Exploring the molecular mechanisms of MSC-derived exosomes in Alzheimer's disease: Autophagy, insulin and the PI3K/Akt/mTOR signaling pathway.

Autor: Ebrahim N; Department of Medical Histology and Cell Biology Faculty of Medicine, Benha University, Benha, Egypt; Stem Cell Unit, Faculty of Medicine, Benha University, Egypt; Benha National University, Faculty of Medicine. student at Keele University, UK; Department of Anatomy, Mansoura Faculty of Medicine, Mansoura University, Egypt. Electronic address: nesrien.salem@med.bnu.edu.eg., Al Saihati HA; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hafr Albatin, Saudi Arabia; Department of Anatomy, Mansoura Faculty of Medicine, Mansoura University, Egypt. Electronic address: zahali@uhb.edu.sa., Alali Z; Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, University of Hafr Al Batin, P.O Box 1803, Hafr Al Batin 31991, Saudi Arabia., Aleniz FQ; Department of Immunology, Collage of Applied Science, Alkharj., Mahmoud SYM; Biology Department, College of Sciences, University of Hafr Al Batin, P. O. Box 1803, Hafar Al Batin 31991, Saudi Arabia. Agricultural Microbiology Department, Faculty of Agriculture, Sohag University, Sohag, Egypt., Badr OA; Department of Genetics and Genetic Engineering, Faculty of Agriculture, Benha University, Benha, Egypt., Dessouky AA; Department of Medical Histology and Cell Biology, Faculty of Medicine, Zagazig University, Egypt., Mostafa O; Department of Medical Histology and Cell Biology Faculty of Medicine, Benha University, Benha, Egypt., Hussien NI; Department of Physiology, Faculty of Medicine, Benha University, Egypt., Farid AS; Department of Clinical Pathology, Faculty of Veterinary Medicine, Benha University, Moshtohor, Toukh, Qalyubia 13736, Egypt., El-Sherbiny M; Department of Basic Medical Sciences, College of Medicine, AlMaarefa University, Riyadh, Saudi Arabia., Salim RF; Department of Medical Biochemistry and molecular biology, Faculty of Medicine, Benha University, Egypt., Forsyth NR; School of Pharmacy and Bioengineering, Keele University. Vice Principals' Office, University of Aberdeen, Kings College, Aberdeen, AB24 3FX, UK., Ali FEM; Department of Pharmacology and Toxicology, Faculty of Pharmacy, Al-Azhar University, Assiut Branch, Assiut, Egypt., Alsabeelah NF; Assistant Professor of Pharmacology Pharmacy Practice Department, Pharmacy College University of Hafr Al Batin, P.O. Box 1803, Hafr Al Batin 31991, Saudi Arabia.

Publikováno v: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Jul; Vol. 176, pp. 116836. Date of Electronic Publication: 2024 Jun 07.