Výsledky vyhledávání - "Alesia Harper"

Akademický článek

Associations Between Soluble fms‐Like Tyrosine Kinase‐1 and Placental Growth Factor and Disease Severity Among Women With Preterm Eclampsia and Preeclampsia

Autor: Roxanne Hastie, Lina Bergman, Susan P. Walker, Tu'uhevaha Kaitu'u‐Lino, Natalie J. Hannan, Fiona Brownfoot, Sonja Schell, Alesia Harper, Ping Cannon, Catherine A. Cluver, Stephen Tong

Publikováno v: Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 11, Iss 16 (2022)

Background The angiogenic factors soluble fms‐like tyrosine kinase‐1 (sFlt‐1) and placental growth factor (PlGF) are postulated to be pathogenic disease drivers of preeclampsia. If true, then circulating levels should become more deranged with

Externí odkaz: https://doaj.org/article/ce31eed7eed84510833ab10efcf561d1

Zobrazit plný text záznamu

Akademický článek

Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

Publikováno v: Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)

There are no reliable tests for placental insufficiency, which can lead to fetal growth restriction and stillbirth. Here the authors demonstrate that low levels of circulating SPINT1 are associated to low birthweight, and several ultrasound and neona

Externí odkaz: https://doaj.org/article/b241206eb8c94b78bb67bfb73fc52e4f

Zobrazit plný text záznamu

Akademický článek

Hydroxychloroquine reduces soluble Flt-1 secretion from human cytotrophoblast, but does not mitigate markers of endothelial dysfunction in vitro.

Autor: Elif Kadife, Natalie Hannan, Alesia Harper, Natalie Binder, Sally Beard, Fiona C Brownfoot

Publikováno v: PLoS ONE, Vol 17, Iss 11, p e0271560 (2022)

Preeclampsia is a multi-system disease that can have severe, even fatal implications for the mother and fetus. Abnormal placentation can lead to ischaemic tissue injury and placental inflammation. In turn, the placenta releases anti-angiogenic factor

Externí odkaz: https://doaj.org/article/ce41406c48294099971b0d7847ef6f09

Zobrazit plný text záznamu

Plný text ve formátu HTML

Akademický článek

Screening circulating proteins to identify biomarkers of fetal macrosomia

Autor: Tess Cruickshank, Tu’uhevaha J. Kaitu’u-Lino, Ping Cannon, Alesia Harper, Tuong-Vi Nguyen, Kirsten M. Dane, Anna L. Middleton, Valerie P. Kyritsis, Roxanne Hastie, Stephen Tong, Susan P. Walker, Teresa M. MacDonald

Publikováno v: BMC Research Notes, Vol 12, Iss 1, Pp 1-6 (2019)

Abstract Objective Fetal macrosomia is a major risk factor for shoulder dystocia, which can lead to birth asphyxia, maternal and neonatal traumatic injuries, and perinatal death. If macrosomia is diagnosed in the antenatal period, labour can be induc

Externí odkaz: https://doaj.org/article/17dbc170aead4769b61c8216247f585d

Zobrazit plný text záznamu

Plný text ve formátu HTML

Sulfasalazine for the treatment of preeclampsia in a nitric oxide synthase antagonist mouse model

Autor: Natalie K. Binder, Natasha de Alwis, Sally Beard, Elif Kadife, Alesia Harper, Tu'uhevaha J. Kaitu'u-Lino, Fiona C. Brownfoot, Natalie J. Hannan

Publikováno v: Placenta. 132:20-26

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e4605c5ab684c7e7aeb939f3d712bfd6
https://doi.org/10.1016/j.placenta.2023.01.001

Zobrazit plný text záznamu

Novel genes associated with a placental phenotype in knockout mice also respond to cellular stressors in primary human trophoblasts

Autor: Elif Kadife, Alesia Harper, Keegan Chien, Tu'uhevaha Kaitu-u Lino, Fiona C. Brownfoot

Publikováno v: Placenta.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e179f83dd89aa2e9fa8ed4f6f9a812e3
https://doi.org/10.1016/j.placenta.2023.05.012

Zobrazit plný text záznamu

SLC38A4 Amino Acid Transporter Expression Is Significantly Lower in Early Preterm Intrauterine Growth Restriction Complicated Placentas

Autor: Elif Kadife, Alesia Harper, Natasha De Alwis, Keegan Chien, Natalie Hannan, Fiona C. Brownfoot

Publikováno v: International Journal of Molecular Sciences; Volume 24; Issue 1; Pages: 403

Intrauterine growth restriction (IUGR), predominantly caused by placental insufficiency, affects partitioning of nutrients to the fetus. The system A sodium-coupled transporters (SNAT or SLC38), of types A1, A2, and A4, control non-essential amino ac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbe8d05fc398c3b587078a55b4d030a0

Zobrazit plný text záznamu

Plný text ve formátu HTML

Chronic Atrazine Exposure Beginning Prenatally Impacts Liver Function and Sperm Concentration With Multi-Generational Consequences in Mice

Autor: Bethany J Finger, Alesia Harper, Mark P. Green

Publikováno v: Frontiers in Endocrinology, Vol 11 (2020)
Frontiers in Endocrinology

Atrazine is a commonly used herbicide frequently detected in waterways and drinking water around the world. Worryingly, atrazine is an endocrine and metabolic disruptor but there is a lack of research regarding the effects of long-term exposure begin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7455478d69b8accbda0095d973ed9740
https://www.frontiersin.org/articles/10.3389/fendo.2020.580124/full

Zobrazit plný text záznamu

Nicotinamide and its effects on endothelial dysfunction and secretion of antiangiogenic factors by primary human placental cells and tissues

Autor: Natalie K Binder, Fiona C Brownfoot, Laura Tuohey, Emerson Keenan, Sally Beard, Natalie J. Hannan, Stephen Tong, Alesia Harper, Roxanne Hastie

Publikováno v: Placenta. 109

Preeclampsia is a serious pregnancy complication associated with elevated antiangiogenic markers and endothelial dysfunction. Recently nicotinamide (vitamin B3) was shown to reduce high blood pressure and proteinuria in mice models of the disease. Us

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06cd1f8e7ca0e74903b73442b78c5fc0
https://pubmed.ncbi.nlm.nih.gov/33957335

Zobrazit plný text záznamu

Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction

Publikováno v: Kaitu’u-Lino, T J, MacDonald, T M, Cannon, P, Nguyen, T-V, Hiscock, R J, Haan, N, Myers, J E, Hastie, R, Dane, K M, Middleton, A L, Bittar, I, Sferruzzi-Perri, A N, Pritchard, N, Harper, A, Hannan, N J, Kyritsis, V, Crinis, N, Hui, L, Walker, S P & Tong, S 2020, ' Circulating SPINT1 is a biomarker of pregnancies with poor placental function and fetal growth restriction ', Nature Communications, vol. 11, 2411 . https://doi.org/10.1038/s41467-020-16346-x
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Nature Communications

Funder: RANZCOG Research Foundation (RANZCOG); doi: https://doi.org/10.13039/501100001104
Funder: The Stillbirth Foundation
Funder: Tommy's; doi: https://doi.org/10.13039/501100009324
Funder: National Institute Health Research Manchest

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f46b9a228976d23ee5b53694a4ff1a32
https://doi.org/10.1038/s41467-020-16346-x

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání