Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Alessandra Liverziani"'
Autor:
Alexander Neil Young, Emerald Perlas, Nerea Ruiz-Blanes, Andreas Hierholzer, Nicola Pomella, Belen Martin-Martin, Alessandra Liverziani, Joanna W. Jachowicz, Thomas Giannakouros, Andrea Cerase
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Young et al. report a new mouse model for Pelger-Huet anomaly, a genetic disorder caused by mutations in the Lamin B receptor gene (Lbr) that leads to abnormal neutrophil differentiation and skeletal defects. Using CRISPR/Cas-9 editing of Lbr, which
Externí odkaz:
https://doaj.org/article/a0388b7db1f045ad87ee722dcc675a86
Autor:
Andreas Hierholzer, Corinne Chureau, Alessandra Liverziani, Nerea Blanes Ruiz, Bruce M. Cattanach, Alexander N. Young, Manish Kumar, Andrea Cerase, Phil Avner
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (28), pp.e2118182119. ⟨10.1073/pnas.2118182119⟩
Proceedings of the National Academy of Sciences of the United States of America, 2022, 119 (28), pp.e2118182119. ⟨10.1073/pnas.2118182119⟩
X chromosome inactivation (XCI) is the process of silencing one of the X chromosomes in cells of the female mammal which ensures dosage compensation between the sexes. Although theoretically random in somatic tissues, the choice of which X chromosome
Autor:
Andreas Hierholzer, Alessandra Liverziani, Thomas Giannakouros, Alexander N. Young, Belen Martin-Martin, Emerald Perlas, Nerea Ruiz-Blanes, Nicola Pomella, Joanna W. Jachowicz, Andrea Cerase
Publikováno v:
Communications Biology
Communications Biology, 4 (1)
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Communications Biology, 4 (1)
Communications Biology, Vol 4, Iss 1, Pp 1-8 (2021)
Mutations in the gene encoding Lamin B receptor (LBR), a nuclear-membrane protein with sterol reductase activity, have been linked to rare human disorders. Phenotypes range from a benign blood disorder, such as Pelger-Huet anomaly (PHA), affecting th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2bbe18c469df2993a393c4155c2726f2
http://hdl.handle.net/11568/1120997
http://hdl.handle.net/11568/1120997