Zobrazeno 1 - 10
of 129
pro vyhledávání: '"Alessandra, Colombini"'
Autor:
Alessandra Colombini, Gianluca Doro, Enrico Ragni, Luca Forte, Laura de Girolamo, Fabio Zerbinati
Publikováno v:
BMC Musculoskeletal Disorders, Vol 24, Iss 1, Pp 1-11 (2023)
Abstract Background Knee osteoarthritis (OA) is a progressive and degenerative condition. Several pharmacological and non-pharmacological treatments are able to improve the OA symptoms and the structural characteristics of the affected joints. Among
Externí odkaz:
https://doaj.org/article/bb3a823d3fec471fb879c3a88145c9a3
Autor:
Carlotta Mondadori, Amit Chandrakar, Silvia Lopa, Paul Wieringa, Giuseppe Talò, Silvia Perego, Giovanni Lombardi, Alessandra Colombini, Matteo Moretti, Lorenzo Moroni
Publikováno v:
Bioactive Materials, Vol 21, Iss , Pp 209-222 (2023)
The dual role of macrophages in the healing process depends on macrophage ability to polarize into phenotypes that can propagate inflammation or exert anti-inflammatory and tissue-remodeling functions. Controlling scaffold geometry has been proposed
Externí odkaz:
https://doaj.org/article/8ec1e8c2c322498481e66cd76f4b15e4
Autor:
Silvia Lopa, Francesca Libonati, Katia Mareschi, Giuseppe Talò, Stefania Brambilla, Vincenzo Raffo, Luciana Labanca, Luigi Zagra, Matteo Moretti, Laura de Girolamo, Alessandra Colombini
Publikováno v:
Biomedicines, Vol 12, Iss 4, p 833 (2024)
Macrophage-based co-cultures are used to test the immunomodulatory function of candidate cells for clinical use. This study aimed to characterize a macrophage polarization model using human platelet lysate (hPL) as a GMP-compliant alternative to Feta
Externí odkaz:
https://doaj.org/article/69237daeb93549f6bb2996a2a63739e3
Autor:
Emiliano Marasco, Gianluigi Fabbriciani, Laura Rotunno, Matteo Longhi, Paola De Luca, Laura de Girolamo, Alessandra Colombini
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionRheumatoid arthritis (RA) is an inflammatory autoimmune disease that may cause joint destruction and disability. The pharmacological treatment of RA aims at obtaining disease remission by effectively ceasing joint inflammation and arresti
Externí odkaz:
https://doaj.org/article/5efcc5d54c3a4a40932e8a1b5ef6cef8
Autor:
Tito Bassani, Andrea Cina, Fabio Galbusera, Luca Maria Sconfienza, Domenico Albano, Federica Barcellona, Alessandra Colombini, Andrea Luca, Marco Brayda-Bruno
Publikováno v:
Frontiers in Surgery, Vol 10 (2023)
IntroductionA novel classification scheme for endplate lesions, based on T2-weighted images from magnetic resonance imaging (MRI) scan, has been recently introduced and validated. The scheme categorizes intervertebral spaces as “normal,” “wavy/
Externí odkaz:
https://doaj.org/article/74f8bd313d9f4ef5926510e9df513337
Inflammatory priming with IL-1β promotes the immunomodulatory behavior of adipose derived stem cells
Autor:
Alessandra Colombini, Francesca Libonati, Davide Cangelosi, Silvia Lopa, Paola De Luca, Domenico Antonio Coviello, Matteo Moretti, Laura de Girolamo
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 10 (2022)
Inflammatory processes contribute to osteoarthritis (OA) severity and progression. Mesenchymal stem cells, particularly those derived from adipose tissue (ASCs), are able to sense and control the inflammatory environment. This immunomodulatory potent
Externí odkaz:
https://doaj.org/article/bd2973dd16684f929ac724ca95d9f0a0
Autor:
Alessandra Colombini, Francesca Libonati, Silvia Lopa, Enrico Ragni, Paola De Luca, Luigi Zagra, Federico Sinigaglia, Matteo Moretti, Laura de Girolamo
Publikováno v:
Frontiers in Medicine, Vol 9 (2022)
The purpose of the present study is to predict by bioinformatics the activity of the extracellular vesicle (EV)-embedded micro RNA (miRNAs) secreted by cartilage cells (CCs), adipose tissue-derived- (ASCs), and bone marrow-derived stem cells (BMSCs)
Externí odkaz:
https://doaj.org/article/0edafc9b952e440ba4348cdbd7456fec
Autor:
Enrico Ragni, Andrea Papait, Carlotta Perucca Orfei, Antonietta Rosa Silini, Alessandra Colombini, Marco Viganò, Francesca Libonati, Ornella Parolini, Laura deGirolamo
Publikováno v:
Stem Cells Translational Medicine, Vol 10, Iss 7, Pp 1044-1062 (2021)
Abstract Human amniotic membrane‐derived mesenchymal stromal cells (hAMSCs) are easily obtained in large quantities and free from ethical concerns. Promising therapeutic results for both hAMSCs and their secreted factors (secretome) were described
Externí odkaz:
https://doaj.org/article/14c321ff07604eaea4507b2fc0468005
Autor:
Enrico Ragni, Carlotta Perucca Orfei, Paola De Luca, Carlotta Mondadori, Marco Viganò, Alessandra Colombini, Laura de Girolamo
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-19 (2020)
Abstract Background Mesenchymal stromal cell (MSC)-enriched products showed positive clinical outcomes in regenerative medicine, where tissue restoration and inflammation control are needed. GMP-expanded MSCs displayed an even higher potential due to
Externí odkaz:
https://doaj.org/article/65882c7b49054d5484e583d869afe1da
Autor:
Alessio Lovi, Enrico Gallazzi, Fabio Galbusera, Alessandra Colombini, Fabrizio Pregliasco, Giuseppe Peretti, Marco Brayda-Bruno
Publikováno v:
Brain and Spine, Vol 2, Iss , Pp 100858- (2022)
Introduction: A precise knowledge of the possible Adverse Events (AEs) related to spinal surgical procedures is crucial in clinical practice. Research Question: Purposes of this study are: to determine the prevalence and severity of perioperative AEs
Externí odkaz:
https://doaj.org/article/7c91ce7191134bc2b5fc788da932e344