1, Pp 1718-1733 (2018)
Lipopolysaccharide (LPS) is an essential structural component of the outer membrane (OM) of most Gram-negative bacteria. In the model organism Escherichia coli, LPS transport to the OM requires seven essential proteins (LptABCDEFG) that form a contin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c6a051bec5b390ed5662f38d030d39b
Autor:
Patrizia Morelli, Mattia Mori, Alberto Antonelli, Deborah Quaglio, Andrea Calcaterra, Maria Rosa Loffredo, Francesca Ghirga, Silvia Corradi, Carmine Mancone, Francesco Imperi, Alessandra Lo Sciuto, Maria Luisa Mangoni, Bruno Casciaro, Luca Cavinato, Fiorentina Ascenzioni, Floriana Cappiello, Roberta Stefanelli, Bruno Botta, Gian Maria Rossolini
Publikováno v:
Journal of Antimicrobial Chemotherapy
BackgroundColistin is a last-resort treatment option for many MDR Gram-negative bacteria. The covalent addition of l-aminoarabinose to the lipid A moiety of LPS is the main colistin resistance mechanism in the human pathogen Pseudomonas aeruginosa.Ob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6bc06102721a89734ae91cd2f9438469
http://hdl.handle.net/11573/1433609
http://hdl.handle.net/11573/1433609