Výsledky vyhledávání - "Alessandra Lanfrancotti"

Akademický článek

Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production.

Autor: Matthew J Peirce, Matthew Brook, Nicholas Morrice, Robert Snelgrove, Shajna Begum, Alessandra Lanfrancotti, Clare Notley, Tracy Hussell, Andrew P Cope, Robin Wait

Publikováno v: PLoS ONE, Vol 5, Iss 7, p e11465 (2010)

Thymocyte expressed molecule involved in selection 1 (Themis1, SwissProt accession number Q8BGW0) is the recently characterised founder member of a novel family of proteins. A second member of this family, Themis2 (Q91YX0), also known as ICB1 (Induce

Externí odkaz: https://doaj.org/article/6cf94233777e418cb30ebc33e0f21682

Zobrazit plný text záznamu

Akademický článek

Novel peptide marker corresponding to salivary protein gSG6 potentially identifies exposure to Anopheles bites.

Autor: Anne Poinsignon, Sylvie Cornelie, Montserrat Mestres-Simon, Alessandra Lanfrancotti, Marie Rossignol, Denis Boulanger, Badara Cisse, Cheikh Sokhna, Bruno Arcà, François Simondon, Franck Remoue

Publikováno v: PLoS ONE, Vol 3, Iss 6, p e2472 (2008)

In order to improve malaria control, and under the aegis of WHO recommendations, many efforts are being devoted to developing new tools for identifying geographic areas with high risk of parasite transmission. Evaluation of the human antibody respons

Externí odkaz: https://doaj.org/article/266188cc172d42f08d916dcaff3364ed

Zobrazit plný text záznamu

KAP1/TRIM28: an inhibitor of IRF5 function in inflammatory macrophages

Autor: Grigory Ryzhakov, Alessandra Lanfrancotti, Thomas Krausgruber, Irina A. Udalova, Hayley L. Eames, David Saliba

IRF5 plays a key role in the induction of pro-inflammatory cytokines, contributing to the plasticity and polarisation of macrophages to an M1 phenotype and initiation of a potent T(H)1-T(H)17 response. To better understand the means of IRF5 transcrip

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00b5ac7b2372e08be082b70e621c2d0e
https://ora.ox.ac.uk/objects/uuid:dc6be787-e4b1-4638-96c9-c8cb25d2bb74

Zobrazit plný text záznamu

FOXO3 as a new IKK-ε-controlled check-point of regulation of IFN-β expression

Autor: David Saliba, Lionel Luron, Irina A. Udalova, Alessandra Lanfrancotti, Katrina Blazek

Publikováno v: European Journal of Immunology. 42:1030-1037

Cell survival transcription factor FOXO3 has been recently implicated in moderating pro-inflammatory cytokine production by dendritic cells (DCs), but the molecular mechanisms are unclear. It was suggested that FOXO3 could antagonize NF-κB activity,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a2b6abd6e31aecfc57bc4b08e4dd52bd
https://doi.org/10.1002/eji.201141969

Zobrazit plný text záznamu

IRF5 is required for late-phase TNF secretion by human dendritic cells

Autor: Thomas Krausgruber, David Saliba, Irina A. Udalova, Grigory Ryzhakov, Alessandra Lanfrancotti, Katrina Blazek

Publikováno v: Blood; Vol 115

Spatially and temporally controlled expression of inflammatory mediators is critical for an appropriate immune response. In this study, we define the role for interferon regulatory factor 5 (IRF5) in secretion of tumor necrosis factor (TNF) by human

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a9de2943fd592896cb3b643e95fc7fc

Zobrazit plný text záznamu

Beyond the enhanceosome: cluster of novel kappa B sites downstream of the human IFN-beta gene is essential for lipopolysaccharide-induced gene activation

Autor: Alessandra Lanfrancotti, Richard R. Copley, Scott J. P. Thomson, Fui G. Goh, Thomas Krausgruber, Irina A. Udalova

Publikováno v: Blood; Vol 116

The expression of interferon-β (IFN-β) in virus-infected HeLa cells established a paradigm of multifactorial gene regulation, in which cooperative assembly of transcription factors (TFs) at the composite DNA element (enhanceosome), is central for a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55f6f57ef74f3c89502cd480a86021bd

Zobrazit plný text záznamu

Plasmodium falciparum: mRNA co-expression and protein co-localisation of two gene products upregulated in early gametocytes

Autor: Francesco Silvestrini, Lucia Bertuccini, Pietro Alano, Alessandra Lanfrancotti

Publikováno v: Experimental Parasitology. 116:497-503

Genes encoding Plasmodium falciparum proteins Pfs16 and Pfpeg3/mdv1, specifically appearing in the parasitophorous vacuole of the early gametocytes, are upregulated at the onset of sexual differentiation. Analysis of asexual development in gametocyte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e776da0ae313fea65bcb213ca53abed
https://doi.org/10.1016/j.exppara.2007.01.021

Zobrazit plný text záznamu

FOXO3 as a new IKK-ε-controlled check-point of regulation of IFN-β expression

Autor: Lionel, Luron, David, Saliba, Katrina, Blazek, Alessandra, Lanfrancotti, Irina A, Udalova

Publikováno v: European journal of immunology. 42(4)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b1eb52d66cb7e5764a1f63d524e5af08
https://pubmed.ncbi.nlm.nih.gov/22531926

Zobrazit plný text záznamu

Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production

Autor: Andrew P. Cope, Matthew Brook, Robert J. Snelgrove, Tracy Hussell, Alessandra Lanfrancotti, Clare A. Notley, Matthew J. Peirce, Robin Wait, Nicholas A. Morrice, Shajna Begum

Publikováno v: Peirce, M J, Brook, M, Morrice, N, Snelgrove, R, Begum, S, Lanfrancotti, A, Notley, C, Hussell, T, Cope, A P & Wait, R 2010, ' Themis2/ICB1 is a signaling scaffold that selectively regulates macrophage Toll-like receptor signaling and cytokine production ', PLoS ONE, vol. 5, no. 7, pp. e11465 . https://doi.org/10.1371/journal.pone.0011465
PLoS ONE
PLoS ONE, Vol 5, Iss 7, p e11465 (2010)

BACKGROUND: Thymocyte expressed molecule involved in selection 1 (Themis1, SwissProt accession number Q8BGW0) is the recently characterised founder member of a novel family of proteins. A second member of this family, Themis2 (Q91YX0), also known as

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c6bdd66b98624ca02f5a67f00d9e394b
https://hdl.handle.net/20.500.11820/e3885517-f426-44ce-9b59-d6957f56b12d

Zobrazit plný text záznamu

Regulated oligomerisation and molecular interactions of the early gametocyte protein Pfg27 in Plasmodium falciparum sexual differentiation

Autor: Saurabh Singh, Andrea Scaloni, Amit Sharma, Anna Maria Salzano, Lucia Bertuccini, Pietro Alano, Grazia Camarda, Alessandra Lanfrancotti, Anna Olivieri

Publikováno v: International Journal for Parasitology 40(6) (2010): 663–673. doi:10.1016/j.ijpara.2009.11.006
info:cnr-pdr/source/autori:Camarda G, Bertuccini L, Singh SK, Salzano AM, Lanfrancotti A, Olivieri A, Scaloni A, Sharma A, Alano P./titolo:Regulated oligomerisation and molecular interactions of the early gametocyte protein Pfg27 in Plasmodium falciparum sexual differentiation./doi:10.1016%2Fj.ijpara.2009.11.006/rivista:International Journal for Parasitology/anno:2010/pagina_da:663/pagina_a:673/intervallo_pagine:663–673/volume:40(6)

Gametocytes of the protozoan Plasmodium falciparum ensure malaria parasite transmission from humans to the insect vectors. In their development, they produce the abundant specific protein Pfg27, the function and in vivo molecular interactions of whic

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77cbf0aeed1c9413598ab25dd3b41756
http://www.cnr.it/prodotto/i/51564

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání