Výsledky vyhledávání - "Alessandra Bergonzi"

Preparation of Amorphous Solid Dispersions by Cryomilling: Chemical and Physical Concerns Related to Active Pharmaceutical Ingredients and Carriers

Autor: Robin Koekoekx, Emiel Michiels, Guy Van den Mooter, Timothy Pas, Bjorn Vergauwen, Joost Schymkowitz, Christian Clasen, Frederic Rousseau, Alessandra Bergonzi

Publikováno v: Molecular pharmaceutics. 17(3)

In this work, a chemical (and physical) evaluation of cryogenic milling to manufacture amorphous solid dispersions (ASDs) is provided to support novel mechanistic insights in the cryomilling process. Cryogenic milling devices are considered as reacto

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04daaca255c6a51b9298f49eb3b584fe
https://pubmed.ncbi.nlm.nih.gov/31961692

Zobrazit plný text záznamu

Drug-carrier binding and enzymatic carrier digestion in amorphous solid dispersions containing proteins as carrier

Autor: Guy Van den Mooter, Alessandra Bergonzi, Eveline Lescrinier, Bjorn Vergauwen, Timothy Pas

Publikováno v: International journal of pharmaceutics. 563

In order to further explain the ability of gelatin 50PS and bovine serum albumin (BSA) to generate supersaturation of a series of poorly soluble drugs (carbamazepine, cinnarizine, diazepam, itraconazole, nifedipine, indomethacin, darunavir (ethanolat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e5c2ab4b24079333af9408a2bfc35f4
https://pubmed.ncbi.nlm.nih.gov/30935916

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání