Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Alesia Miloslavina"'
Autor:
Diana Imhof, Jana Schirmeyer, Alesia Miloslavina, Michael Kijas, René Markgraf, Stefan H. Heinemann, Enrico Leipold
Publikováno v:
Neuropharmacology. 61:105-111
Voltage-gated sodium channels (Na(V) channels) play a pivotal role in neuronal excitability; they are specifically targeted by μ-conotoxins from the venom of marine cone snails. These peptide toxins bind to the outer vestibule of the channel pore th
Autor:
Christina Ebert, Diana Imhof, Daniel Tietze, Matthias Görlach, Christoph Englert, Oliver Ohlenschläger, Alesia Miloslavina
Publikováno v:
Peptides. 31:1292-1300
The venom of marine cone snails contains a variety of conformationally constrained peptides utilized by the animal to capture prey. Besides numerous conotoxins, which are characterized by complex disulfide patterns, other peptides with only a single
Autor:
Enrico Leipold, Michael Kijas, Stefan H. Heinemann, Diana Imhof, Annegret Stark, Alesia Miloslavina
Publikováno v:
Journal of Peptide Science. 15:72-77
We report the first example of conopeptide oxidation performed in a biocompatible ionic liquid, 1-ethyl-3-methylimidazolium acetate ([C(2)mim][OAc]), which enables the efficient formation of both hydrophilic and poorly water-soluble conotoxins compar
Publikováno v:
Tetrahedron Letters. 45:3583-3584
Cyclooctatetraene, C8H8, has been made readily available from 1,5-cyclooctadiene in 65% yield without the need of using hazardous or toxic reagents by the straightforward oxidation of the intermediate [Li(tmeda)]2C8H8 ( 3 , tmeda=N,N,N′,N′-tetram