Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Alessandra, Piccini"'
Autor:
Alessandra Piccini, Enrico Castroflorio, Pierluigi Valente, Fabrizia C. Guarnieri, Davide Aprile, Caterina Michetti, Mattia Bramini, Giorgia Giansante, Bruno Pinto, Annalisa Savardi, Fabrizia Cesca, Angela Bachi, Angela Cattaneo, Jonathan D. Wren, Anna Fassio, Flavia Valtorta, Fabio Benfenati, Silvia Giovedì
Publikováno v:
Cell Reports, Vol 21, Iss 12, Pp 3596-3611 (2017)
Summary: Synaptic transmission is critically dependent on synaptic vesicle (SV) recycling. Although the precise mechanisms of SV retrieval are still debated, it is widely accepted that a fundamental role is played by clathrin-mediated endocytosis, a
Externí odkaz:
https://doaj.org/article/bd9583cca84a42b3ac35a1011942d8d2
Autor:
Laura E. Perlini, Joanna Szczurkowska, Bryan A. Ballif, Alessandra Piccini, Silvio Sacchetti, Silvia Giovedì, Fabio Benfenati, Laura Cancedda
Publikováno v:
Cell Reports, Vol 11, Iss 2, Pp 234-248 (2015)
Synapsin III (SynIII) is a phosphoprotein that is highly expressed at early stages of neuronal development. Whereas in vitro evidence suggests a role for SynIII in neuronal differentiation, in vivo evidence is lacking. Here, we demonstrate that in vi
Externí odkaz:
https://doaj.org/article/090a3452c84f4814a489c7058f1c3004
Autor:
Fabiola Mastropietro, Alessandra Piccini, Giulia Lucignani, Alfonso Rubino, Giancarlo Fiermonte
Publikováno v:
Clinical Management Issues, Vol 8, Iss 4, Pp 103-107 (2014)
Lymphomas infrequently cause peripheral nerve complications. These syndromes mostly occur by direct compression or infiltration of nerves (neurolymphomatosis), but may also be due to a remote effect as paraneoplastic syndromes, neurotoxic complicatio
Externí odkaz:
https://doaj.org/article/36b880abc56e48e0bb2f92d85ecf4736
Autor:
Alessandra Piccini, Anna Fassio, Elena Pasqualetto, Antonella Vitali, Roberta Borghi, Daniela Palmieri, Benedetta Nacmias, Sandro Sorbi, Roberto Sitia, Massimo Tabaton
Publikováno v:
Neurobiology of Disease, Vol 15, Iss 2, Pp 380-386 (2004)
Many patients affected by early onset familial Alzheimer's disease (FAD), carry mutations in the presenilin 1 (PS1) gene. Since it has been suggested that FAD-linked PS1 mutations impair the unfolded protein response (UPR) due to endoplasmic reticulu
Externí odkaz:
https://doaj.org/article/b2ca97ac89ff4dbfa38e0aa04dc487c0
Autor:
Giambattista Bonanno, Alessandra Piccini, Paul J. Lombroso, Silvia Giovedì, Marco Milanese, Fabio Benfenati, Pietro Baldelli, Pierluigi Valente, Federica Bosco, Mirko Messa
Publikováno v:
Molecular Neurobiology. 55:8084-8102
The striatal-enriched protein tyrosine phosphatase (STEP) is a brain-specific phosphatase involved in synaptic transmission. The current hypothesis on STEP function holds that it opposes synaptic strengthening by dephosphorylating and inactivating ke
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b870315e50ccd72a56d98dea287db9e1
https://doi.org/10.1007/s12035-018-0980-5
https://doi.org/10.1007/s12035-018-0980-5
Autor:
Laura Colombo, Roberta Borghi, Anna Garuti, Valeria Pollero, Gabriella Cirmena, Sergio Cammarata, Michele Fornaro, Massimo Messa, Massimo Tabaton, Alessandra Piccini, Mario Salmona, Michela Guglielmotto, George Perry, Elena Tamagno
Publikováno v:
Journal of Neurochemistry. 122:1023-1031
J. Neurochem. (2012) 122, 1023–1031. Abstract The pathogenesis of Alzheimer’s disease (AD) is only partially understood. β-amyloid (Aβ) is physiologically generated by sequential cleavage of its precursor protein by the β- and the γ-secretase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c09331ef40d8db6c611d7548b6ca99c8
https://doi.org/10.1111/j.1471-4159.2012.07834.x
https://doi.org/10.1111/j.1471-4159.2012.07834.x
Autor:
Alessandra Piccini
Publikováno v:
The Open Nuclear Medicine Journal. 2:25-30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::59ab0821ae01077f490a6f5933429bc2
https://doi.org/10.2174/1876388x01002010025
https://doi.org/10.2174/1876388x01002010025
Autor:
Debora Mazzei, Barbara Dessi, Silvia Morbelli, Giampiero Villavecchia, Stig A. Larsson, Andrea Brugnolo, Marco Pagani, Guido Rodriguez, Flavio Nobili, Dario Salmaso, Alessandra Piccini
Publikováno v:
Current Alzheimer Research. 7:287-294
Patients with Mild Cognitive Impairment (MCI) not converted to dementia at one to three years follow-up represent a heterogeneous group across studies, by including 'late converters' but also patients without any neurodegenerative disease. We tested
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83d29ab1e88dcffddebf19133f518bd9
https://doi.org/10.2174/156720510791162368
https://doi.org/10.2174/156720510791162368
Autor:
Alessandra Piccini
Publikováno v:
The Open Nuclear Medicine Journal. 2:25-30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7bd4fa42761c2f60423b4b8bfee6777f
https://doi.org/10.2174/1876388x01002020025
https://doi.org/10.2174/1876388x01002020025
Autor:
Roberta Borghi, Mohamed R. Mughal, Sandro Sorbi, Xiongwei Zhu, Xinglong Wang, Anna Garuti, Rosa Mangerini, Bernardino Ghetti, Fabrizio Tagliavini, Massimo Tabaton, Gabriella Cirmena, Elena Tamagno, Luca Giliberto, Mark P. Mattson, Michela Guglielmotto, Alessandra Piccini
Publikováno v:
Journal of Biological Chemistry. 284:9027-9038
Mutations of the presenilin 1 (PS1) gene are the most common cause of early onset familial Alzheimer disease (FAD). PS1 mutations alter the activity of the gamma-secretase on the beta-amyloid precursor protein (APP), leading to selective overproducti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61f7f94839ae203a3e93def16f5d96c6
https://doi.org/10.1074/jbc.m805685200
https://doi.org/10.1074/jbc.m805685200