Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Alessandra Failli"'
Autor:
Alessandra Failli, Annalisa Legitimo, Francesca Migheli, Fabio Coppedè, John C. Mathers, Roberto Spisni, Paolo Miccoli, Lucia Migliore, Rita Consolini
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 1, Pp 44-57 (2013)
The aim of this work was to assess the impact on measurements of methylation of a panel of four cancer gene promoters of purifying tumor cells from colorectal tissue samples using the epithelial cell adhesion molecule (EpCAM)-immunomagnetic cell enri
Externí odkaz:
https://doaj.org/article/6f29f6a6d3d54cb987f6810fab9a64e9
Autor:
Rita Consolini, Paolo Miccoli, Alessandra Failli, Paola Ferrari, Andrea Nicolini, Roberto Spisni, Annalisa Legitimo, Giulia Orsini
Publikováno v:
International Journal of Molecular Sciences, Vol 14, Iss 11, Pp 22022-22041 (2013)
Colorectal cancer (CRC) is the second-leading cause of cancer-related deaths in Western countries. Today, the role of the host’s immune system in controlling the progression and spread of solid tumors is broadly established. Tumor immunosurveillanc
Externí odkaz:
https://doaj.org/article/c0ace0131ea847d39fae4737ed8226f6
Autor:
Francesca Migheli, Andrea Stoccoro, Fabio Coppedè, Wan Adnan Wan Omar, Alessandra Failli, Rita Consolini, Massimo Seccia, Roberto Spisni, Paolo Miccoli, John C Mathers, Lucia Migliore
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e52501 (2013)
There is increasing interest in the development of cost-effective techniques for the quantification of DNA methylation biomarkers. We analyzed 90 samples of surgically resected colorectal cancer tissues for APC and CDKN2A promoter methylation using m
Externí odkaz:
https://doaj.org/article/5c4a81471e914b33a87f1a27b87743bb
Publikováno v:
Human Vaccines & Immunotherapeutics
Colorectal cancer (CRC) results from the accumulation of both genetic and epigenetic alterations of the genome. However, also the formation of an inflammatory milieu plays a pivotal role in tumor development and progression. Dendritic cells (DCs) pla
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1409fc9dfaf019a1219472caf0c6722
https://doi.org/10.4161/hv.29857
https://doi.org/10.4161/hv.29857
Autor:
Francesca Migheli, Gabriella Fontanini, Angela Lopomo, Massimo Seccia, Adele Servadio, Annalisa Legitimo, Elisa Sensi, Rita Consolini, Massimo Chiarugi, Fabio Coppedè, Giuseppe Zocco, Lucia Migliore, Alessandra Failli, Roberto Spisni
Publikováno v:
Epigenetics. 9:621-633
We evaluated the promoter methylation levels of the APC, MGMT, hMLH1, RASSF1A and CDKN2A genes in 107 colorectal cancer (CRC) samples and 80 healthy adjacent tissues. We searched for correlation with both physical and pathological features, polymorph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9c500e5de034aead21fa57ab4d0a97d
https://doi.org/10.4161/epi.27956
https://doi.org/10.4161/epi.27956
Autor:
John C. Mathers, Lucia Migliore, Paolo Miccoli, Alessandra Failli, Rita Consolini, Annalisa Legitimo, Roberto Spisni, Francesca Migheli, Fabio Coppedè
Publikováno v:
International Journal of Molecular Sciences, Vol 15, Iss 1, Pp 44-57 (2013)
International Journal of Molecular Sciences
Volume 15
Issue 1
Pages 44-57
International Journal of Molecular Sciences
Volume 15
Issue 1
Pages 44-57
The aim of this work was to assess the impact on measurements of methylation of a panel of four cancer gene promoters of purifying tumor cells from colorectal tissue samples using the epithelial cell adhesion molecule (EpCAM)-immunomagnetic cell enri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6179232215e8eec9765727e5b8e3a22f
http://www.mdpi.com/1422-0067/15/1/44
http://www.mdpi.com/1422-0067/15/1/44
Autor:
G Crimaldi, Paolo Miccoli, Maura Castagna, Alessandra Failli, Annalisa Legitimo, Rita Consolini, Roberto Spisni, Antonella Romanini
Publikováno v:
Tumori Journal. 95:343-347
Background Because colorectal cancer is a significant cause of morbidity and mortality in the Western population, knowledge of the molecular and biological alterations associated with its development is important. Since primary human colon cancer cul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a3e6ccfb81bd7e45dc46f2f5340122
https://doi.org/10.1177/030089160909500312
https://doi.org/10.1177/030089160909500312
Autor:
Alessandra Failli, W. Bencivelli, Franco Mosca, F. Scatena, Rita Consolini, Annalisa Legitimo, S. Fabiano
Publikováno v:
Clinical and Experimental Immunology. 148:564-572
Summary Extracorporeal photopheresis (ECP) has been considered an efficient dendritic cell (DC) therapy, used for treating both T cell malignancy, as well as T cell-mediated diseases. During the ECP procedure leucocytes are exposed to photoactivable
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9d85f7ae43a4e1e00c6b5d658f3b981
https://doi.org/10.1111/j.1365-2249.2007.03372.x
https://doi.org/10.1111/j.1365-2249.2007.03372.x
Autor:
G Orsini, Paolo Miccoli, Andrea Nicolini, Annalisa Legitimo, Rita Consolini, Roberto Spisni, Paola Ferrari, Alessandra Failli
Colorectal cancer is a malignancy with poor prognosis that might be associated with defective immune function. The aim of the present study was to investigate circulating dendritic cells in colorectal cancer patients, in order to contribute to elucid
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7d68b447e20f6b95f3af9d5a1fbfd3ea
http://hdl.handle.net/11568/255161
http://hdl.handle.net/11568/255161
Publikováno v:
Human Vaccines & Immunotherapeutics
Zoledronic acid has shown indirect anticancer effects on angiogenesis, the tumor microenvironment and immune responses. Its immunological action is exerted, at least in part, via its modulating properties. The aim of this study was to investigate the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b958b9c136434207f4ca0ecab4a51fda
http://hdl.handle.net/11568/713063
http://hdl.handle.net/11568/713063