Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Alessandra Hillis"'
Autor:
Carlos Fernandez-del Castillo, Teppei Yamada, Linda T. Nieman, Chittampalli Yashaswini, Shyamala Maheswaran, Rebecca L. Porter, Vishal Thapar, Daniel A. Haber, Jeffrey A. Drebin, Gabriel Golczer, David P. Ryan, Michael S. Lawrence, David T. Ting, Tomohiro Kurokawa, Cristina R. Ferrone, Kevin D. Vo, Peter J. O'Dwyer, Alessandra Hillis, Annamaria Szabolcs, Anupriya S. Kulkarni, Abhijit Chougule, Theodore S. Hong, Robert Morris, Andrew S. Liss, Hongshan Guo, Neelima K.C. Magnus, Vikram Deshpande, Azfar Neyaz, Eric Tai, Matteo Ligorio
Publikováno v:
Proceedings of the National Academy of Sciences. 116:26835-26845
Transcriptional profiling has defined pancreatic ductal adenocarcinoma (PDAC) into distinct subtypes with the majority being classical epithelial (E) or quasi-mesenchymal (QM). Despite clear differences in clinical behavior, growing evidence indicate
Autor:
Carlos Fernandez-del Castillo, Robert Morris, Rebecca L. Porter, Shyamala Maheswaran, Vikram Deshpande, Linda T. Nieman, Matteo Ligorio, Anupriya S. Kulkarni, Cristina R. Ferrone, Daniel A. Haber, Neelima K.C. Magnus, Vishal Thapar, Andrew S. Liss, Abhijit Chougule, Gabriel Golczer, Theodore S. Hong, Kevin D. Vo, Eric Tai, Chittampalli Yashaswini, David T. Ting, Annamaria Szabolcs, Alessandra Hillis, Jeffrey A. Drebin, Peter J. O'Dwyer, Hongshan Guo, David P. Ryan, Michael S. Lawrence, Tomohiro Kurokawa, Azfar Neyaz, Teppei Yamada
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America
Significance PDAC epithelial (E) and quasi-mesenchymal (QM) subtypes can be modulated by different therapies demonstrating the plasticity of PDAC cells that contributes to the heterogeneity of PDAC tumors and their intrinsic resistance to a broad spe