Zobrazeno 1 - 9 of 9 pro vyhledávání: '"Alessandra Cadeddu"'
1
5-Alkyl-2-alkylamino-6-(2,6-difluorophenylalkyl)-3,4-dihydropyrimidin-4(3H)-ones, a new series of potent, broad-spectrum non-nucleoside reverse transcriptase inhibitors belonging to the DABO family
Autor: Gianluca Sbardella, Silvio Massa, Paolo La Colla, Giovanni Maga, Flavia Marturana, Antonello Mai, Massimo Mura, Chiara Musiu, Rino Ragno, Marino Artico, Alessandra Cadeddu
Publikováno v: Bioorganic & Medicinal Chemistry. 13:2065-2077
2-Alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)-ones (F(2)-NH-DABOs) 4, 5 belonging to the dihydro-alkoxy-benzyl-oxopyrimidine (DABO) family and bearing different alkyl- and arylamino side chains at the C(2)-position o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79bf789573860b68f6083d57bcd25c8f
https://doi.org/10.1016/j.bmc.2005.01.005
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2
Isolation ofJuniperus phoeniceaVolatiles by Supercritical Carbon Dioxide Extraction and Bioactivity Assays
Autor: Alessandra Cadeddu, Silvia Porcedda, Valeria Mascia, Laura Vargiu, Roberta Loddo, Alessandra Caredda, Bruno Marongiu, Alessandra Piras
Publikováno v: Journal of Essential Oil Research. 16:256-261
By means of a supercritical fluid extractor, extract of Juniperus phoenicea L. was obtained in a single extraction stage. The yield was 0.2% by mass. The operative conditions were: extractor, pressure, P = 90 bar and temperature, T = 50°C; first sep
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d0518abacfd7709b4d7ddc3420beb85b
https://doi.org/10.1080/10412905.2004.9698715
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3
Computer-Aided Design, Synthesis, and Anti-HIV-1 Activity in Vitro of 2-Alkylamino-6-[1-(2,6-difluorophenyl)alkyl]-3,4-dihydro-5-alkylpyrimidin-4(3H)- ones as Novel Potent Non-Nucleoside Reverse Transcriptase Inhibitors, Also Active Against the Y181C Variant
Autor: Silvio Massa, and Alessandra Cadeddu, M. Mura, Antonello Mai, Flavia Marturana, Rino Ragno, Paolo La Colla, Marino Artico, Gianluca Sbardella, Musiu C
Publikováno v: Journal of Medicinal Chemistry. 47:928-934
Dihydro-alkoxy-benzyl-oxopyrimidines (DABOs) are a family of potent NNRTIs developed in the past decade. Attempts to improve their potency and selectivity led to thio-DABOs (S-DABOs), DATNOs, and difluoro-thio-DABOs (F(2)-S-DABOs). More recently, we
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4f44f4ba0c8de180bf1881faeab0eb16
https://doi.org/10.1021/jm0309856
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4
Synthesis and antiviral evaluation of 4-fluoropyrazole-3-carboxamide nucleoside derivatives
Autor: Jean-Pierre Sommadossi, Alessandra Cadeddu, Gilles Gosselin, Maura Fanti, Nadia Boscu, Fabiola Bassetti, Anna Giulia Loi, David Dukhan, Richard Storer, Frederic Leroy, Michel Liuzzi, Dominique Chaves
Publikováno v: Nucleic acids symposium series (2004). (52)
A series of novel 4-fluoro-1H-pyrazole-3-carboxamide nucleoside analogues were synthesized and evaluated as potential inhibitors of RNA virus replication, including hepatitis C virus (HCV).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7118bac5fca3c807a9346cc40359a84b
https://pubmed.ncbi.nlm.nih.gov/18776531
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5
Synthesis and antiviral evaluation of 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives
Autor: Fabiola Bassetti, Dominique Chaves, David Dukhan, Frederic Leroy, Alessandra Cadeddu, Michel Liuzzi, Nadia Boscu, Richard Storer, Jean-Pierre Sommadossi, Anna Giulia Loi, Gilles Gosselin, Maura Fanti
Publikováno v: Nucleic acids symposium series (2004). (52)
Three 7-fluoro-7-deaza-2-aminopurine nucleoside derivatives were synthesized and evaluated as potential inhibitors of RNA virus replication, including hepatitis C virus (HCV).
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35579eee9a3adcd3eb79b1e9c1133dca
https://pubmed.ncbi.nlm.nih.gov/18776520
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7
Synthesis and study of 9-deazaguanosine derivatives as potential inhibitors of RNA virus replication
Autor: Fabiola Bassetti, Claire Pierra, Richard Storer, Anna Giulia Loi, Marie Hamann, Gilles Gosselin, Maura Fanti, Nadia Boscu, Jean-Pierre Sommadossi, Michel Liuzzi, Alessandra Cadeddu
Publikováno v: Nucleic Acids Symposium Series. 52:603-604
9-Deazaguanosine and the alpha and beta anomers of its 2'-C-methyl counter part, have been synthesized and evaluated against a broad range of RNA viruses, including hepatitis C virus.
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adacb41ba8dbc02a29fb47ba2e590b93
https://doi.org/10.1093/nass/nrn305
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9
Hindered nucleoside analogs as antiflaviviridae agents
Autor: Roberta Loddo, M. Mura, Marco Ferrone, M. A. Piano, Angela Angusti, Nicola Solaroli, F. Nalin, Barbara Poddesu, Augusto C. Veronese, Elisa Durini, Alessandra Cadeddu, Sabrina Pricl, P. La Colla, Silvia Vertuani, Stefano Manfredini
Publikováno v: Scopus-Elsevier
Università degli studi di Ferrara-IRIS
Flaviviridae are an important family of viruses, responsible for widely spread diseases such as dengue and West Nile fever and hepatitis C. Despite the severity of the related diseases, no effective antiviral treatments for infection are available. F
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1842bcd0b16a962ddbfd747741f120d1
http://www.scopus.com/inward/record.url?eid=2-s2.0-3242681461&partnerID=MN8TOARS
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