Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Alessandra Nurisso"'
Autor:
Lucía Pérez-Regidor, Joan Guzmán-Caldentey, Nils Oberhauser, Carmen Punzón, Balázs Balogh, José R. Pedro, Eva Falomir, Alessandra Nurisso, Péter Mátyus, J. Carlos Menéndez, Belén de Andrés, Manuel Fresno, Sonsoles Martín-Santamaría
Publikováno v:
Biomedicines, Vol 10, Iss 9, p 2326 (2022)
The innate immunity toll-like receptor 4 (TLR4) system is a receptor of paramount importance as a therapeutic target. Virtual screening following a “computer-aided drug repurposing” approach was applied to the discovery of novel TLR4 modulators w
Externí odkaz:
https://doaj.org/article/0f1178007a05470795f7fc9e89be0e3d
Autor:
Mohamed D. M. Traoré, Vincent Zwick, Claudia A. Simões-Pires, Alessandra Nurisso, Mark Issa, Muriel Cuendet, Marjorie Maynadier, Sharon Wein, Henri Vial, Helene Jamet, Yung-Sing Wong
Publikováno v:
ACS Omega, Vol 2, Iss 4, Pp 1550-1562 (2017)
Externí odkaz:
https://doaj.org/article/ee61c804c38643ec997c1930494af5e4
Autor:
Laura Goracci, Alessandra Nurisso, Emile Roussel, Basile Pérès, Vincent Chaptal, Pierre Falson, Christelle Marminon, Joachim Jose, Marc Le Borgne, Ahcène Boumendjel
Publikováno v:
European Journal of Medicinal Chemistry. 248:115070
Autor:
Lionel Sacconnay, Melissa Angleviel, Giuseppe Marco Randazzo, Marcos Marçal Ferreira Queiroz, Emerson Ferreira Queiroz, Jean-Luc Wolfender, Pierre-Alain Carrupt, Alessandra Nurisso
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 8, Iss 2, p e2689 (2014)
BACKGROUND: The silent-information regulator 2 proteins, otherwise called sirtuins, are currently considered as emerging anti-parasitic targets. Nicotinamide, a pan-sirtuin inhibitor, is known to cause kinetoplast alterations and the arrested growth
Externí odkaz:
https://doaj.org/article/f704bf9983f84b8698f64c03a2e2ad8a
Autor:
Alessandra Nurisso, Claudia Simoes-Pires, Sophie Martel, Delphine Cressend, Amandine Guillot, Pierre-Alain Carrupt
Publikováno v:
CHIMIA, Vol 66, Iss 5 (2012)
Successful drug design requires not only the detailed knowledge of the pharmacokinetic and pharmacodynamic profiles of the drug candidate portfolio but also a thorough documentation of the possible toxic effects on humans and the environment. Thus, e
Externí odkaz:
https://doaj.org/article/d47d22e2530d48b0a8b851b12d6ad4fb
Autor:
Eric Chabrol, Alessandra Nurisso, Antoine Daina, Emilie Vassal-Stermann, Michel Thepaut, Eric Girard, Romain R Vivès, Franck Fieschi
Publikováno v:
PLoS ONE, Vol 7, Iss 11, p e50722 (2012)
Langerin is a C-type lectin specifically expressed in Langerhans cells. As recently shown for HIV, Langerin is thought to capture pathogens and mediate their internalisation into Birbeck Granules for elimination. However, the precise functions of Lan
Externí odkaz:
https://doaj.org/article/38392944678f4cabaa759de9ff7ba8a4
Autor:
Claudia A. Simões-Pires, Yung-Sing Wong, Mohamed Dit Mady Traoré, Vincent Zwick, Sharon Wein, Muriel Cuendet, Marjorie Maynadier, Mark E. Issa, Alessandra Nurisso, Henri Vial, Hélène Jamet
Publikováno v:
ACSOmega
ACS Omega
ACS Omega, Vol. 2, No 4 (2017) pp. 1550-1562
ACS Omega, Vol 2, Iss 4, Pp 1550-1562 (2017)
ACS Omega, ACS Publications, 2017, 2 (4), pp.1550-1562. ⟨10.1021/acsomega.6b00481⟩
ACS Omega
ACS Omega, Vol. 2, No 4 (2017) pp. 1550-1562
ACS Omega, Vol 2, Iss 4, Pp 1550-1562 (2017)
ACS Omega, ACS Publications, 2017, 2 (4), pp.1550-1562. ⟨10.1021/acsomega.6b00481⟩
Little is known about the biological and structural features that govern the isoform selectivity for class I histone deacetylases (HDACs) over HDAC6. In addition to that for known inhibitors, like benzamides, psammaplin A, and cyclodepsipeptide-deriv
Autor:
Vincent Zwick, Giuseppe Marco Randazzo, Claudia A. Simões-Pires, Muriel Cuendet, Philippe Bertrand, Carolina dos Santos Passos, Nadine Martinet, Charlotte Petit, Alessandra Nurisso
Publikováno v:
Bioorganic & Medicinal Chemistry Letters
Bioorganic & Medicinal Chemistry Letters, Vol. 26, No 20 (2016) pp. 4955-4959
Bioorganic & Medicinal Chemistry Letters, Vol. 26, No 20 (2016) pp. 4955-4959
In recent years, the role of HDAC6 in neurodegeneration has been partially elucidated, which led some authors to propose HDAC6 inhibitors as a therapeutic strategy to treat neurodegenerative diseases. In an effort to develop a selective HDAC6 inhibit
The molecular lipophilicity potential (MLP) is a well-established method to calculate and visualize lipophilicity on molecules. We are here introducing a new computational tool named MLP Tools, written in the programming language Python, and conceive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::228d5105ef37a36b9aede20b3562a533
http://doc.rero.ch/record/324915/files/10822_2014_Article_9744.pdf
http://doc.rero.ch/record/324915/files/10822_2014_Article_9744.pdf
Autor:
Jean-Jacques Bono, Virginie Gasciolli, Antonius C.J. Timmers, Judith Fliegmann, Julie Cullimore, Nikita Malkov, Charles Rosenberg, Alessandra Nurisso
Publikováno v:
Biochemical Journal
Biochemical Journal, Portland Press, 2016, 473, pp.1369-1378. ⟨10.1042/BCJ20160073⟩
Biochemical Journal, Portland Press, 2016, 473, pp.1369-1378. ⟨10.1042/BCJ20160073⟩
International audience; LYR3 [LysM (lysin motif) receptor-like kinase 3] of Medicago truncatula is a high-affinity binding protein for symbiotic LCO (lipo-chitooligosaccharide) signals, produced by rhizobia bacteria and arbuscular mycorrhizal fungi.