Výsledky vyhledávání - "Alessandra Jordano Conforte"

Akademický článek

Data-Driven Modeling of Breast Cancer Tumors Using Boolean Networks

Autor: Domenico Sgariglia, Alessandra Jordano Conforte, Carlos Eduardo Pedreira, Luis Alfredo Vidal de Carvalho, Flavia Raquel Gonçalves Carneiro, Nicolas Carels, Fabricio Alves Barbosa da Silva

Publikováno v: Frontiers in Big Data, Vol 4 (2021)

Cancer is a genomic disease involving various intertwined pathways with complex cross-communication links. Conceptually, this complex interconnected system forms a network, which allows one to model the dynamic behavior of the elements that character

Externí odkaz: https://doaj.org/article/6bce7ec3a11e4b8da67c20dce99afccf

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Akademický článek

Galaxy and MEAN Stack to Create a User-Friendly Workflow for the Rational Optimization of Cancer Chemotherapy

Autor: Jorge Guerra Pires, Gilberto Ferreira da Silva, Thomas Weyssow, Alessandra Jordano Conforte, Dante Pagnoncelli, Fabricio Alves Barbosa da Silva, Nicolas Carels

Publikováno v: Frontiers in Genetics, Vol 12 (2021)

One aspect of personalized medicine is aiming at identifying specific targets for therapy considering the gene expression profile of each patient individually. The real-world implementation of this approach is better achieved by user-friendly bioinfo

Externí odkaz: https://doaj.org/article/5f53ad0f5e764a508b596b11d9b543d0

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Akademický článek

Modeling Basins of Attraction for Breast Cancer Using Hopfield Networks

Autor: Alessandra Jordano Conforte, Leon Alves, Flávio Codeço Coelho, Nicolas Carels, Fabrício Alves Barbosa da Silva

Publikováno v: Frontiers in Genetics, Vol 11 (2020)

Cancer is a genetic disease for which traditional treatments cause harmful side effects. After two decades of genomics technological breakthroughs, personalized medicine is being used to improve treatment outcomes and mitigate side effects. In mathem

Externí odkaz: https://doaj.org/article/715f2fbb810a442db04064f3e01fd5c4

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Akademický článek

Isolation and characterization of a promoter responsive to salt, osmotic and dehydration stresses in soybean

Autor: Alessandra Jordano Conforte, Fábia Guimarães-Dias, Anna Cristina Neves-Borges, Marta Bencke-Malato, Durvalina Felix-Whipps, Márcio Alves-Ferreira

Publikováno v: Genetics and Molecular Biology, Vol 40, Iss 1 suppl 1, Pp 226-237 (2017)

Abstract Drought stress is the main limiting factor of soybean yield. Currently, genetic engineering has been one important tool in the development of drought-tolerant cultivars. A widely used strategy is the fusion of genes that confer tolerance und

Externí odkaz: https://doaj.org/article/c9157f6606984689a58d6d6dafe812a0

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Cellular Regulatory Network Modeling Applied to Breast Cancer

Autor: Nicolas Carels, Luiz Henrique Oliveira Ferreira, Fabricio Alves Barbosa da Silva, Alessandra Jordano Conforte, Maria Clicia Stelling de Castro

Publikováno v: Networks in Systems Biology ISBN: 9783030518615

Cells in an organism interact with each other and with the environment through a complex set of signals, which triggers responses and activates cellular regulation mechanisms. Models obtained by computational mathematics for cellular signaling dynami

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::430ba9d5136e16fc404106b37dac7566
https://doi.org/10.1007/978-3-030-51862-2_13

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Challenges for the Optimization of Drug Therapy in the Treatment of Cancer

Autor: Fabricio Alves Barbosa da Silva, Alessandra Jordano Conforte, Carlyle Ribeiro Lima, Nicolas Carels

Publikováno v: Networks in Systems Biology ISBN: 9783030518615

Personalized medicine aims at identifying specific targets for treatment considering the gene expression profile of each patient individually. We discuss the challenges for personalized oncology to take off and present an approach based on hub inhibi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a8e13d5c048a1be1bafe5232ae2f73ab
https://doi.org/10.1007/978-3-030-51862-2_8

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Single Cell Transcriptomics Revealed Molecular Alterations in AML Cell Clusters Relevant to Refractory Disease at Relapse

Autor: Philippe Krebs, Sarah Ennis, Eva Szegezdi, Sukhraj Pal Singh Dhami, Alessandra Jordano Conforte, Michael O'Dwyer

Publikováno v: Blood. 138:3316-3316

Introduction: Drug resistance at relapse is a major cause of mortality in AML. Previous genomic profiling of AML patient samples revealed that in many cases the mutational profile did not change between diagnosis and relapse (Parkin et al., Blood, 20

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ce9adc8556d5203626a9912fb5f9bfa4
https://doi.org/10.1182/blood-2021-153910

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Isolation and characterization of a promoter responsive to salt, osmotic and dehydration stresses in soybean

Autor: Marcio Alves-Ferreira, Marta Bencke-Malato, Durvalina Felix-Whipps, Anna Cristina Neves-Borges, Fábia Guimarães-Dias, Alessandra Jordano Conforte

Publikováno v: Genetics and Molecular Biology v.40 n.1 suppl.1 2017
Genetics and Molecular Biology
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Volume: 40, Issue: 1 Supplement 1, Pages: 226-237, Published: 27 MAR 2017
Genetics and Molecular Biology, Vol 40, Iss 1 suppl 1, Pp 226-237 (2017)

Drought stress is the main limiting factor of soybean yield. Currently, genetic engineering has been one important tool in the development of drought-tolerant cultivars. A widely used strategy is the fusion of genes that confer tolerance under the co

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb95f0f126d013b00a86aa09726c0d76
https://doi.org/10.1590/1678-4685-gmb-2016-0052

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