Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alessandra Di Cintio"'
Publikováno v:
Recent Patents on Anti-Cancer Drug Discovery. 5:1-13
p53 Tumor suppressor gene encodes for a critical cellular protein that regulate the integrity of the cell and can induce cell cycle arrest and/or apoptosis upon cellular stresses of several origins, including chemotherapeutics. Loss of p53 function o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e0cbc72388472911ec5fbf8a61d7f15
https://doi.org/10.2174/157489210789702172
https://doi.org/10.2174/157489210789702172
Autor:
Ferdinando Fiorino, Cristina Nencini, Francesca De Angelis, Elisa Perissutti, Vincenzo Santagada, Giuseppina Maria Incisivo, Francesco Frecentese, Alessandra Di Cintio, Alfredo Budillon, Elena Di Gennaro, Elisa Magli, Antonella Esposito, Beatrice Severino, Paola Massarelli, Giuseppe Caliendo
Publikováno v:
European journal of medicinal chemistry. 46(6)
Serotonin (5-hydroxytryptamine, 5-HT) is one of the most important neuromediator involved in numerous physiological and pathophysiological processes. In addition it is well established that 5-HT acts as a growth factor on several types of non-tumoral
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::97af706df133801f33bb4032510f70b4
https://pubmed.ncbi.nlm.nih.gov/21440338
https://pubmed.ncbi.nlm.nih.gov/21440338
Autor:
Alessandra Di Cintio, Geny Piro, Alfredo Budillon, Elena Di Gennaro, Francesca Bruzzese, Maria I. Chianese
Publikováno v:
Cancer Research. 71:3519-3519
Capecitabine is a pro-drug which was designed to take advantage of the increased levels of thymidine phosphorylase (TP), a key enzyme for its conversion to 5-florouracil (5-FU), observed in tumours as opposed to normal tissues, potentially allowing f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1729dfda79ae8f08c556a2d1415f766e
https://doi.org/10.1158/1538-7445.am2011-3519
https://doi.org/10.1158/1538-7445.am2011-3519
Autor:
Antonio Luciano, Geny Piro, Alfredo Budillon, Francesca Bruzzese, Alessandra Di Cintio, Claudio Arra, Maria I. Chianese, Tania Moccia, Elena Di Gennaro
Publikováno v:
Cancer Research. 70:5442-5442
The oral fluoropyrimidine capecitabine is converted to the active compound 5-florouracil (5-FU) in several steps, the last of which is the conversion of 5′-deoxy-5-fluorouridine (5′DFUR) to 5-FU by thymidine phosphorylase (TP). Capecitabine was d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::da5838c94644684316f2c6ef7887e951
https://doi.org/10.1158/1538-7445.am10-5442
https://doi.org/10.1158/1538-7445.am10-5442