HIPK2 Controls Cytokinesis and Prevents Tetraploidization by Phosphorylating Histone H2B at the Midbody

Autor: M. Eugenia Schininà, Silvia Soddu, Andrea Prodosmo, Francesco Trapasso, Cinzia Rinaldo, Laura Ciuffini, Donatella D’Eliseo, Alessandra Gradi, Enrico Cundari, Armando Bartolazzi, Alfredo Fusco, Francesca Siepi, Giovanna Maria Pierantoni, Alice Moncada, Alessandra Giorgi, Giulia Guarguaglini

Publikováno v: Molecular cell (2012). doi:10.1016/j.molcel.2012.04.029.
info:cnr-pdr/source/autori:Rinaldo C, Moncada A, Gradi A, Ciuffini L, D'Eliseo D, Siepi F, Prodosmo A, Giorgi A, Pierantoni GM, Trapasso F, Guarguaglini G, Bartolazzi A, Cundari E, Schininà ME, Fusco A, Soddu S./titolo:HIPK2 controls cytokinesis and prevents tetraploidization by phosphorylating histone H2B at the midbody./doi:10.1016%2Fj.molcel.2012.04.029./rivista:Molecular cell/anno:2012/pagina_da:/pagina_a:/intervallo_pagine:/volume

Orthodontics is a branch of dentistry that aims at the resolution of dental malocclusions. The specialist carries out the treatment using intraoral or extraoral orthodontic appliances that require forces of a given load level to obtain a tooth moveme

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f3fda49cdca11c01a143fc877e2f05a
https://doi.org/10.1016/j.molcel.2012.04.029

The human steroidogenic acute regulatory (StAR) gene is expressed in the urogenital system and encodes a mitochondrial polypeptide

Autor: Alessandra Gradi, Heidi M. McBride, Lee Lee Chu, Richard Tang-Wai, Gordon C. Shore, Jerry Pelletier

Publikováno v: Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 1258:228-233

The first enzymatic step in the biosynthesis of steroid hormones occurs in the mitochondrial inner membrane and is dependent on the mobilization of cholesterol from cellular stores. We report on the isolation of a human cDNA which encodes a mitochond

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80fdf2a2a8959fdff2f7edc8a1f80912
https://doi.org/10.1016/0005-2760(95)00140-8

Human Rhinovirus 2A Proteinase Cleavage Sites in Eukaryotic Initiation Factors (eIF) 4GI and eIF4GII Are Different

Autor: Shigenobu Morino, Wolfgang Sommergruber, Tim Skern, Yuri V. Svitkin, Alessandra Gradi, Hiroaki Imataka, Nahum Sonenberg

Several picornaviruses shut down host cellular protein synthesis by proteolytic cleavage of the eukaryotic initiation factor (eIF) 4GI and eIF4GII isoforms. Viral RNA translation is maintained by a cap-independent mechanism. Here, we identify the hum

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d546c601598a0db819ac75aaf4bfd8a
https://europepmc.org/articles/PMC152112/

Poliovirus 2A protease induces apoptotic cell death

Autor: Zehava Grosmann, Dan Goldstaub, Nahum Sonenberg, Yaron Nophar, Sylvie Luria, Alessandra Gradi, Zippi Bercovitch, Chaim Kahana

Publikováno v: Molecular and cellular biology. 20(4)

A cell line was generated that expresses the poliovirus 2A protease in an inducible manner. Tightly controlled expression was achieved by utilizing the muristerone A-regulated expression system. Upon induction, cleavage of the eukaryotic translation

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c0f578409bd44372dba765b8a65284b
https://pubmed.ncbi.nlm.nih.gov/10648613

A Novel Functional Human Eukaryotic Translation Initiation Factor 4G

Autor: Nahum Sonenberg, Alessandra Gradi, Brian Raught, Hiroaki Imataka, Eran Rom, Shigenobu Morino, Yuri V. Svitkin

Mammalian eukaryotic translation initiation factor 4F (eIF4F) is a cap-binding protein complex consisting of three subunits: eIF4E, eIF4A, and eIF4G. In yeast and plants, two related eIF4G species are encoded by two different genes. To date, however,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03718620ea7f30c7793c6710a434d40
https://europepmc.org/articles/PMC121501/