Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Alessandra Boe"'
Autor:
Giorgia Castellani, Mariachiara Buccarelli, Quintino Giorgio D’Alessandris, Ramona Ilari, Andrea Cappannini, Francesca Pedini, Alessandra Boe, Valentina Lulli, Isabella Parolini, Stefano Giannetti, Mauro Biffoni, Vincenzo Zappavigna, Giovanna Marziali, Roberto Pallini, Lucia Ricci-Vitiani
Publikováno v:
Cancer Cell International, Vol 24, Iss 1, Pp 1-20 (2024)
Abstract Background Glioblastoma (GBM) is the most lethal primary brain tumor in adult, characterized by highly aggressive and infiltrative growth. The current therapeutic management of GBM includes surgical resection followed by ionizing radiations
Externí odkaz:
https://doaj.org/article/8e3913e82bb74f93b3154024337733d7
Autor:
Maria Laura De Angelis, Federica Francescangeli, Chiara Nicolazzo, Michele Signore, Alessandro Giuliani, Lidia Colace, Alessandra Boe, Valentina Magri, Marta Baiocchi, Antonio Ciardi, Francesco Scarola, Massimo Spada, Filippo La Torre, Paola Gazzaniga, Mauro Biffoni, Ruggero De Maria, Ann Zeuner
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 41, Iss 1, Pp 1-15 (2022)
Abstract Background Circulating tumor cells (CTCs) are responsible for the metastatic dissemination of colorectal cancer (CRC) to the liver, lungs and lymph nodes. CTCs rarity and heterogeneity strongly limit the elucidation of their biological featu
Externí odkaz:
https://doaj.org/article/d558e197a70349ccafa097cd3b68c930
Autor:
Mariachiara Buccarelli, Quintino Giorgio D’Alessandris, Paola Matarrese, Cristiana Mollinari, Michele Signore, Andrea Cappannini, Maurizio Martini, Pierluigi D’Aliberti, Gabriele De Luca, Francesca Pedini, Alessandra Boe, Mauro Biffoni, Roberto Pallini, Lucia Ricci-Vitiani
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 40, Iss 1, Pp 1-17 (2021)
Abstract Background Glioblastoma (GBM) is the most common and aggressive primary malignant brain tumor in adults, characterized by a poor prognosis mainly due to recurrence and therapeutic resistance. It has been widely demonstrated that glioblastoma
Externí odkaz:
https://doaj.org/article/62c7ec53f0a44978a597b85b63f2a6b7
Autor:
Giorgia Castellani, Mariachiara Buccarelli, Valentina Lulli, Ramona Ilari, Gabriele De Luca, Francesca Pedini, Alessandra Boe, Nadia Felli, Mauro Biffoni, Emanuela Pilozzi, Giovanna Marziali, Lucia Ricci-Vitiani
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
MiR-378a-3p plays a critical role in carcinogenesis acting as a tumor suppressor, promoting apoptosis and cell cycle arrest and reducing invasion and drug resistance in several human cancers, including colorectal cancer (CRC), where its expression is
Externí odkaz:
https://doaj.org/article/131d94c91ae34040a5507722e0c7fbef
Autor:
Federica Francescangeli, Maria Laura De Angelis, Rachele Rossi, Giovanni Sette, Adriana Eramo, Alessandra Boe, Ombretta Guardiola, Tao Tang, Shi-Cang Yu, Gabriella Minchiotti, Ann Zeuner
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Chemotherapy is the mainstay for the treatment of non-small cell lung cancer (NSCLC). However, NSCLC cells are either intrinsically chemoresistant or rapidly develop therapy resistance. Cancer stem cells (CSCs) are widely recognized as the cell popul
Externí odkaz:
https://doaj.org/article/7c7e41a2a4654a0b8288753f8239a4c2
Autor:
Federica Francescangeli, Paola Contavalli, Maria Laura De Angelis, Silvia Careccia, Michele Signore, Tobias Longin Haas, Federico Salaris, Marta Baiocchi, Alessandra Boe, Alessandro Giuliani, Olga Tcheremenskaia, Alfredo Pagliuca, Ombretta Guardiola, Gabriella Minchiotti, Lidia Colace, Antonio Ciardi, Vito D’Andrea, Filippo La Torre, JanPaul Medema, Ruggero De Maria, Ann Zeuner
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 39, Iss 1, Pp 1-17 (2020)
Abstract Background Quiescent/slow cycling cells have been identified in several tumors and correlated with therapy resistance. However, the features of chemoresistant populations and the molecular factors linking quiescence to chemoresistance are la
Externí odkaz:
https://doaj.org/article/00bd58b74b414a74be068d6e8d3ce09f
Autor:
Francesca Pedini, Gabriele De Luca, Federica Felicetti, Rossella Puglisi, Alessandra Boe, Maria Beatrice Arasi, Federica Fratini, Gianfranco Mattia, Massimo Spada, Simona Caporali, Mauro Biffoni, Alessandro Giuliani, Alessandra Carè, Nadia Felli
Publikováno v:
Molecular Oncology, Vol 13, Iss 9, Pp 1836-1854 (2019)
Emerging data support the rationale of combined therapies in advanced melanoma. Specifically, the combined use of drugs with different mechanisms of action can reduce the probability of selecting resistant clones. To identify agents active against me
Externí odkaz:
https://doaj.org/article/b92616b37ad54c52865b78ab9cf56fdd
Autor:
Michela Relucenti, Federica Francescangeli, Maria Laura De Angelis, Vito D’Andrea, Selenia Miglietta, Emanuela Pilozzi, Xiaobo Li, Alessandra Boe, Rui Chen, Ann Zeuner, Giuseppe Familiari
Publikováno v:
Biology, Vol 10, Iss 9, p 929 (2021)
Spheroids from primary colorectal cancer cells and their mice xenografts have emerged as useful preclinical models for cancer research as they replicate tumor features more faithfully as compared to cell lines. While 3D models provide a reliable syst
Externí odkaz:
https://doaj.org/article/c286f53c2cbd4b85925b0f5168224d97
Autor:
Valentina Lulli, Mariachiara Buccarelli, Ramona Ilari, Giorgia Castellani, Chiara De Dominicis, Alessandra Di Giamberardino, Quintino Giorgio D′Alessandris, Stefano Giannetti, Maurizio Martini, Vittorio Stumpo, Alessandra Boe, Gabriele De Luca, Mauro Biffoni, Giovanna Marziali, Roberto Pallini, Lucia Ricci-Vitiani
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 10, p 3610 (2020)
Glioblastoma (GBM) is the most aggressive and prevalent form of a human brain tumor in adults. Several data have demonstrated the implication of microRNAs (miRNAs) in tumorigenicity of GBM stem-like cells (GSCs). The regulatory functions of miRNAs in
Externí odkaz:
https://doaj.org/article/b1c81b32069846248df1a5ec8e156a53
Autor:
Lidia Villanova, Chiara Barbini, Cristina Piccolo, Alessandra Boe, Ruggero De Maria, Micol Eleonora Fiori
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 7, p 2423 (2020)
MicroRNAs are tiny but powerful regulators of gene expression at the post-transcriptional level. Aberrant expression of oncogenic and tumor-suppressor microRNAs has been recognized as a common feature of human cancers. Colorectal cancer represents a
Externí odkaz:
https://doaj.org/article/3af0f662b6c842f88fdff981759d838e